AbstractCardiacPde.cpp

/*

Copyright (C) University of Oxford, 2005-2009

University of Oxford means the Chancellor, Masters and Scholars of the
University of Oxford, having an administrative office at Wellington
Square, Oxford OX1 2JD, UK.

This file is part of Chaste.

Chaste is free software: you can redistribute it and/or modify it
under the terms of the GNU Lesser General Public License as published
by the Free Software Foundation, either version 2.1 of the License, or
(at your option) any later version.

Chaste is distributed in the hope that it will be useful, but WITHOUT
ANY WARRANTY; without even the implied warranty of MERCHANTABILITY or
FITNESS FOR A PARTICULAR PURPOSE.  See the GNU Lesser General Public
License for more details. The offer of Chaste under the terms of the
License is subject to the License being interpreted in accordance with
English Law and subject to any action against the University of Oxford
being under the jurisdiction of the English Courts.

You should have received a copy of the GNU Lesser General Public License
along with Chaste. If not, see <http://www.gnu.org/licenses/>.

*/

#include "AbstractCardiacPde.hpp"

#include "DistributedVector.hpp"
#include "AxisymmetricConductivityTensors.hpp"
#include "OrthotropicConductivityTensors.hpp"
#include "ChastePoint.hpp"
#include "ChasteCuboid.hpp"
#include "HeartEventHandler.hpp"
#include "PetscTools.hpp"
#include "FakeBathCell.hpp"


template <unsigned ELEM_DIM,unsigned SPACE_DIM>
AbstractCardiacPde<ELEM_DIM,SPACE_DIM>::AbstractCardiacPde(
            AbstractCardiacCellFactory<ELEM_DIM,SPACE_DIM>* pCellFactory,
            const unsigned stride)
    : mStride(stride),
      mDoCacheReplication(true),
      mDoOneCacheReplication(true),
      mpDistributedVectorFactory(pCellFactory->GetMesh()->GetDistributedVectorFactory()),
      mpFactoryWasUnarchived(false)
{
    //This constructor is called from the Initialise() method of the CardiacProblem class
    assert(pCellFactory!=NULL);
    assert(pCellFactory->GetMesh()!=NULL);

    unsigned num_local_nodes = mpDistributedVectorFactory->GetLocalOwnership();
    unsigned ownership_range_low = mpDistributedVectorFactory->GetLow(); 
    mCellsDistributed.resize(num_local_nodes);
    
    for (unsigned local_index = 0; local_index < num_local_nodes; local_index++)
    {
        unsigned global_index = ownership_range_low + local_index;
        mCellsDistributed[local_index] = pCellFactory->CreateCardiacCellForNode(global_index);
    }
        
    
    pCellFactory->FinaliseCellCreation(&mCellsDistributed,
                                       pCellFactory->GetMesh()->GetDistributedVectorFactory()->GetLow(),
                                       pCellFactory->GetMesh()->GetDistributedVectorFactory()->GetHigh());


    mIionicCacheReplicated.resize( pCellFactory->GetNumberOfCells() );
    mIntracellularStimulusCacheReplicated.resize( pCellFactory->GetNumberOfCells() );

    mpConfig = HeartConfig::Instance();

    if (mpConfig->IsMeshProvided() && mpConfig->GetLoadMesh())
    {
        switch (mpConfig->GetConductivityMedia())
        {
            case media_type::Orthotropic:
                mpIntracellularConductivityTensors =  new OrthotropicConductivityTensors<SPACE_DIM>;
                mpIntracellularConductivityTensors->SetFibreOrientationFile(mpConfig->GetMeshName() + ".ortho");
                break;

            case media_type::Axisymmetric:
                mpIntracellularConductivityTensors =  new AxisymmetricConductivityTensors<SPACE_DIM>;
                mpIntracellularConductivityTensors->SetFibreOrientationFile(mpConfig->GetMeshName() + ".axi");
                break;

            case media_type::NoFibreOrientation:
                mpIntracellularConductivityTensors =  new OrthotropicConductivityTensors<SPACE_DIM>;
                break;

            default :
                NEVER_REACHED;
        }
    }
    else // Slab defined in config file or SetMesh() called; no fibre orientation assumed
    {
        mpIntracellularConductivityTensors =  new OrthotropicConductivityTensors<SPACE_DIM>;
    }

    c_vector<double, SPACE_DIM> intra_conductivities;
    mpConfig->GetIntracellularConductivities(intra_conductivities);

    // this definition must be here (and not inside the if statement) because SetNonConstantConductivities() will keep
    // a pointer to it and we don't want it to go out of scope before Init() is called
    unsigned num_elements = pCellFactory->GetMesh()->GetNumElements();
    std::vector<c_vector<double, SPACE_DIM> > hetero_intra_conductivities(num_elements);

    if (mpConfig->GetConductivityHeterogeneitiesProvided())
    {
        std::vector<ChasteCuboid> conductivities_heterogeneity_areas;
        std::vector< c_vector<double,3> > intra_h_conductivities;
        std::vector< c_vector<double,3> > extra_h_conductivities;
        HeartConfig::Instance()->GetConductivityHeterogeneities(conductivities_heterogeneity_areas,
                                                                intra_h_conductivities,
                                                                extra_h_conductivities);

        for (unsigned element_index=0; element_index<num_elements; element_index++)
        {
            for (unsigned region_index=0; region_index< conductivities_heterogeneity_areas.size(); region_index++)
            {
                // if element centroid is contained in the region
                ChastePoint<SPACE_DIM> element_centroid(pCellFactory->GetMesh()->GetElement(element_index)->CalculateCentroid());
                if ( conductivities_heterogeneity_areas[region_index].DoesContain(element_centroid) )
                {
                    hetero_intra_conductivities[element_index] = intra_h_conductivities[region_index];
                }
                else
                {
                    hetero_intra_conductivities[element_index] = intra_conductivities;
                }
            }
        }

        mpIntracellularConductivityTensors->SetNonConstantConductivities(&hetero_intra_conductivities);
    }
    else
    {
        mpIntracellularConductivityTensors->SetConstantConductivities(intra_conductivities);
    }

    mpIntracellularConductivityTensors->Init();
}

template <unsigned ELEM_DIM,unsigned SPACE_DIM>
AbstractCardiacPde<ELEM_DIM,SPACE_DIM>::AbstractCardiacPde(std::vector<AbstractCardiacCell*> & rCellsDistributed,
                                                      const unsigned stride)
    : mCellsDistributed(rCellsDistributed),
      mStride(stride),      
      mDoCacheReplication(true),
      mDoOneCacheReplication(true),
      mpDistributedVectorFactory(NULL),
      mpFactoryWasUnarchived(true)
{
    mpIntracellularConductivityTensors = NULL;    
}

template <unsigned ELEM_DIM,unsigned SPACE_DIM>
AbstractCardiacPde<ELEM_DIM,SPACE_DIM>::~AbstractCardiacPde()
{
    for (std::vector<AbstractCardiacCell*>::iterator cell_iterator = mCellsDistributed.begin();
         cell_iterator != mCellsDistributed.end();
         ++cell_iterator)
    {
        // Only delete real cells
        FakeBathCell* p_fake = dynamic_cast<FakeBathCell*>(*cell_iterator);
        if (p_fake == NULL)
        {
            delete (*cell_iterator);
        }
    }

    if (mpIntracellularConductivityTensors)
    {
        delete mpIntracellularConductivityTensors;
    }
    
    // If the distributed vector factory was unarchived we need to free it explicitly. 
    if (mpFactoryWasUnarchived)
    {
        delete mpDistributedVectorFactory;
    }    
}

template <unsigned ELEM_DIM,unsigned SPACE_DIM>
void AbstractCardiacPde<ELEM_DIM,SPACE_DIM>::SetCacheReplication(bool doCacheReplication)
{
    mDoCacheReplication = doCacheReplication;
}

template <unsigned ELEM_DIM,unsigned SPACE_DIM>
const c_matrix<double, SPACE_DIM, SPACE_DIM>& AbstractCardiacPde<ELEM_DIM,SPACE_DIM>::rGetIntracellularConductivityTensor(unsigned elementIndex)
{
    assert( mpIntracellularConductivityTensors);
    return (*mpIntracellularConductivityTensors)[elementIndex];
}

template <unsigned ELEM_DIM,unsigned SPACE_DIM>
AbstractCardiacCell* AbstractCardiacPde<ELEM_DIM,SPACE_DIM>::GetCardiacCell( unsigned globalIndex )
{
    assert(mpDistributedVectorFactory->GetLow() <= globalIndex &&
           globalIndex < mpDistributedVectorFactory->GetHigh());
    return mCellsDistributed[globalIndex - mpDistributedVectorFactory->GetLow()];
}


template <unsigned ELEM_DIM,unsigned SPACE_DIM>
void AbstractCardiacPde<ELEM_DIM,SPACE_DIM>::SolveCellSystems(Vec existingSolution, double time, double nextTime)
{
    HeartEventHandler::BeginEvent(HeartEventHandler::SOLVE_ODES);

    DistributedVector dist_solution = mpDistributedVectorFactory->CreateDistributedVector(existingSolution);
    DistributedVector::Stripe voltage(dist_solution, 0);
    for (DistributedVector::Iterator index = dist_solution.Begin();
         index != dist_solution.End();
         ++index)
    {
        // overwrite the voltage with the input value
        mCellsDistributed[index.Local]->SetVoltage( voltage[index] );
        try
        {
            // solve
            // Note: Voltage should not be updated. GetIIonic will be called later
            // and needs the old voltage. The voltage will be updated from the pde.
            mCellsDistributed[index.Local]->ComputeExceptVoltage(time, nextTime);
        }
        catch (Exception &e)
        {
            PetscTools::ReplicateException(true);
            throw e;
        }

        // update the Iionic and stimulus caches
        UpdateCaches(index.Global, index.Local, nextTime);
    }
    HeartEventHandler::EndEvent(HeartEventHandler::SOLVE_ODES);

    PetscTools::ReplicateException(false);

    HeartEventHandler::BeginEvent(HeartEventHandler::COMMUNICATION);
    if ((mDoCacheReplication)||mDoOneCacheReplication)
    {
        ReplicateCaches();
        mDoOneCacheReplication=false;
    }
    HeartEventHandler::EndEvent(HeartEventHandler::COMMUNICATION);
}

template <unsigned ELEM_DIM,unsigned SPACE_DIM>
ReplicatableVector& AbstractCardiacPde<ELEM_DIM,SPACE_DIM>::rGetIionicCacheReplicated()
{
    return mIionicCacheReplicated;
}

template <unsigned ELEM_DIM,unsigned SPACE_DIM>
ReplicatableVector& AbstractCardiacPde<ELEM_DIM,SPACE_DIM>::rGetIntracellularStimulusCacheReplicated()
{
    return mIntracellularStimulusCacheReplicated;
}

template <unsigned ELEM_DIM,unsigned SPACE_DIM>
void AbstractCardiacPde<ELEM_DIM,SPACE_DIM>::UpdateCaches(unsigned globalIndex, unsigned localIndex, double nextTime)
{
    mIionicCacheReplicated[globalIndex] = mCellsDistributed[localIndex]->GetIIonic();
    mIntracellularStimulusCacheReplicated[globalIndex] = mCellsDistributed[localIndex]->GetIntracellularStimulus(nextTime);
}

template <unsigned ELEM_DIM,unsigned SPACE_DIM>
void AbstractCardiacPde<ELEM_DIM,SPACE_DIM>::ReplicateCaches()
{
    mIionicCacheReplicated.Replicate(mpDistributedVectorFactory->GetLow(), mpDistributedVectorFactory->GetHigh());
    mIntracellularStimulusCacheReplicated.Replicate(mpDistributedVectorFactory->GetLow(), mpDistributedVectorFactory->GetHigh());
}

template <unsigned ELEM_DIM,unsigned SPACE_DIM>
const std::vector<AbstractCardiacCell*>& AbstractCardiacPde<ELEM_DIM,SPACE_DIM>::GetCellsDistributed() const
{
    return mCellsDistributed;    
}

// Explicit instantiation

template class AbstractCardiacPde<1,1>;
template class AbstractCardiacPde<1,2>;
template class AbstractCardiacPde<1,3>;
template class AbstractCardiacPde<2,2>;
template class AbstractCardiacPde<3,3>;

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