00001 /* 00002 00003 Copyright (C) University of Oxford, 2005-2009 00004 00005 University of Oxford means the Chancellor, Masters and Scholars of the 00006 University of Oxford, having an administrative office at Wellington 00007 Square, Oxford OX1 2JD, UK. 00008 00009 This file is part of Chaste. 00010 00011 Chaste is free software: you can redistribute it and/or modify it 00012 under the terms of the GNU Lesser General Public License as published 00013 by the Free Software Foundation, either version 2.1 of the License, or 00014 (at your option) any later version. 00015 00016 Chaste is distributed in the hope that it will be useful, but WITHOUT 00017 ANY WARRANTY; without even the implied warranty of MERCHANTABILITY or 00018 FITNESS FOR A PARTICULAR PURPOSE. See the GNU Lesser General Public 00019 License for more details. The offer of Chaste under the terms of the 00020 License is subject to the License being interpreted in accordance with 00021 English Law and subject to any action against the University of Oxford 00022 being under the jurisdiction of the English Courts. 00023 00024 You should have received a copy of the GNU Lesser General Public License 00025 along with Chaste. If not, see <http://www.gnu.org/licenses/>. 00026 00027 */ 00028 #ifndef ABSTRACTWNTODEBASEDCELLCYCLEMODEL_HPP_ 00029 #define ABSTRACTWNTODEBASEDCELLCYCLEMODEL_HPP_ 00030 00031 #include <boost/serialization/access.hpp> 00032 #include <boost/serialization/is_abstract.hpp> 00033 #include <boost/serialization/base_object.hpp> 00034 00035 #include "AbstractOdeBasedCellCycleModel.hpp" 00036 #include "RungeKutta4IvpOdeSolver.hpp" 00037 #include "CvodeAdaptor.hpp" 00038 #include "WntConcentration.hpp" 00039 00040 // Needs to be included last 00041 #include <boost/serialization/export.hpp> 00042 00055 class AbstractWntOdeBasedCellCycleModel : public AbstractOdeBasedCellCycleModel 00056 { 00057 private: 00058 00060 friend class boost::serialization::access; 00067 template<class Archive> 00068 void serialize(Archive & archive, const unsigned int version) 00069 { 00070 archive & boost::serialization::base_object<AbstractOdeBasedCellCycleModel>(*this); 00071 archive & mDimension; 00072 } 00073 00074 protected: 00075 00076 #ifdef CHASTE_CVODE 00077 00078 static CvodeAdaptor msSolver; 00079 #else 00080 00081 static RungeKutta4IvpOdeSolver msSolver; 00082 #endif //CHASTE_CVODE 00083 00087 unsigned mDimension; 00088 00092 virtual double GetOdeStopTime(); 00093 00097 double GetWntLevel(); 00098 00099 public: 00100 00106 AbstractWntOdeBasedCellCycleModel(unsigned dimension); 00107 00118 AbstractWntOdeBasedCellCycleModel(const AbstractWntOdeBasedCellCycleModel& rOtherModel); 00119 00127 void ResetForDivision(); 00128 00135 void UpdateCellType(); 00136 00141 virtual void ChangeCellTypeDueToCurrentBetaCateninLevel()=0; 00142 00148 unsigned GetDimension(); 00149 00150 }; 00151 00152 BOOST_IS_ABSTRACT(AbstractWntOdeBasedCellCycleModel) 00153 00154 #endif /*ABSTRACTWNTODEBASEDCELLCYCLEMODEL_HPP_*/