MeshBasedTissue.hpp

00001 /*
00002 
00003 Copyright (C) University of Oxford, 2005-2009
00004 
00005 University of Oxford means the Chancellor, Masters and Scholars of the
00006 University of Oxford, having an administrative office at Wellington
00007 Square, Oxford OX1 2JD, UK.
00008 
00009 This file is part of Chaste.
00010 
00011 Chaste is free software: you can redistribute it and/or modify it
00012 under the terms of the GNU Lesser General Public License as published
00013 by the Free Software Foundation, either version 2.1 of the License, or
00014 (at your option) any later version.
00015 
00016 Chaste is distributed in the hope that it will be useful, but WITHOUT
00017 ANY WARRANTY; without even the implied warranty of MERCHANTABILITY or
00018 FITNESS FOR A PARTICULAR PURPOSE.  See the GNU Lesser General Public
00019 License for more details. The offer of Chaste under the terms of the
00020 License is subject to the License being interpreted in accordance with
00021 English Law and subject to any action against the University of Oxford
00022 being under the jurisdiction of the English Courts.
00023 
00024 You should have received a copy of the GNU Lesser General Public License
00025 along with Chaste. If not, see <http://www.gnu.org/licenses/>.
00026 
00027 */
00028 #ifndef MESHBASEDTISSUE_HPP_
00029 #define MESHBASEDTISSUE_HPP_
00030 
00031 #include "AbstractCellCentreBasedTissue.hpp"
00032 #include "MutableMesh.hpp"
00033 #include "VoronoiTessellation.hpp"
00034 #include "Exception.hpp"
00035 #include "ArchiveLocationInfo.hpp"
00036 #include "TrianglesMeshReader.hpp"
00037 
00038 #include <boost/serialization/access.hpp>
00039 #include <boost/serialization/base_object.hpp>
00040 #include <boost/serialization/set.hpp>
00041 #include <boost/serialization/vector.hpp>
00042 
00043 
00051 template<unsigned DIM>
00052 class MeshBasedTissue : public AbstractCellCentreBasedTissue<DIM>
00053 {
00054     friend class TestMeshBasedTissue;
00055 private:
00057     friend class boost::serialization::access;
00069     template<class Archive>
00070     void serialize(Archive & archive, const unsigned int version)
00071     {
00072         archive & boost::serialization::base_object<AbstractCellCentreBasedTissue<DIM> >(*this);
00073 
00074         // The Voronoi stuff can't be archived yet
00075         //archive & mpVoronoiTessellation
00076         delete mpVoronoiTessellation;
00077         mpVoronoiTessellation = NULL;
00078 
00079         archive & mMarkedSprings;
00080         archive & mUseAreaBasedDampingConstant;
00081 
00082         // In its present form, a call to MeshBasedTissue::Validate() here
00083         // would result in a seg fault in the situation where we are actually loading
00084         // a MeshBasedTissueWithGhostNodes. Commenting out this call breaks no tests.
00085 
00086         //this->Update();
00087         this->Validate();
00088     }
00089 
00090 protected:
00091 #define COVERAGE_IGNORE //Avoid prototypes being treated as code by gcov
00092 
00093     MutableMesh<DIM, DIM>& mrMesh;
00094 
00099     VoronoiTessellation<DIM> *mpVoronoiTessellation;
00100 
00105     bool mDeleteMesh;
00106 
00112     std::set<std::set<TissueCell*> > mMarkedSprings;
00113 
00115     out_stream mpElementFile;
00116 
00118     out_stream mpVoronoiFile;
00119 
00121     out_stream mpTissueAreasFile;
00122 
00124     out_stream mpCellAreasFile;
00125 
00127     std::set<TissueCell*> CreateCellPair(TissueCell&, TissueCell&);
00128 
00130     bool mUseAreaBasedDampingConstant;
00131 #undef COVERAGE_IGNORE //Avoid prototypes being treated as code by gcov
00132 
00138     virtual void UpdateGhostNodesAfterReMesh(NodeMap& rMap);
00139 
00144     virtual void Validate();
00145 
00146 public:
00147 #define COVERAGE_IGNORE //Avoid prototypes being treated as code by gcov
00148 
00160     MeshBasedTissue(MutableMesh<DIM, DIM>& rMesh,
00161                     const std::vector<TissueCell>& rCells,
00162                     const std::vector<unsigned> locationIndices=std::vector<unsigned>(),
00163                     bool deleteMesh=false,
00164                     bool validate=true);
00165 
00171     MeshBasedTissue(MutableMesh<DIM, DIM>& rMesh);
00172 
00176     ~MeshBasedTissue();
00177 
00181     MutableMesh<DIM, DIM>& rGetMesh();
00182 
00186     const MutableMesh<DIM, DIM>& rGetMesh() const;
00187 
00189     bool GetWriteVoronoiData();
00190 
00192     bool GetWriteTissueAreas();
00193 
00195     bool UseAreaBasedDampingConstant();
00196 
00202     void SetOutputVoronoiData(bool writeVoronoiData);
00203 
00212     unsigned AddNode(Node<DIM>* pNewNode);
00213 
00222     void SetNode(unsigned nodeIndex, ChastePoint<DIM>& rNewLocation);
00223 
00232     virtual bool IsGhostNode(unsigned index);
00233 
00241     double GetDampingConstant(unsigned nodeIndex);
00242 
00249     void SetOutputTissueAreas(bool writeTissueAreas);
00250 
00256     void SetAreaBasedDampingConstant(bool useAreaBasedDampingConstant);
00257 
00270     virtual unsigned RemoveDeadCells();
00271 
00283     virtual TissueCell* AddCell(TissueCell& rNewCell, c_vector<double,DIM> newLocation, TissueCell* pParentCell=NULL);
00284 
00291     void CreateOutputFiles(const std::string& rDirectory, bool cleanOutputDirectory);
00292 
00296     void CloseOutputFiles();
00297 
00301     void WriteResultsToFiles();
00302 
00310     virtual void Update(bool hasHadBirthsOrDeaths=true);
00311 
00319     Node<DIM>* GetNode(unsigned index);
00320 
00326     unsigned GetNumNodes();
00327 
00332     void SetBottomCellAncestors();
00333 
00337     void WriteVoronoiResultsToFile();
00338 
00346     void WriteTissueAreaResultsToFile();
00347 
00357     void WriteCellAreaResultsToFile();
00358 
00362     void CreateVoronoiTessellation();
00363 
00367     VoronoiTessellation<DIM>& rGetVoronoiTessellation();
00368 
00374     class SpringIterator
00375     {
00376     public:
00377 
00381         Node<DIM>* GetNodeA();
00382 
00386         Node<DIM>* GetNodeB();
00387 
00391         TissueCell& rGetCellA();
00392 
00396         TissueCell& rGetCellB();
00397 
00403         bool operator!=(const MeshBasedTissue<DIM>::SpringIterator& rOther);
00404 
00408         SpringIterator& operator++();
00409 
00416         SpringIterator(MeshBasedTissue<DIM>& rTissue, typename MutableMesh<DIM,DIM>::EdgeIterator edgeIter);
00417 
00418     private:
00419 
00421         std::set<std::set<unsigned> > mSpringsVisited;
00422 
00424         MeshBasedTissue<DIM>& mrTissue;
00425 
00427         typename MutableMesh<DIM, DIM>::EdgeIterator mEdgeIter;
00428     };
00429 
00433     SpringIterator SpringsBegin();
00434 
00438     SpringIterator SpringsEnd();
00439 
00443     void CheckTissueCellPointers();
00444 
00448     bool IsMarkedSpring(TissueCell&, TissueCell&);
00449 
00453     void MarkSpring(TissueCell&, TissueCell&);
00454 
00458     void UnmarkSpring(TissueCell&, TissueCell&);
00459 
00460 };
00461 #undef COVERAGE_IGNORE //Avoid prototypes being treated as code by gcov
00462 
00463 
00464 #include "TemplatedExport.hpp"
00465 EXPORT_TEMPLATE_CLASS_SAME_DIMS(MeshBasedTissue)
00466 
00467 namespace boost
00468 {
00469 namespace serialization
00470 {
00474 template<class Archive, unsigned DIM>
00475 inline void save_construct_data(
00476     Archive & ar, const MeshBasedTissue<DIM> * t, const BOOST_PFTO unsigned int file_version)
00477 {
00478     // Save data required to construct instance
00479     const MutableMesh<DIM,DIM> *p_mesh = &(t->rGetMesh());
00480     ar & p_mesh;
00481 }
00482 
00487 template<class Archive, unsigned DIM>
00488 inline void load_construct_data(
00489     Archive & ar, MeshBasedTissue<DIM> * t, const unsigned int file_version)
00490 {
00491     // Retrieve data from archive required to construct new instance
00492     MutableMesh<DIM,DIM> *p_mesh;
00493     ar >> p_mesh;
00494 
00495     // Invoke inplace constructor to initialise instance
00496     ::new(t)MeshBasedTissue<DIM>(*p_mesh);
00497 }
00498 }
00499 } // namespace ...
00500 
00501 #endif /*MESHBASEDTISSUE_HPP_*/

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