00001 /* 00002 00003 Copyright (C) University of Oxford, 2005-2009 00004 00005 University of Oxford means the Chancellor, Masters and Scholars of the 00006 University of Oxford, having an administrative office at Wellington 00007 Square, Oxford OX1 2JD, UK. 00008 00009 This file is part of Chaste. 00010 00011 Chaste is free software: you can redistribute it and/or modify it 00012 under the terms of the GNU Lesser General Public License as published 00013 by the Free Software Foundation, either version 2.1 of the License, or 00014 (at your option) any later version. 00015 00016 Chaste is distributed in the hope that it will be useful, but WITHOUT 00017 ANY WARRANTY; without even the implied warranty of MERCHANTABILITY or 00018 FITNESS FOR A PARTICULAR PURPOSE. See the GNU Lesser General Public 00019 License for more details. The offer of Chaste under the terms of the 00020 License is subject to the License being interpreted in accordance with 00021 English Law and subject to any action against the University of Oxford 00022 being under the jurisdiction of the English Courts. 00023 00024 You should have received a copy of the GNU Lesser General Public License 00025 along with Chaste. If not, see <http://www.gnu.org/licenses/>. 00026 00027 */ 00028 #ifndef WNTCONCENTRATION_HPP_ 00029 #define WNTCONCENTRATION_HPP_ 00030 00031 #include <boost/serialization/access.hpp> 00032 #include <boost/serialization/base_object.hpp> 00033 00034 #include <iostream> 00035 00036 #include "MeshBasedTissue.hpp" 00037 00038 // Needs to be included last 00039 #include <boost/serialization/export.hpp> 00040 00047 typedef enum WntConcentrationType_ 00048 { 00049 NONE, 00050 LINEAR, 00051 RADIAL 00052 } WntConcentrationType; 00053 00054 00058 template<unsigned DIM> 00059 class WntConcentration 00060 { 00061 private: 00062 00064 static WntConcentration *mpInstance; 00065 00067 TissueConfig *mpTissueConfig; 00068 00075 WntConcentrationType mWntType; 00076 00080 AbstractTissue<DIM> *mpTissue; 00081 00085 bool mTypeSet; 00086 00090 double mConstantWntValueForTesting; 00091 00096 bool mUseConstantWntValueForTesting; 00097 00099 friend class boost::serialization::access; 00106 template<class Archive> 00107 void serialize(Archive & archive, const unsigned int version) 00108 { 00109 mpTissueConfig = TissueConfig::Instance(); 00110 archive & *mpTissueConfig; 00111 archive & mpTissueConfig; 00112 archive & mWntType; 00113 archive & mpTissue; 00114 archive & mTypeSet; 00115 archive & mConstantWntValueForTesting; 00116 archive & mUseConstantWntValueForTesting; 00117 } 00118 00119 protected: 00120 00124 WntConcentration(); 00125 00126 public: 00127 00134 static WntConcentration* Instance(); 00135 00139 virtual ~WntConcentration(); 00140 00145 static void Destroy(); 00146 00154 double GetWntLevel(double height); 00155 00164 double GetWntLevel(TissueCell* pCell); 00165 00172 c_vector<double, DIM> GetWntGradient(c_vector<double, DIM> location); 00173 00181 c_vector<double, DIM> GetWntGradient(TissueCell* pCell); 00182 00188 void SetTissue(AbstractTissue<DIM>& rTissue); 00189 00193 WntConcentrationType GetType(); 00194 00200 void SetType(WntConcentrationType type); 00201 00208 void SetConstantWntValueForTesting(double value); 00209 00220 bool IsWntSetUp(); 00221 00222 }; 00223 00224 #endif /*WNTCONCENTRATION_HPP_*/