00001 /* 00002 00003 Copyright (C) University of Oxford, 2005-2009 00004 00005 University of Oxford means the Chancellor, Masters and Scholars of the 00006 University of Oxford, having an administrative office at Wellington 00007 Square, Oxford OX1 2JD, UK. 00008 00009 This file is part of Chaste. 00010 00011 Chaste is free software: you can redistribute it and/or modify it 00012 under the terms of the GNU Lesser General Public License as published 00013 by the Free Software Foundation, either version 2.1 of the License, or 00014 (at your option) any later version. 00015 00016 Chaste is distributed in the hope that it will be useful, but WITHOUT 00017 ANY WARRANTY; without even the implied warranty of MERCHANTABILITY or 00018 FITNESS FOR A PARTICULAR PURPOSE. See the GNU Lesser General Public 00019 License for more details. The offer of Chaste under the terms of the 00020 License is subject to the License being interpreted in accordance with 00021 English Law and subject to any action against the University of Oxford 00022 being under the jurisdiction of the English Courts. 00023 00024 You should have received a copy of the GNU Lesser General Public License 00025 along with Chaste. If not, see <http://www.gnu.org/licenses/>. 00026 00027 */ 00028 #ifndef ABSTRACTODEBASEDCELLCYCLEMODEL_HPP_ 00029 #define ABSTRACTODEBASEDCELLCYCLEMODEL_HPP_ 00030 00031 #include <boost/serialization/access.hpp> 00032 #include <boost/serialization/is_abstract.hpp> 00033 #include <boost/serialization/base_object.hpp> 00034 00035 #include "AbstractCellCycleModel.hpp" 00036 #include "AbstractOdeSystem.hpp" 00037 00038 // Needs to be included last 00039 #include <boost/serialization/export.hpp> 00040 00047 class AbstractOdeBasedCellCycleModel : public AbstractCellCycleModel 00048 { 00049 private: 00050 00052 friend class boost::serialization::access; 00059 template<class Archive> 00060 void serialize(Archive & archive, const unsigned int version) 00061 { 00062 archive & boost::serialization::base_object<AbstractCellCycleModel>(*this); 00063 assert(mpOdeSystem!=NULL); 00064 archive & mpOdeSystem->rGetStateVariables(); 00065 archive & mLastTime; 00066 archive & mDivideTime; 00067 archive & mFinishedRunningOdes; 00068 archive & mG2PhaseStartTime; 00069 } 00070 00071 protected: 00072 00074 AbstractOdeSystem* mpOdeSystem; 00075 00077 double mLastTime; 00078 00080 double mDivideTime; 00081 00083 bool mFinishedRunningOdes; 00084 00086 double mG2PhaseStartTime; 00087 00088 public: 00089 00097 AbstractOdeBasedCellCycleModel(double lastTime = SimulationTime::Instance()->GetTime()); 00098 00102 virtual ~AbstractOdeBasedCellCycleModel(); 00103 00110 virtual void UpdateCellCyclePhase(); 00111 00119 virtual bool SolveOdeToTime(double currentTime)=0; 00120 00129 virtual double GetOdeStopTime()=0; 00130 00137 void SetBirthTime(double birthTime); 00138 00144 std::vector<double> GetProteinConcentrations() const; 00145 00153 void SetProteinConcentrationsForTestsOnly(double lastTime, std::vector<double> proteinConcentrations); 00154 00160 virtual void ResetForDivision(); 00161 }; 00162 00163 BOOST_IS_ABSTRACT(AbstractOdeBasedCellCycleModel) 00164 00165 #endif /*ABSTRACTODEBASEDCELLCYCLEMODEL_HPP_*/