AbstractWntOdeBasedCellCycleModel.hpp

00001 /*
00002 
00003 Copyright (C) University of Oxford, 2005-2009
00004 
00005 University of Oxford means the Chancellor, Masters and Scholars of the
00006 University of Oxford, having an administrative office at Wellington
00007 Square, Oxford OX1 2JD, UK.
00008 
00009 This file is part of Chaste.
00010 
00011 Chaste is free software: you can redistribute it and/or modify it
00012 under the terms of the GNU Lesser General Public License as published
00013 by the Free Software Foundation, either version 2.1 of the License, or
00014 (at your option) any later version.
00015 
00016 Chaste is distributed in the hope that it will be useful, but WITHOUT
00017 ANY WARRANTY; without even the implied warranty of MERCHANTABILITY or
00018 FITNESS FOR A PARTICULAR PURPOSE.  See the GNU Lesser General Public
00019 License for more details. The offer of Chaste under the terms of the
00020 License is subject to the License being interpreted in accordance with
00021 English Law and subject to any action against the University of Oxford
00022 being under the jurisdiction of the English Courts.
00023 
00024 You should have received a copy of the GNU Lesser General Public License
00025 along with Chaste. If not, see <http://www.gnu.org/licenses/>.
00026 
00027 */
00028 #ifndef ABSTRACTWNTODEBASEDCELLCYCLEMODEL_HPP_
00029 #define ABSTRACTWNTODEBASEDCELLCYCLEMODEL_HPP_
00030 
00031 #include <boost/serialization/access.hpp>
00032 #include <boost/serialization/is_abstract.hpp>
00033 #include <boost/serialization/base_object.hpp>
00034 
00035 #include "AbstractOdeBasedCellCycleModel.hpp"
00036 #include "RungeKutta4IvpOdeSolver.hpp"
00037 #include "CvodeAdaptor.hpp"
00038 
00039 // Needs to be included last
00040 #include <boost/serialization/export.hpp>
00041 
00054 class AbstractWntOdeBasedCellCycleModel : public AbstractOdeBasedCellCycleModel
00055 {
00056 private:
00057 
00059     friend class boost::serialization::access;
00066     template<class Archive>
00067     void serialize(Archive & archive, const unsigned int version)
00068     {
00069         archive & boost::serialization::base_object<AbstractOdeBasedCellCycleModel>(*this);
00070     }
00071 
00072 protected:
00073 
00074 #ifdef CHASTE_CVODE
00075 
00076     static CvodeAdaptor msSolver;
00077 #else
00078 
00079     static RungeKutta4IvpOdeSolver msSolver;
00080 #endif //CHASTE_CVODE
00081 
00087     AbstractWntOdeBasedCellCycleModel(double lastTime)
00088         : AbstractOdeBasedCellCycleModel(lastTime)
00089     {
00090 #ifdef CHASTE_CVODE
00091         msSolver.CheckForStoppingEvents();
00092         msSolver.SetMaxSteps(10000);
00093         //msSolver.SetTolerances(1e-6, 1e-8);
00094 #endif //CHASTE_CVODE
00095     }
00096 
00100     virtual double GetOdeStopTime();
00101 
00102 public:
00103 
00107     AbstractWntOdeBasedCellCycleModel();
00108 
00116     void ResetForDivision();
00117 
00124     void UpdateCellType();
00125 
00130     virtual void ChangeCellTypeDueToCurrentBetaCateninLevel()=0;
00131 
00132 };
00133 
00134 BOOST_IS_ABSTRACT(AbstractWntOdeBasedCellCycleModel)
00135 
00136 #endif /*ABSTRACTWNTODEBASEDCELLCYCLEMODEL_HPP_*/
00137 
00138 

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