00001 /* 00002 00003 Copyright (C) University of Oxford, 2005-2009 00004 00005 University of Oxford means the Chancellor, Masters and Scholars of the 00006 University of Oxford, having an administrative office at Wellington 00007 Square, Oxford OX1 2JD, UK. 00008 00009 This file is part of Chaste. 00010 00011 Chaste is free software: you can redistribute it and/or modify it 00012 under the terms of the GNU Lesser General Public License as published 00013 by the Free Software Foundation, either version 2.1 of the License, or 00014 (at your option) any later version. 00015 00016 Chaste is distributed in the hope that it will be useful, but WITHOUT 00017 ANY WARRANTY; without even the implied warranty of MERCHANTABILITY or 00018 FITNESS FOR A PARTICULAR PURPOSE. See the GNU Lesser General Public 00019 License for more details. The offer of Chaste under the terms of the 00020 License is subject to the License being interpreted in accordance with 00021 English Law and subject to any action against the University of Oxford 00022 being under the jurisdiction of the English Courts. 00023 00024 You should have received a copy of the GNU Lesser General Public License 00025 along with Chaste. If not, see <http://www.gnu.org/licenses/>. 00026 00027 */ 00028 #ifndef ABSTRACTWNTODEBASEDCELLCYCLEMODEL_HPP_ 00029 #define ABSTRACTWNTODEBASEDCELLCYCLEMODEL_HPP_ 00030 00031 #include <boost/serialization/access.hpp> 00032 #include <boost/serialization/is_abstract.hpp> 00033 #include <boost/serialization/base_object.hpp> 00034 00035 #include "AbstractOdeBasedCellCycleModel.hpp" 00036 #include "RungeKutta4IvpOdeSolver.hpp" 00037 #include "CvodeAdaptor.hpp" 00038 00039 // Needs to be included last 00040 #include <boost/serialization/export.hpp> 00041 00054 class AbstractWntOdeBasedCellCycleModel : public AbstractOdeBasedCellCycleModel 00055 { 00056 private: 00057 00059 friend class boost::serialization::access; 00066 template<class Archive> 00067 void serialize(Archive & archive, const unsigned int version) 00068 { 00069 archive & boost::serialization::base_object<AbstractOdeBasedCellCycleModel>(*this); 00070 } 00071 00072 protected: 00073 00074 #ifdef CHASTE_CVODE 00075 00076 static CvodeAdaptor msSolver; 00077 #else 00078 00079 static RungeKutta4IvpOdeSolver msSolver; 00080 #endif //CHASTE_CVODE 00081 00087 AbstractWntOdeBasedCellCycleModel(double lastTime) 00088 : AbstractOdeBasedCellCycleModel(lastTime) 00089 { 00090 #ifdef CHASTE_CVODE 00091 msSolver.CheckForStoppingEvents(); 00092 msSolver.SetMaxSteps(10000); 00093 //msSolver.SetTolerances(1e-6, 1e-8); 00094 #endif //CHASTE_CVODE 00095 } 00096 00100 virtual double GetOdeStopTime(); 00101 00102 public: 00103 00107 AbstractWntOdeBasedCellCycleModel(); 00108 00116 void ResetForDivision(); 00117 00124 void UpdateCellType(); 00125 00130 virtual void ChangeCellTypeDueToCurrentBetaCateninLevel()=0; 00131 00132 }; 00133 00134 BOOST_IS_ABSTRACT(AbstractWntOdeBasedCellCycleModel) 00135 00136 #endif /*ABSTRACTWNTODEBASEDCELLCYCLEMODEL_HPP_*/ 00137 00138