00001 /* 00002 00003 Copyright (C) University of Oxford, 2005-2009 00004 00005 University of Oxford means the Chancellor, Masters and Scholars of the 00006 University of Oxford, having an administrative office at Wellington 00007 Square, Oxford OX1 2JD, UK. 00008 00009 This file is part of Chaste. 00010 00011 Chaste is free software: you can redistribute it and/or modify it 00012 under the terms of the GNU Lesser General Public License as published 00013 by the Free Software Foundation, either version 2.1 of the License, or 00014 (at your option) any later version. 00015 00016 Chaste is distributed in the hope that it will be useful, but WITHOUT 00017 ANY WARRANTY; without even the implied warranty of MERCHANTABILITY or 00018 FITNESS FOR A PARTICULAR PURPOSE. See the GNU Lesser General Public 00019 License for more details. The offer of Chaste under the terms of the 00020 License is subject to the License being interpreted in accordance with 00021 English Law and subject to any action against the University of Oxford 00022 being under the jurisdiction of the English Courts. 00023 00024 You should have received a copy of the GNU Lesser General Public License 00025 along with Chaste. If not, see <http://www.gnu.org/licenses/>. 00026 00027 */ 00028 #include "SloughingCellKiller.hpp" 00029 #include "AbstractCellCentreBasedTissue.hpp" 00030 00031 SloughingCellKiller::SloughingCellKiller(AbstractTissue<2>* pCrypt, bool sloughSides) 00032 : AbstractCellKiller<2>(pCrypt), 00033 mSloughSides(sloughSides) 00034 { 00035 } 00036 00037 00038 bool SloughingCellKiller::GetSloughSides() const 00039 { 00040 return mSloughSides; 00041 } 00042 00043 00044 void SloughingCellKiller::TestAndLabelCellsForApoptosisOrDeath() 00045 { 00046 double crypt_length = CancerParameters::Instance()->GetCryptLength(); 00047 double crypt_width = CancerParameters::Instance()->GetCryptWidth(); 00048 00049 for (AbstractTissue<2>::Iterator cell_iter = this->mpTissue->Begin(); 00050 cell_iter != this->mpTissue->End(); 00051 ++cell_iter) 00052 { 00053 double x = this->mpTissue->GetLocationOfCellCentre(&(*cell_iter))[0]; 00054 double y = this->mpTissue->GetLocationOfCellCentre(&(*cell_iter))[1]; 00055 00056 if ( (y>crypt_length) || (mSloughSides && ((x<0.0) || (x>crypt_width))) ) 00057 { 00058 cell_iter->Kill(); 00059 } 00060 } 00061 }