StochasticWntCellCycleModel.hpp

00001 /*
00002 
00003 Copyright (C) University of Oxford, 2005-2009
00004 
00005 University of Oxford means the Chancellor, Masters and Scholars of the
00006 University of Oxford, having an administrative office at Wellington
00007 Square, Oxford OX1 2JD, UK.
00008 
00009 This file is part of Chaste.
00010 
00011 Chaste is free software: you can redistribute it and/or modify it
00012 under the terms of the GNU Lesser General Public License as published
00013 by the Free Software Foundation, either version 2.1 of the License, or
00014 (at your option) any later version.
00015 
00016 Chaste is distributed in the hope that it will be useful, but WITHOUT
00017 ANY WARRANTY; without even the implied warranty of MERCHANTABILITY or
00018 FITNESS FOR A PARTICULAR PURPOSE.  See the GNU Lesser General Public
00019 License for more details. The offer of Chaste under the terms of the
00020 License is subject to the License being interpreted in accordance with
00021 English Law and subject to any action against the University of Oxford
00022 being under the jurisdiction of the English Courts.
00023 
00024 You should have received a copy of the GNU Lesser General Public License
00025 along with Chaste. If not, see <http://www.gnu.org/licenses/>.
00026 
00027 */
00028 #ifndef STOCHASTICWNTCELLCYCLEMODEL_HPP_
00029 #define STOCHASTICWNTCELLCYCLEMODEL_HPP_
00030 
00031 #include <boost/serialization/access.hpp>
00032 #include <boost/serialization/base_object.hpp>
00033 
00034 #include "WntCellCycleModel.hpp"
00035 #include "RandomNumberGenerator.hpp"
00036 
00037 // Needs to be included last
00038 #include <boost/serialization/export.hpp>
00039 
00046 class StochasticWntCellCycleModel : public WntCellCycleModel
00047 {
00048 private:
00049 
00051     friend class boost::serialization::access;
00064     template<class Archive>
00065     void serialize(Archive & archive, const unsigned int version)
00066     {
00067         archive & boost::serialization::base_object<WntCellCycleModel>(*this);
00068 
00069         RandomNumberGenerator* p_gen = RandomNumberGenerator::Instance();
00070         archive & *p_gen;
00071         archive & p_gen;
00072 
00073         archive & mG2Duration;
00074     }
00075 
00077     double mG2Duration;
00078 
00090     void SetG2Duration();
00091 
00092 public:
00093 
00097     void InitialiseDaughterCell();
00098 
00106     void Initialise();
00107 
00112     void ResetForDivision();
00113 
00117     double GetG2Duration();
00118 
00122     StochasticWntCellCycleModel();
00123 
00137     StochasticWntCellCycleModel(AbstractOdeSystem* pParentOdeSystem,
00138                                 CellMutationState mutationState,
00139                                 double birthTime,
00140                                 double lastTime,
00141                                 bool inSG2MPhase,
00142                                 bool readyToDivide,
00143                                 double divideTime,
00144                                 double g2Duration);
00145 
00152     StochasticWntCellCycleModel(std::vector<double> parentProteinConcentrations,
00153                                 CellMutationState mutationState);
00154 
00164     AbstractCellCycleModel* CreateDaughterCellCycleModel();
00165 
00166 };
00167 
00168 
00169 // Declare identifier for the serializer
00170 BOOST_CLASS_EXPORT(StochasticWntCellCycleModel)
00171 
00172 namespace boost
00173 {
00174 namespace serialization
00175 {
00180 template<class Archive>
00181 inline void save_construct_data(
00182     Archive & ar, const StochasticWntCellCycleModel * t, const unsigned int file_version)
00183 {
00184 }
00185 
00190 template<class Archive>
00191 inline void load_construct_data(
00192     Archive & ar, StochasticWntCellCycleModel * t, const unsigned int file_version)
00193 {
00201     std::vector<double> state_vars;
00202     for (unsigned i=0; i<9; i++)
00203     {
00204         state_vars.push_back(0.0);
00205     }
00206 
00207     CellMutationState mutation_state = HEALTHY;
00208 
00209     ::new(t)StochasticWntCellCycleModel(state_vars, mutation_state);
00210 }
00211 }
00212 } // namespace
00213 
00214 #endif /*STOCHASTICWNTCELLCYCLEMODEL_HPP_*/

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