TysonNovakCellCycleModel.hpp

00001 /*
00002 
00003 Copyright (C) University of Oxford, 2005-2009
00004 
00005 University of Oxford means the Chancellor, Masters and Scholars of the
00006 University of Oxford, having an administrative office at Wellington
00007 Square, Oxford OX1 2JD, UK.
00008 
00009 This file is part of Chaste.
00010 
00011 Chaste is free software: you can redistribute it and/or modify it
00012 under the terms of the GNU Lesser General Public License as published
00013 by the Free Software Foundation, either version 2.1 of the License, or
00014 (at your option) any later version.
00015 
00016 Chaste is distributed in the hope that it will be useful, but WITHOUT
00017 ANY WARRANTY; without even the implied warranty of MERCHANTABILITY or
00018 FITNESS FOR A PARTICULAR PURPOSE.  See the GNU Lesser General Public
00019 License for more details. The offer of Chaste under the terms of the
00020 License is subject to the License being interpreted in accordance with
00021 English Law and subject to any action against the University of Oxford
00022 being under the jurisdiction of the English Courts.
00023 
00024 You should have received a copy of the GNU Lesser General Public License
00025 along with Chaste. If not, see <http://www.gnu.org/licenses/>.
00026 
00027 */
00028 #ifndef TYSONNOVAKCELLCYCLEMODEL_HPP_
00029 #define TYSONNOVAKCELLCYCLEMODEL_HPP_
00030 
00031 #include <boost/serialization/access.hpp>
00032 
00033 #include <iostream>
00034 
00035 #include "AbstractOdeBasedCellCycleModel.hpp"
00036 #include "TysonNovak2001OdeSystem.hpp"
00037 #include "BackwardEulerIvpOdeSolver.hpp"
00038 #include "CvodeAdaptor.hpp"
00039 #include "Exception.hpp"
00040 
00041 // Needs to be included last
00042 #include <boost/serialization/export.hpp>
00043 
00056 class TysonNovakCellCycleModel : public AbstractOdeBasedCellCycleModel
00057 {
00058 private:
00059 
00060 #ifdef CHASTE_CVODE
00061 
00062     static CvodeAdaptor msSolver;
00063 #else
00064 
00065     static BackwardEulerIvpOdeSolver msSolver;
00066 #endif  //CHASTE_CVODE
00067 
00074     TysonNovakCellCycleModel(std::vector<double> parentProteinConcentrations,
00075                              double divideTime);
00076 
00078     friend class boost::serialization::access;
00085     template<class Archive>
00086     void serialize(Archive & archive, const unsigned int version)
00087     {
00088         archive & boost::serialization::base_object<AbstractOdeBasedCellCycleModel>(*this);
00089     }
00090 
00091 public:
00092 
00096     TysonNovakCellCycleModel();
00097 
00102     void ResetForDivision();
00103 
00113     AbstractCellCycleModel* CreateDaughterCellCycleModel();
00114 
00121     bool SolveOdeToTime(double currentTime);
00122 
00128     double GetOdeStopTime();
00129 
00133     double GetSDuration();
00134 
00138     double GetG2Duration();
00139 
00143     double GetMDuration();
00144 
00148     void InitialiseDaughterCell();
00149 
00150 };
00151 
00152 
00153 // Declare identifier for the serializer
00154 BOOST_CLASS_EXPORT(TysonNovakCellCycleModel)
00155 
00156 
00157 #endif /*TYSONNOVAKCELLCYCLEMODEL_HPP_*/

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