WntCellCycleOdeSystem.hpp

/*

Copyright (C) University of Oxford, 2005-2009

University of Oxford means the Chancellor, Masters and Scholars of the
University of Oxford, having an administrative office at Wellington
Square, Oxford OX1 2JD, UK.

This file is part of Chaste.

Chaste is free software: you can redistribute it and/or modify it
under the terms of the GNU Lesser General Public License as published
by the Free Software Foundation, either version 2.1 of the License, or
(at your option) any later version.

Chaste is distributed in the hope that it will be useful, but WITHOUT
ANY WARRANTY; without even the implied warranty of MERCHANTABILITY or
FITNESS FOR A PARTICULAR PURPOSE.  See the GNU Lesser General Public
License for more details. The offer of Chaste under the terms of the
License is subject to the License being interpreted in accordance with
English Law and subject to any action against the University of Oxford
being under the jurisdiction of the English Courts.

You should have received a copy of the GNU Lesser General Public License
along with Chaste. If not, see <http://www.gnu.org/licenses/>.

*/
#ifndef WNTCELLCYCLEODESYSTEM_HPP_
#define WNTCELLCYCLEODESYSTEM_HPP_

#include <cmath>
#include <iostream>

#include "AbstractOdeSystem.hpp"
#include "CellMutationStates.hpp"

class WntCellCycleOdeSystem : public AbstractOdeSystem
{
private:

    double mk2d;
    double mk3d;
    double mk34d;
    double mk43d;
    double mk23d;
    double mad;
    double mJ11d;
    double mJ12d;
    double mJ13d;
    double mJ61d;
    double mJ62d;
    double mJ63d;
    double mKm1d;
    double mkpd;
    double mphi_r;
    double mphi_i;
    double mphi_j;
    double mphi_p;
    double ma2d;
    double ma3d;
    double ma4d;
    double ma5d;
    double mk16d;
    double mk61d;
    double mPhiE2F1;

    CellMutationState mMutationState;

public:

    WntCellCycleOdeSystem(double WntStimulus=0.0, const CellMutationState& rMutationState=HEALTHY);

    ~WntCellCycleOdeSystem();

    void Init();

    void SetMutationState(const CellMutationState &rMutationState);

    CellMutationState& rGetMutationState();

    void EvaluateYDerivatives(double time, const std::vector<double> &rY, std::vector<double> &rDY);

    bool CalculateStoppingEvent(double time, const std::vector<double> &rY);

    double CalculateRootFunction(double time, const std::vector<double> &rY);

};

#endif /*WNTCELLCYCLEODESYSTEM_HPP_*/

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