00001 /* 00002 00003 Copyright (C) University of Oxford, 2005-2010 00004 00005 University of Oxford means the Chancellor, Masters and Scholars of the 00006 University of Oxford, having an administrative office at Wellington 00007 Square, Oxford OX1 2JD, UK. 00008 00009 This file is part of Chaste. 00010 00011 Chaste is free software: you can redistribute it and/or modify it 00012 under the terms of the GNU Lesser General Public License as published 00013 by the Free Software Foundation, either version 2.1 of the License, or 00014 (at your option) any later version. 00015 00016 Chaste is distributed in the hope that it will be useful, but WITHOUT 00017 ANY WARRANTY; without even the implied warranty of MERCHANTABILITY or 00018 FITNESS FOR A PARTICULAR PURPOSE. See the GNU Lesser General Public 00019 License for more details. The offer of Chaste under the terms of the 00020 License is subject to the License being interpreted in accordance with 00021 English Law and subject to any action against the University of Oxford 00022 being under the jurisdiction of the English Courts. 00023 00024 You should have received a copy of the GNU Lesser General Public License 00025 along with Chaste. If not, see <http://www.gnu.org/licenses/>. 00026 00027 */ 00028 #ifndef WNTCONCENTRATION_HPP_ 00029 #define WNTCONCENTRATION_HPP_ 00030 00031 #include "ChasteSerialization.hpp" 00032 #include <boost/serialization/base_object.hpp> 00033 00034 #include <iostream> 00035 00036 #include "AbstractTissue.hpp" 00037 00044 typedef enum WntConcentrationType_ 00045 { 00046 NONE, 00047 LINEAR, 00048 RADIAL, 00049 EXPONENTIAL 00050 } WntConcentrationType; 00051 00052 00056 template<unsigned DIM> 00057 class WntConcentration 00058 { 00059 private: 00060 00062 static WntConcentration* mpInstance; 00063 00065 TissueConfig* mpTissueConfig; 00066 00073 WntConcentrationType mWntType; 00074 00078 AbstractTissue<DIM>* mpTissue; 00079 00083 bool mTypeSet; 00084 00088 double mConstantWntValueForTesting; 00089 00094 bool mUseConstantWntValueForTesting; 00095 00097 friend class boost::serialization::access; 00104 template<class Archive> 00105 void serialize(Archive & archive, const unsigned int version) 00106 { 00107 mpTissueConfig = TissueConfig::Instance(); 00108 archive & *mpTissueConfig; 00109 archive & mpTissueConfig; 00110 archive & mWntType; 00111 archive & mpTissue; 00112 archive & mTypeSet; 00113 archive & mConstantWntValueForTesting; 00114 archive & mUseConstantWntValueForTesting; 00115 } 00116 00117 protected: 00118 00122 WntConcentration(); 00123 00124 public: 00125 00132 static WntConcentration* Instance(); 00133 00137 virtual ~WntConcentration(); 00138 00143 static void Destroy(); 00144 00152 double GetWntLevel(double height); 00153 00162 double GetWntLevel(TissueCell& rCell); 00163 00170 c_vector<double, DIM> GetWntGradient(c_vector<double, DIM>& rLocation); 00171 00179 c_vector<double, DIM> GetWntGradient(TissueCell& rCell); 00180 00186 void SetTissue(AbstractTissue<DIM>& rTissue); 00187 00191 WntConcentrationType GetType(); 00192 00198 void SetType(WntConcentrationType type); 00199 00206 void SetConstantWntValueForTesting(double value); 00207 00218 bool IsWntSetUp(); 00219 00220 }; 00221 00222 #endif /*WNTCONCENTRATION_HPP_*/