00001 /* 00002 00003 Copyright (C) University of Oxford, 2005-2011 00004 00005 University of Oxford means the Chancellor, Masters and Scholars of the 00006 University of Oxford, having an administrative office at Wellington 00007 Square, Oxford OX1 2JD, UK. 00008 00009 This file is part of Chaste. 00010 00011 Chaste is free software: you can redistribute it and/or modify it 00012 under the terms of the GNU Lesser General Public License as published 00013 by the Free Software Foundation, either version 2.1 of the License, or 00014 (at your option) any later version. 00015 00016 Chaste is distributed in the hope that it will be useful, but WITHOUT 00017 ANY WARRANTY; without even the implied warranty of MERCHANTABILITY or 00018 FITNESS FOR A PARTICULAR PURPOSE. See the GNU Lesser General Public 00019 License for more details. The offer of Chaste under the terms of the 00020 License is subject to the License being interpreted in accordance with 00021 English Law and subject to any action against the University of Oxford 00022 being under the jurisdiction of the English Courts. 00023 00024 You should have received a copy of the GNU Lesser General Public License 00025 along with Chaste. If not, see <http://www.gnu.org/licenses/>. 00026 00027 */ 00028 #ifndef TYSONNOVAKCELLCYCLEMODEL_HPP_ 00029 #define TYSONNOVAKCELLCYCLEMODEL_HPP_ 00030 00031 #include "ChasteSerialization.hpp" 00032 #include <boost/serialization/base_object.hpp> 00033 00034 #include "AbstractOdeBasedCellCycleModel.hpp" 00035 #include "TysonNovak2001OdeSystem.hpp" 00036 00037 00047 class TysonNovakCellCycleModel : public AbstractOdeBasedCellCycleModel 00048 { 00049 private: 00050 00051 friend class TestOdeBasedCellCycleModels; 00052 00054 friend class boost::serialization::access; 00061 template<class Archive> 00062 void serialize(Archive & archive, const unsigned int version) 00063 { 00064 archive & boost::serialization::base_object<AbstractOdeBasedCellCycleModel>(*this); 00065 } 00066 00067 public: 00068 00074 TysonNovakCellCycleModel(boost::shared_ptr<AbstractCellCycleModelOdeSolver> pOdeSolver = boost::shared_ptr<AbstractCellCycleModelOdeSolver>()); 00075 00087 void Initialise(); 00088 00093 void ResetForDivision(); 00094 00099 AbstractCellCycleModel* CreateCellCycleModel(); 00100 00104 double GetSDuration(); 00105 00109 double GetG2Duration(); 00110 00114 double GetMDuration(); 00115 00119 void InitialiseDaughterCell(); 00120 00124 double GetAverageTransitCellCycleTime(); 00125 00129 double GetAverageStemCellCycleTime(); 00130 00134 bool CanCellTerminallyDifferentiate(); 00135 00141 virtual void OutputCellCycleModelParameters(out_stream& rParamsFile); 00142 }; 00143 00144 // Declare identifier for the serializer 00145 #include "SerializationExportWrapper.hpp" 00146 CHASTE_CLASS_EXPORT(TysonNovakCellCycleModel) 00147 #include "CellCycleModelOdeSolverExportWrapper.hpp" 00148 EXPORT_CELL_CYCLE_MODEL_ODE_SOLVER(TysonNovakCellCycleModel) 00149 00150 #endif /*TYSONNOVAKCELLCYCLEMODEL_HPP_*/