00001 /* 00002 00003 Copyright (C) University of Oxford, 2005-2011 00004 00005 University of Oxford means the Chancellor, Masters and Scholars of the 00006 University of Oxford, having an administrative office at Wellington 00007 Square, Oxford OX1 2JD, UK. 00008 00009 This file is part of Chaste. 00010 00011 Chaste is free software: you can redistribute it and/or modify it 00012 under the terms of the GNU Lesser General Public License as published 00013 by the Free Software Foundation, either version 2.1 of the License, or 00014 (at your option) any later version. 00015 00016 Chaste is distributed in the hope that it will be useful, but WITHOUT 00017 ANY WARRANTY; without even the implied warranty of MERCHANTABILITY or 00018 FITNESS FOR A PARTICULAR PURPOSE. See the GNU Lesser General Public 00019 License for more details. The offer of Chaste under the terms of the 00020 License is subject to the License being interpreted in accordance with 00021 English Law and subject to any action against the University of Oxford 00022 being under the jurisdiction of the English Courts. 00023 00024 You should have received a copy of the GNU Lesser General Public License 00025 along with Chaste. If not, see <http://www.gnu.org/licenses/>. 00026 00027 */ 00028 00029 #ifndef ABSTRACTCARDIACCELLINTERFACE_HPP_ 00030 #define ABSTRACTCARDIACCELLINTERFACE_HPP_ 00031 00032 #include <boost/shared_ptr.hpp> 00033 00034 #include "ChasteSerialization.hpp" 00035 #include "ClassIsAbstract.hpp" 00036 00037 #include "AbstractIvpOdeSolver.hpp" 00038 #include "AbstractStimulusFunction.hpp" 00039 #include "OdeSolution.hpp" 00040 #include "AbstractLookupTableCollection.hpp" 00041 00054 class AbstractCardiacCellInterface 00055 { 00056 public: 00069 AbstractCardiacCellInterface(boost::shared_ptr<AbstractIvpOdeSolver> pOdeSolver, 00070 unsigned voltageIndex, 00071 boost::shared_ptr<AbstractStimulusFunction> pIntracellularStimulus); 00072 00074 virtual ~AbstractCardiacCellInterface(); 00075 00081 virtual void SetTimestep(double dt)=0; 00082 00091 virtual void SolveAndUpdateState(double tStart, double tEnd)=0; 00092 00102 virtual OdeSolution Compute(double tStart, double tEnd, double tSamp=0.0)=0; 00103 00112 virtual void ComputeExceptVoltage(double tStart, double tEnd)=0; 00113 00139 virtual double GetIIonic(const std::vector<double>* pStateVariables=NULL)=0; 00140 00144 virtual void SetVoltage(double voltage)=0; 00145 00150 virtual double GetVoltage()=0; 00151 00158 unsigned GetVoltageIndex(); 00159 00165 void SetStimulusFunction(boost::shared_ptr<AbstractStimulusFunction> pStimulus); 00166 00172 double GetStimulus(double time); 00173 00180 void SetIntracellularStimulusFunction(boost::shared_ptr<AbstractStimulusFunction> pStimulus); 00181 00189 double GetIntracellularStimulus(double time); 00190 00197 double GetIntracellularAreaStimulus(double time); 00198 00207 void SetUsedInTissueSimulation(bool tissue=true); 00208 00215 virtual void UseCellMLDefaultStimulus(); 00216 00220 bool HasCellMLDefaultStimulus(); 00221 00229 virtual void VerifyStateVariables() 00230 { 00231 // See also #794. 00232 } 00233 00240 virtual AbstractLookupTableCollection* GetLookupTableCollection() 00241 { 00242 return NULL; 00243 } 00244 00248 boost::shared_ptr<AbstractStimulusFunction> GetStimulusFunction(); 00249 00256 const boost::shared_ptr<AbstractStimulusFunction> GetStimulusFunction() const; 00257 00264 const boost::shared_ptr<AbstractIvpOdeSolver> GetSolver() const; 00265 00266 protected: 00273 unsigned mVoltageIndex; 00274 00276 boost::shared_ptr<AbstractIvpOdeSolver> mpOdeSolver; 00277 00279 boost::shared_ptr<AbstractStimulusFunction> mpIntracellularStimulus; 00280 00286 bool mSetVoltageDerivativeToZero; 00287 00289 bool mIsUsedInTissue; 00290 00292 bool mHasDefaultStimulusFromCellML; 00293 00294 private: 00296 friend class boost::serialization::access; 00306 template<class Archive> 00307 void serialize(Archive & archive, const unsigned int version) 00308 { 00309 } 00310 }; 00311 00312 CLASS_IS_ABSTRACT(AbstractCardiacCellInterface) 00313 00314 00315 #endif /*ABSTRACTCARDIACCELLINTERFACE_HPP_*/