SimpleOxygenBasedCellCycleModel.hpp

00001 /*
00002 
00003 Copyright (C) University of Oxford, 2005-2011
00004 
00005 University of Oxford means the Chancellor, Masters and Scholars of the
00006 University of Oxford, having an administrative office at Wellington
00007 Square, Oxford OX1 2JD, UK.
00008 
00009 This file is part of Chaste.
00010 
00011 Chaste is free software: you can redistribute it and/or modify it
00012 under the terms of the GNU Lesser General Public License as published
00013 by the Free Software Foundation, either version 2.1 of the License, or
00014 (at your option) any later version.
00015 
00016 Chaste is distributed in the hope that it will be useful, but WITHOUT
00017 ANY WARRANTY; without even the implied warranty of MERCHANTABILITY or
00018 FITNESS FOR A PARTICULAR PURPOSE.  See the GNU Lesser General Public
00019 License for more details. The offer of Chaste under the terms of the
00020 License is subject to the License being interpreted in accordance with
00021 English Law and subject to any action against the University of Oxford
00022 being under the jurisdiction of the English Courts.
00023 
00024 You should have received a copy of the GNU Lesser General Public License
00025 along with Chaste. If not, see <http://www.gnu.org/licenses/>.
00026 
00027 */
00028 
00029 #ifndef SIMPLEOXYGENBASEDCELLCYCLEMODEL_HPP_
00030 #define SIMPLEOXYGENBASEDCELLCYCLEMODEL_HPP_
00031 
00032 #include "AbstractSimpleCellCycleModel.hpp"
00033 #include "CellwiseData.hpp"
00034 
00045 class SimpleOxygenBasedCellCycleModel : public AbstractSimpleCellCycleModel
00046 {
00047 private:
00048 
00049     friend class boost::serialization::access;
00050     template<class Archive>
00051     void serialize(Archive & archive, const unsigned int version)
00052     {
00053         archive & boost::serialization::base_object<AbstractSimpleCellCycleModel>(*this);
00054         archive & mTimeSpentInG1Phase;
00055         archive & mCurrentHypoxicDuration;
00056         archive & mCurrentHypoxiaOnsetTime;
00057         archive & mHypoxicConcentration;
00058         archive & mQuiescentConcentration;
00059         archive & mCriticalHypoxicDuration;
00060     }
00061 
00062 protected:
00063 
00068     double mTimeSpentInG1Phase;
00069 
00074     double mCurrentHypoxicDuration;
00075 
00079     double mCurrentHypoxiaOnsetTime;
00080 
00086     double mHypoxicConcentration;
00087 
00093     double mQuiescentConcentration;
00094 
00099     double mCriticalHypoxicDuration;
00100 
00101 public:
00102 
00106     SimpleOxygenBasedCellCycleModel();
00107 
00111     void UpdateCellCyclePhase();
00112 
00117     void UpdateHypoxicDuration();
00118 
00122     double GetCurrentHypoxicDuration();
00123 
00127     double GetCurrentHypoxiaOnsetTime();
00128 
00133     AbstractCellCycleModel* CreateCellCycleModel();
00134 
00138     double GetHypoxicConcentration();
00139 
00145     void SetHypoxicConcentration(double hypoxicConcentration);
00146 
00150     double GetQuiescentConcentration();
00151 
00157     void SetQuiescentConcentration(double quiescentConcentration);
00158 
00162     double GetCriticalHypoxicDuration();
00163 
00169     void SetCriticalHypoxicDuration(double criticalHypoxicDuration);
00170 
00176     void SetCurrentHypoxiaOnsetTime(double currentHypoxiaOnsetTime);
00177 
00183     virtual void OutputCellCycleModelParameters(out_stream& rParamsFile);
00184 };
00185 
00186 // Declare identifier for the serializer
00187 #include "SerializationExportWrapper.hpp"
00188 CHASTE_CLASS_EXPORT(SimpleOxygenBasedCellCycleModel)
00189 
00190 #endif /*SIMPLEOXYGENBASEDCELLCYCLEMODEL_HPP_*/

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