AbstractCardiacCellInterface.cpp

00001 /*
00002 
00003 Copyright (c) 2005-2014, University of Oxford.
00004 All rights reserved.
00005 
00006 University of Oxford means the Chancellor, Masters and Scholars of the
00007 University of Oxford, having an administrative office at Wellington
00008 Square, Oxford OX1 2JD, UK.
00009 
00010 This file is part of Chaste.
00011 
00012 Redistribution and use in source and binary forms, with or without
00013 modification, are permitted provided that the following conditions are met:
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00015    this list of conditions and the following disclaimer.
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00017    this list of conditions and the following disclaimer in the documentation
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00022 
00023 THIS SOFTWARE IS PROVIDED BY THE COPYRIGHT HOLDERS AND CONTRIBUTORS "AS IS"
00024 AND ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE
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00026 ARE DISCLAIMED. IN NO EVENT SHALL THE COPYRIGHT HOLDER OR CONTRIBUTORS BE
00027 LIABLE FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR
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00029 GOODS OR SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS INTERRUPTION)
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00033 
00034 */
00035 
00036 #include "HeartConfig.hpp" // First for Boost 1.33/PETSc 2.2
00037 
00038 #include "AbstractCardiacCellInterface.hpp"
00039 
00040 #include "Exception.hpp"
00041 
00042 
00043 AbstractCardiacCellInterface::AbstractCardiacCellInterface(
00044             boost::shared_ptr<AbstractIvpOdeSolver> pOdeSolver,
00045             unsigned voltageIndex,
00046             boost::shared_ptr<AbstractStimulusFunction> pIntracellularStimulus)
00047     : mVoltageIndex(voltageIndex),
00048       mpOdeSolver(pOdeSolver),
00049       mpIntracellularStimulus(pIntracellularStimulus),
00050       mSetVoltageDerivativeToZero(false),
00051       mIsUsedInTissue(false),
00052       mHasDefaultStimulusFromCellML(false),
00053       mFixedVoltage(DOUBLE_UNSET)
00054 {
00055 }
00056 
00057 
00058 AbstractCardiacCellInterface::~AbstractCardiacCellInterface()
00059 {
00060 }
00061 
00062 
00063 unsigned AbstractCardiacCellInterface::GetVoltageIndex()
00064 {
00065     return mVoltageIndex;
00066 }
00067 
00068 
00069 void AbstractCardiacCellInterface::SetStimulusFunction(boost::shared_ptr<AbstractStimulusFunction> pStimulus)
00070 {
00071     SetIntracellularStimulusFunction(pStimulus);
00072 }
00073 
00074 
00075 double AbstractCardiacCellInterface::GetStimulus(double time)
00076 {
00077     return GetIntracellularStimulus(time);
00078 }
00079 
00080 
00081 void AbstractCardiacCellInterface::SetIntracellularStimulusFunction(boost::shared_ptr<AbstractStimulusFunction> pStimulus)
00082 {
00083     mpIntracellularStimulus = pStimulus;
00084 }
00085 
00086 
00087 double AbstractCardiacCellInterface::GetIntracellularStimulus(double time)
00088 {
00089     return mpIntracellularStimulus->GetStimulus(time);
00090 }
00091 
00092 
00093 double AbstractCardiacCellInterface::GetIntracellularAreaStimulus(double time)
00094 {
00095     double stim;
00096     if (mIsUsedInTissue)
00097     {
00098         // Convert from uA/cm^3 to uA/cm^2 by dividing by Am
00099         stim = GetIntracellularStimulus(time) / HeartConfig::Instance()->GetSurfaceAreaToVolumeRatio();
00100     }
00101     else
00102     {
00103         stim = GetIntracellularStimulus(time);
00104     }
00105     return stim;
00106 }
00107 
00108 void AbstractCardiacCellInterface::SetUsedInTissueSimulation(bool tissue)
00109 {
00110     mIsUsedInTissue = tissue;
00111 }
00112 
00113 boost::shared_ptr<RegularStimulus> AbstractCardiacCellInterface::UseCellMLDefaultStimulus()
00114 {
00115     assert(!mHasDefaultStimulusFromCellML);
00116     EXCEPTION("This class has no default stimulus from CellML metadata.");
00117     return boost::shared_ptr<RegularStimulus>();
00118 }
00119 
00120 bool AbstractCardiacCellInterface::HasCellMLDefaultStimulus()
00121 {
00122     return mHasDefaultStimulusFromCellML;
00123 }
00124 
00125 boost::shared_ptr<AbstractStimulusFunction> AbstractCardiacCellInterface::GetStimulusFunction()
00126 {
00127     return mpIntracellularStimulus;
00128 }
00129 
00130 // Methods needed by boost serialization.
00131 const boost::shared_ptr<AbstractStimulusFunction> AbstractCardiacCellInterface::GetStimulusFunction() const
00132 {
00133     return mpIntracellularStimulus;
00134 }
00135 
00136 const boost::shared_ptr<AbstractIvpOdeSolver> AbstractCardiacCellInterface::GetSolver() const
00137 {
00138     return mpOdeSolver;
00139 }
00140 
00141 void AbstractCardiacCellInterface::SetVoltageDerivativeToZero(bool clamp)
00142 {
00143     mSetVoltageDerivativeToZero = clamp;
00144     if (clamp)
00145     {
00146         mFixedVoltage = GetVoltage();
00147     }
00148 }
00149 
00150 void AbstractCardiacCellInterface::SetFixedVoltage(double voltage)
00151 {
00152     mFixedVoltage = voltage;
00153 }
00154 
00155 double AbstractCardiacCellInterface::GetIntracellularCalciumConcentration()
00156 {
00157     EXCEPTION("AbstractCardiacCellInterface::GetIntracellularCalciumConcentration() called. "
00158               "Either model has no [Ca_i] or method has not been implemented yet");
00159 }
00160 
00161 

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