Swan2012AcinarUnit.cpp

00001 /*
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00034 */
00035 
00036 #include "Swan2012AcinarUnit.hpp"
00037 #include <cmath>
00038 #include <iostream>
00039 
00040 
00041 Swan2012AcinarUnit::Swan2012AcinarUnit() : mQ(0.0),
00042                                            mLambda(1.26),
00043                                            mDt(-1),
00044                                            mPaw(0.0),
00045                                            mPawOld(0.0),
00046                                            mPpl(0.0),
00047                                            mPplOld(0.0),
00048                                            mRaw(0.0),
00049                                            mA(0.433),
00050                                            mB(0.611),
00051                                            mXi(2.5),
00052                                            mV0(1.0)
00053 {
00054 
00055 }
00056 
00057 
00058 Swan2012AcinarUnit::~Swan2012AcinarUnit()
00059 {
00060 }
00061 
00062 void Swan2012AcinarUnit::SolveAndUpdateState(double tStart, double tEnd)
00063 {
00064     //Update stretch component
00065     double dPe = (mPaw - mPawOld) - (mPpl - mPplOld);
00066     double dLambda_dPe = 1.0/CalculateDerivativeStaticRecoilPressureByStrain();
00067 
00068     mLambda = mLambda + dLambda_dPe*dPe;
00069 
00070     //Update flow
00071     double c_a = CalculateAcinarTissueCompliance(); //Need to incorporate Ca(CW) too
00072 
00073     double dt = tEnd - tStart;
00074     double nu = (mPaw - mPawOld)/dt;
00075     double beta = (mPpl - mPplOld)/dt;
00076 
00077     mQ = c_a*(nu - beta) + (mQ - c_a*(nu - beta))*std::exp(-dt/(mRaw*c_a));
00078 }
00079 
00080 void Swan2012AcinarUnit::SetFlow(double flow)
00081 {
00082     mQ = flow;
00083 }
00084 
00085 double Swan2012AcinarUnit::GetFlow()
00086 {
00087     return mQ;
00088 }
00089 
00090 void Swan2012AcinarUnit::SetAirwayPressure(double pressure)
00091 {
00092     mPawOld = mPaw;
00093     mPaw = pressure;
00094 }
00095 
00096 void Swan2012AcinarUnit::SetPleuralPressure(double pressure)
00097 {
00098     mPplOld = mPpl;
00099     mPpl = pressure;
00100 }
00101 
00102 void Swan2012AcinarUnit::SetTerminalBronchioleResistance(double raw)
00103 {
00104     mRaw = raw;
00105 }
00106 
00107 double Swan2012AcinarUnit::GetStretchRatio()
00108 {
00109     return mLambda;
00110 }
00111 
00112 void Swan2012AcinarUnit::SetStretchRatio(double lambda)
00113 {
00114     mLambda = lambda;
00115 }
00116 
00117 
00118 double Swan2012AcinarUnit::GetVolume()
00119 {
00120     return mLambda*mLambda*mLambda*mV0;
00121 }
00122 
00123 void Swan2012AcinarUnit::SetUndeformedVolume(double v0)
00124 {
00125     mV0 = v0;
00126 }
00127 
00128 double Swan2012AcinarUnit::CalculateDerivativeVolumeByStrain()
00129 {
00130     return 3*mLambda*mLambda*mV0;
00131 }
00132 
00133 double Swan2012AcinarUnit::CalculateDerivativeStaticRecoilPressureByStrain()
00134 {
00135     double gamma = CalculateGamma();
00136     return ((3.0*mXi/2.0)*(3*mA + mB)*(3*mA + mB)*(mLambda*mLambda - 1)*(mLambda*mLambda - 1)*std::exp(gamma) +
00137             (mXi/2.0)*(3*mA + mB)*(mLambda*mLambda + 1)*std::exp(gamma)/(mLambda*mLambda));
00138 }
00139 
00140 double Swan2012AcinarUnit::CalculateGamma()
00141 {
00142     return (3.0/4.0)*(3*mA + mB)*(mLambda*mLambda - 1)*(mLambda*mLambda - 1);
00143 }
00144 
00145 double Swan2012AcinarUnit::CalculateAcinarTissueCompliance()
00146 {
00147     return CalculateDerivativeVolumeByStrain()/CalculateDerivativeStaticRecoilPressureByStrain();
00148 }
00149 

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