T2SwapCellKiller.cpp

00001 /*
00002 
00003 Copyright (c) 2005-2014, University of Oxford.
00004 All rights reserved.
00005 
00006 University of Oxford means the Chancellor, Masters and Scholars of the
00007 University of Oxford, having an administrative office at Wellington
00008 Square, Oxford OX1 2JD, UK.
00009 
00010 This file is part of Chaste.
00011 
00012 Redistribution and use in source and binary forms, with or without
00013 modification, are permitted provided that the following conditions are met:
00014  * Redistributions of source code must retain the above copyright notice,
00015    this list of conditions and the following disclaimer.
00016  * Redistributions in binary form must reproduce the above copyright notice,
00017    this list of conditions and the following disclaimer in the documentation
00018    and/or other materials provided with the distribution.
00019  * Neither the name of the University of Oxford nor the names of its
00020    contributors may be used to endorse or promote products derived from this
00021    software without specific prior written permission.
00022 
00023 THIS SOFTWARE IS PROVIDED BY THE COPYRIGHT HOLDERS AND CONTRIBUTORS "AS IS"
00024 AND ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE
00025 IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE
00026 ARE DISCLAIMED. IN NO EVENT SHALL THE COPYRIGHT HOLDER OR CONTRIBUTORS BE
00027 LIABLE FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR
00028 CONSEQUENTIAL DAMAGES (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF SUBSTITUTE
00029 GOODS OR SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS INTERRUPTION)
00030 HOWEVER CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT
00031 LIABILITY, OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY OUT
00032 OF THE USE OF THIS SOFTWARE, EVEN IF ADVISED OF THE POSSIBILITY OF SUCH DAMAGE.
00033 
00034 */
00035 
00036 #include "T2SwapCellKiller.hpp"
00037 
00038 template<unsigned DIM>
00039 T2SwapCellKiller<DIM>::T2SwapCellKiller(AbstractCellPopulation<DIM>* pCellPopulation)
00040     : AbstractCellKiller<DIM>(pCellPopulation)
00041 {
00042     // Throw an exception if the population is not a VertexBasedCellPopulation
00043     if (dynamic_cast<VertexBasedCellPopulation<DIM>*>(this->mpCellPopulation) == NULL)
00044     {
00045         EXCEPTION("A T2SwapCellKiller should only be used together with a VertexBasedCellPopulation.");
00046     }
00047 }
00048 
00049 template<unsigned DIM>
00050 void T2SwapCellKiller<DIM>::CheckAndLabelCellsForApoptosisOrDeath()
00051 {
00052     /*
00053      * This killer is different to other killers: it does not only check and label
00054      * cells for apoptosis or death, it actually carries out vertex rearrangements
00055      * and removes elements from the vertex mesh.
00056      *
00057      * We start with carrying out T2 swaps. Get the mesh and an element map.
00058      * The static_cast will work since we already know it's a VertexBasedCellPopulation.
00059      */
00060     MutableVertexMesh<DIM,DIM>& mesh = static_cast<MutableVertexMesh<DIM,DIM>&>(this->mpCellPopulation->rGetMesh());
00061     VertexElementMap element_map(mesh.GetNumAllElements());
00062 
00063     bool recheck_mesh = true;
00064     while (recheck_mesh == true)
00065     {
00066         // Note that whenever we call CheckForT2Swaps(), the element indices must run from zero up to mElements.size()-1
00067         recheck_mesh = mesh.CheckForT2Swaps(element_map);
00068     }
00069 
00070     /*
00071      * In the T2 swaps that happened above, vertex elements were removed from the
00072      * mesh but the associated cells are still there. Here we check which cells
00073      * underwent a T2 swap and label them as dead.
00074      */
00075     for (unsigned elem_index = 0; elem_index < element_map.Size(); elem_index++)
00076     {
00077         CellPtr p_cell = this->mpCellPopulation->GetCellUsingLocationIndex(elem_index);
00078         if (element_map.IsDeleted(elem_index))
00079         {
00080             p_cell->Kill();
00081         }
00082     }
00083 }
00084 
00085 template<unsigned DIM>
00086 void T2SwapCellKiller<DIM>::OutputCellKillerParameters(out_stream& rParamsFile)
00087 {
00088     // No parameters to output, so just call method on direct parent class
00089     AbstractCellKiller<DIM>::OutputCellKillerParameters(rParamsFile);
00090 }
00091 
00092 // Explicit instantiation
00093 template class T2SwapCellKiller<1>;
00094 template class T2SwapCellKiller<2>;
00095 template class T2SwapCellKiller<3>;
00096 
00097 // Serialization for Boost >= 1.36
00098 #include "SerializationExportWrapperForCpp.hpp"
00099 EXPORT_TEMPLATE_CLASS_SAME_DIMS(T2SwapCellKiller)

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