00001 /* 00002 00003 Copyright (c) 2005-2014, University of Oxford. 00004 All rights reserved. 00005 00006 University of Oxford means the Chancellor, Masters and Scholars of the 00007 University of Oxford, having an administrative office at Wellington 00008 Square, Oxford OX1 2JD, UK. 00009 00010 This file is part of Chaste. 00011 00012 Redistribution and use in source and binary forms, with or without 00013 modification, are permitted provided that the following conditions are met: 00014 * Redistributions of source code must retain the above copyright notice, 00015 this list of conditions and the following disclaimer. 00016 * Redistributions in binary form must reproduce the above copyright notice, 00017 this list of conditions and the following disclaimer in the documentation 00018 and/or other materials provided with the distribution. 00019 * Neither the name of the University of Oxford nor the names of its 00020 contributors may be used to endorse or promote products derived from this 00021 software without specific prior written permission. 00022 00023 THIS SOFTWARE IS PROVIDED BY THE COPYRIGHT HOLDERS AND CONTRIBUTORS "AS IS" 00024 AND ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE 00025 IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE 00026 ARE DISCLAIMED. IN NO EVENT SHALL THE COPYRIGHT HOLDER OR CONTRIBUTORS BE 00027 LIABLE FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR 00028 CONSEQUENTIAL DAMAGES (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF SUBSTITUTE 00029 GOODS OR SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS INTERRUPTION) 00030 HOWEVER CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT 00031 LIABILITY, OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY OUT 00032 OF THE USE OF THIS SOFTWARE, EVEN IF ADVISED OF THE POSSIBILITY OF SUCH DAMAGE. 00033 00034 */ 00035 00036 #include "T2SwapCellKiller.hpp" 00037 00038 template<unsigned DIM> 00039 T2SwapCellKiller<DIM>::T2SwapCellKiller(AbstractCellPopulation<DIM>* pCellPopulation) 00040 : AbstractCellKiller<DIM>(pCellPopulation) 00041 { 00042 // Throw an exception if the population is not a VertexBasedCellPopulation 00043 if (dynamic_cast<VertexBasedCellPopulation<DIM>*>(this->mpCellPopulation) == NULL) 00044 { 00045 EXCEPTION("A T2SwapCellKiller should only be used together with a VertexBasedCellPopulation."); 00046 } 00047 } 00048 00049 template<unsigned DIM> 00050 void T2SwapCellKiller<DIM>::CheckAndLabelCellsForApoptosisOrDeath() 00051 { 00052 /* 00053 * This killer is different to other killers: it does not only check and label 00054 * cells for apoptosis or death, it actually carries out vertex rearrangements 00055 * and removes elements from the vertex mesh. 00056 * 00057 * We start with carrying out T2 swaps. Get the mesh and an element map. 00058 * The static_cast will work since we already know it's a VertexBasedCellPopulation. 00059 */ 00060 MutableVertexMesh<DIM,DIM>& mesh = static_cast<MutableVertexMesh<DIM,DIM>&>(this->mpCellPopulation->rGetMesh()); 00061 VertexElementMap element_map(mesh.GetNumAllElements()); 00062 00063 bool recheck_mesh = true; 00064 while (recheck_mesh == true) 00065 { 00066 // Note that whenever we call CheckForT2Swaps(), the element indices must run from zero up to mElements.size()-1 00067 recheck_mesh = mesh.CheckForT2Swaps(element_map); 00068 } 00069 00070 /* 00071 * In the T2 swaps that happened above, vertex elements were removed from the 00072 * mesh but the associated cells are still there. Here we check which cells 00073 * underwent a T2 swap and label them as dead. 00074 */ 00075 for (unsigned elem_index = 0; elem_index < element_map.Size(); elem_index++) 00076 { 00077 CellPtr p_cell = this->mpCellPopulation->GetCellUsingLocationIndex(elem_index); 00078 if (element_map.IsDeleted(elem_index)) 00079 { 00080 p_cell->Kill(); 00081 } 00082 } 00083 } 00084 00085 template<unsigned DIM> 00086 void T2SwapCellKiller<DIM>::OutputCellKillerParameters(out_stream& rParamsFile) 00087 { 00088 // No parameters to output, so just call method on direct parent class 00089 AbstractCellKiller<DIM>::OutputCellKillerParameters(rParamsFile); 00090 } 00091 00092 // Explicit instantiation 00093 template class T2SwapCellKiller<1>; 00094 template class T2SwapCellKiller<2>; 00095 template class T2SwapCellKiller<3>; 00096 00097 // Serialization for Boost >= 1.36 00098 #include "SerializationExportWrapperForCpp.hpp" 00099 EXPORT_TEMPLATE_CLASS_SAME_DIMS(T2SwapCellKiller)
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