00001 /* 00002 00003 Copyright (c) 2005-2015, University of Oxford. 00004 All rights reserved. 00005 00006 University of Oxford means the Chancellor, Masters and Scholars of the 00007 University of Oxford, having an administrative office at Wellington 00008 Square, Oxford OX1 2JD, UK. 00009 00010 This file is part of Chaste. 00011 00012 Redistribution and use in source and binary forms, with or without 00013 modification, are permitted provided that the following conditions are met: 00014 * Redistributions of source code must retain the above copyright notice, 00015 this list of conditions and the following disclaimer. 00016 * Redistributions in binary form must reproduce the above copyright notice, 00017 this list of conditions and the following disclaimer in the documentation 00018 and/or other materials provided with the distribution. 00019 * Neither the name of the University of Oxford nor the names of its 00020 contributors may be used to endorse or promote products derived from this 00021 software without specific prior written permission. 00022 00023 THIS SOFTWARE IS PROVIDED BY THE COPYRIGHT HOLDERS AND CONTRIBUTORS "AS IS" 00024 AND ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE 00025 IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE 00026 ARE DISCLAIMED. IN NO EVENT SHALL THE COPYRIGHT HOLDER OR CONTRIBUTORS BE 00027 LIABLE FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR 00028 CONSEQUENTIAL DAMAGES (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF SUBSTITUTE 00029 GOODS OR SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS INTERRUPTION) 00030 HOWEVER CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT 00031 LIABILITY, OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY OUT 00032 OF THE USE OF THIS SOFTWARE, EVEN IF ADVISED OF THE POSSIBILITY OF SUCH DAMAGE. 00033 00034 */ 00035 00036 00037 #ifndef _CELLPROPERTIES_HPP_ 00038 #define _CELLPROPERTIES_HPP_ 00039 00040 #include <vector> 00041 00054 class CellProperties 00055 { 00056 private: 00058 const std::vector<double>& mrVoltage; 00060 const std::vector<double>& mrTime; 00061 00066 bool mUnfinishedActionPotentials; 00067 00073 double mThreshold; 00074 00076 std::vector<double> mOnsets; 00078 std::vector<double> mRestingValues; 00080 std::vector<double> mCycleLengths; 00082 std::vector<double> mPeakValues; 00084 std::vector<double> mMaxUpstrokeVelocities; 00086 std::vector<double> mTimesAtMaxUpstrokeVelocity; 00088 std::vector<unsigned> mCounterOfPlateauDepolarisations; 00089 00093 void CalculateProperties(); 00094 00107 std::vector<double> CalculateActionPotentialDurations(const double percentage); 00108 00113 void CheckExceededThreshold(void); 00114 00120 void CheckReturnedToThreshold(void); 00121 00122 public: 00123 00132 CellProperties(const std::vector<double> &rVoltage, 00133 const std::vector<double> &rTime, 00134 double threshold=-30.0) 00135 : mrVoltage(rVoltage), 00136 mrTime(rTime), 00137 mUnfinishedActionPotentials(false), 00138 mThreshold(threshold) 00139 { 00140 CalculateProperties(); 00141 } 00142 00148 std::vector<double> GetMaxUpstrokeVelocities(); 00149 00157 double GetLastMaxUpstrokeVelocity(); 00158 00165 double GetLastCompleteMaxUpstrokeVelocity(); 00166 00172 std::vector<double> GetTimesAtMaxUpstrokeVelocity(); 00173 00181 double GetTimeAtLastMaxUpstrokeVelocity(); 00182 00189 double GetTimeAtLastCompleteMaxUpstrokeVelocity(); 00190 00196 std::vector<double> GetCycleLengths(); 00197 00203 std::vector<double> GetPeakPotentials(); 00204 00210 double GetLastPeakPotential(); 00211 00217 double GetLastCompletePeakPotential(); 00218 00233 std::vector<double> GetRestingPotentials(); 00234 00241 double GetLastRestingPotential(); 00242 00251 std::vector<double> GetAllActionPotentialDurations(const double percentage); 00252 00262 double GetLastActionPotentialDuration(const double percentage); 00263 00269 std::vector<double> GetActionPotentialAmplitudes(); 00270 00276 double GetLastActionPotentialAmplitude(); 00277 00281 std::vector<unsigned> GetNumberOfAboveThresholdDepolarisationsForAllAps(); 00282 00286 unsigned GetNumberOfAboveThresholdDepolarisationsForLastAp(); 00287 }; 00288 00289 #endif //_CELLPROPERTIES_HPP_