GammaDistributedStochasticDurationCellCycleModel.cpp

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#include "GammaDistributedStochasticDurationCellCycleModel.hpp"
#include "Exception.hpp"
#include "StemCellProliferativeType.hpp"
#include "TransitCellProliferativeType.hpp"
#include "DifferentiatedCellProliferativeType.hpp"

GammaDistributedStochasticDurationCellCycleModel::GammaDistributedStochasticDurationCellCycleModel()
    : AbstractSimpleCellCycleModel(),
      mShape(DOUBLE_UNSET),
      mScale(DOUBLE_UNSET)
{
}

AbstractCellCycleModel* GammaDistributedStochasticDurationCellCycleModel::CreateCellCycleModel()
{
    // Create a new cell-cycle model
    GammaDistributedStochasticDurationCellCycleModel* p_model = new GammaDistributedStochasticDurationCellCycleModel();

    /*
     * Set each member variable of the new cell-cycle model that inherits
     * its value from the parent.
     *
     * Note 1: some of the new cell-cycle model's member variables (namely
     * mBirthTime, mCurrentCellCyclePhase, mReadyToDivide) will already have been
     * correctly initialized in its constructor.
     *
     * Note 2: one or more of the new cell-cycle model's member variables
     * may be set/overwritten as soon as InitialiseDaughterCell() is called on
     * the new cell-cycle model.
     *
     * Note 3: the member variable mDimension remains unset, since this cell-cycle
     * model does not need to know the spatial dimension, so if we were to call
     * SetDimension() on the new cell-cycle model an exception would be triggered;
     * hence we do not set this member variable.
     */
    p_model->SetBirthTime(mBirthTime);
    p_model->SetMinimumGapDuration(mMinimumGapDuration);
    p_model->SetStemCellG1Duration(mStemCellG1Duration);
    p_model->SetTransitCellG1Duration(mTransitCellG1Duration);
    p_model->SetSDuration(mSDuration);
    p_model->SetG2Duration(mG2Duration);
    p_model->SetMDuration(mMDuration);
    p_model->SetShape(mShape);
    p_model->SetScale(mScale);

    return p_model;
}

void GammaDistributedStochasticDurationCellCycleModel::SetG1Duration()
{
    if (    mpCell->GetCellProliferativeType()->IsType<StemCellProliferativeType>()
         || mpCell->GetCellProliferativeType()->IsType<TransitCellProliferativeType>() )
    {
        // Generate a gamma random number with mShape and mScale
        mG1Duration = RandomNumberGenerator::Instance()->GammaRandomDeviate(mShape, mScale);
    }
    else if (mpCell->GetCellProliferativeType()->IsType<DifferentiatedCellProliferativeType>())
    {
        mG1Duration = DBL_MAX;
    }
    else
    {
        NEVER_REACHED;
    }
}

void GammaDistributedStochasticDurationCellCycleModel::SetShape(double shape)
{
    mShape = shape;
}

void GammaDistributedStochasticDurationCellCycleModel::SetScale(double scale)
{
    mScale = scale;
}

double GammaDistributedStochasticDurationCellCycleModel::GetShape()
{
    return mShape;
}

double GammaDistributedStochasticDurationCellCycleModel::GetScale()
{
    return mScale;
}

void GammaDistributedStochasticDurationCellCycleModel::OutputCellCycleModelParameters(out_stream& rParamsFile)
{
    *rParamsFile << "\t\t\t<Shape>" << mShape << "</Shape>\n";
    *rParamsFile << "\t\t\t<Scale>" << mScale << "</Scale>\n";

    AbstractSimpleCellCycleModel::OutputCellCycleModelParameters(rParamsFile);
}

// Serialization for Boost >= 1.36
#include "SerializationExportWrapperForCpp.hpp"
CHASTE_CLASS_EXPORT(GammaDistributedStochasticDurationCellCycleModel)