00001 /* 00002 00003 Copyright (c) 2005-2015, University of Oxford. 00004 All rights reserved. 00005 00006 University of Oxford means the Chancellor, Masters and Scholars of the 00007 University of Oxford, having an administrative office at Wellington 00008 Square, Oxford OX1 2JD, UK. 00009 00010 This file is part of Chaste. 00011 00012 Redistribution and use in source and binary forms, with or without 00013 modification, are permitted provided that the following conditions are met: 00014 * Redistributions of source code must retain the above copyright notice, 00015 this list of conditions and the following disclaimer. 00016 * Redistributions in binary form must reproduce the above copyright notice, 00017 this list of conditions and the following disclaimer in the documentation 00018 and/or other materials provided with the distribution. 00019 * Neither the name of the University of Oxford nor the names of its 00020 contributors may be used to endorse or promote products derived from this 00021 software without specific prior written permission. 00022 00023 THIS SOFTWARE IS PROVIDED BY THE COPYRIGHT HOLDERS AND CONTRIBUTORS "AS IS" 00024 AND ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE 00025 IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE 00026 ARE DISCLAIMED. IN NO EVENT SHALL THE COPYRIGHT HOLDER OR CONTRIBUTORS BE 00027 LIABLE FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR 00028 CONSEQUENTIAL DAMAGES (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF SUBSTITUTE 00029 GOODS OR SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS INTERRUPTION) 00030 HOWEVER CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT 00031 LIABILITY, OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY OUT 00032 OF THE USE OF THIS SOFTWARE, EVEN IF ADVISED OF THE POSSIBILITY OF SUCH DAMAGE. 00033 00034 */ 00035 00036 #ifndef LINEARSPRINGWITHVARIABLESPRINGCONSTANTSFORCE_HPP 00037 #define LINEARSPRINGWITHVARIABLESPRINGCONSTANTSFORCE_HPP 00038 00039 #include "ChasteSerialization.hpp" 00040 #include <boost/serialization/base_object.hpp> 00041 00042 #include "GeneralisedLinearSpringForce.hpp" 00043 00047 template<unsigned DIM> 00048 class LinearSpringWithVariableSpringConstantsForce : public GeneralisedLinearSpringForce<DIM> 00049 { 00050 friend class TestLinearSpringWithVariableSpringConstantsForce; 00051 00052 private: 00053 00055 friend class boost::serialization::access; 00062 template<class Archive> 00063 void serialize(Archive & archive, const unsigned int version) 00064 { 00065 archive & boost::serialization::base_object<GeneralisedLinearSpringForce<DIM> >(*this); 00066 archive & mUseEdgeBasedSpringConstant; 00067 archive & mUseMutantSprings; 00068 archive & mMutantMutantMultiplier; 00069 archive & mNormalMutantMultiplier; 00070 archive & mUseBCatSprings; 00071 archive & mUseApoptoticSprings; 00072 archive & mBetaCatSpringScaler; 00073 archive & mApoptoticSpringTensionStiffness; 00074 archive & mApoptoticSpringCompressionStiffness; 00075 } 00076 00077 protected: 00078 00080 bool mUseEdgeBasedSpringConstant; 00081 00083 bool mUseMutantSprings; 00084 00086 double mMutantMutantMultiplier; 00087 00089 double mNormalMutantMultiplier; 00090 00092 bool mUseBCatSprings; 00093 00095 bool mUseApoptoticSprings; 00096 00098 double mBetaCatSpringScaler; 00099 00101 double mApoptoticSpringTensionStiffness; 00102 00104 double mApoptoticSpringCompressionStiffness; 00105 00106 public: 00107 00111 LinearSpringWithVariableSpringConstantsForce(); 00112 00116 virtual ~LinearSpringWithVariableSpringConstantsForce(); 00117 00123 void SetEdgeBasedSpringConstant(bool useEdgeBasedSpringConstant); 00124 00133 void SetMutantSprings(bool useMutantSprings, double mutantMutantMultiplier=2, double normalMutantMultiplier=1.5); 00134 00140 void SetBetaCateninSprings(bool useBCatSprings); 00141 00147 void SetApoptoticSprings(bool useApoptoticSprings); 00148 00162 double VariableSpringConstantMultiplicationFactor(unsigned nodeAGlobalIndex, 00163 unsigned nodeBGlobalIndex, 00164 AbstractCellPopulation<DIM>& rCellPopulation, 00165 bool isCloserThanRestLength); 00166 00172 void AddForceContribution(AbstractCellPopulation<DIM>& rCellPopulation); 00173 00177 double GetBetaCatSpringScaler(); 00178 00184 void SetBetaCatSpringScaler(double betaCatSpringScaler); 00185 00189 double GetApoptoticSpringTensionStiffness(); 00190 00196 void SetApoptoticSpringTensionStiffness(double apoptoticSpringTensionStiffness); 00197 00201 double GetApoptoticSpringCompressionStiffness(); 00202 00208 void SetApoptoticSpringCompressionStiffness(double apoptoticSpringCompressionStiffness); 00209 00218 virtual void OutputForceParameters(out_stream& rParamsFile); 00219 }; 00220 00221 #include "SerializationExportWrapper.hpp" 00222 00223 EXPORT_TEMPLATE_CLASS_SAME_DIMS(LinearSpringWithVariableSpringConstantsForce) 00224 00225 00226 #endif /*LINEARSPRINGWITHVARIABLESPRINGCONSTANTSFORCE_HPP*/