SimpleOxygenBasedCellCycleModel.hpp

00001 /*
00002 
00003 Copyright (c) 2005-2015, University of Oxford.
00004 All rights reserved.
00005 
00006 University of Oxford means the Chancellor, Masters and Scholars of the
00007 University of Oxford, having an administrative office at Wellington
00008 Square, Oxford OX1 2JD, UK.
00009 
00010 This file is part of Chaste.
00011 
00012 Redistribution and use in source and binary forms, with or without
00013 modification, are permitted provided that the following conditions are met:
00014  * Redistributions of source code must retain the above copyright notice,
00015    this list of conditions and the following disclaimer.
00016  * Redistributions in binary form must reproduce the above copyright notice,
00017    this list of conditions and the following disclaimer in the documentation
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00019  * Neither the name of the University of Oxford nor the names of its
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00022 
00023 THIS SOFTWARE IS PROVIDED BY THE COPYRIGHT HOLDERS AND CONTRIBUTORS "AS IS"
00024 AND ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE
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00026 ARE DISCLAIMED. IN NO EVENT SHALL THE COPYRIGHT HOLDER OR CONTRIBUTORS BE
00027 LIABLE FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR
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00029 GOODS OR SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS INTERRUPTION)
00030 HOWEVER CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT
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00034 */
00035 
00036 #ifndef SIMPLEOXYGENBASEDCELLCYCLEMODEL_HPP_
00037 #define SIMPLEOXYGENBASEDCELLCYCLEMODEL_HPP_
00038 
00039 #include "AbstractSimpleCellCycleModel.hpp"
00040 
00051 class SimpleOxygenBasedCellCycleModel : public AbstractSimpleCellCycleModel
00052 {
00053 private:
00054 
00055     friend class boost::serialization::access;
00061     template<class Archive>
00062     void serialize(Archive & archive, const unsigned int version)
00063     {
00064         archive & boost::serialization::base_object<AbstractSimpleCellCycleModel>(*this);
00065         archive & mCurrentHypoxicDuration;
00066         archive & mCurrentHypoxiaOnsetTime;
00067         archive & mHypoxicConcentration;
00068         archive & mQuiescentConcentration;
00069         archive & mCriticalHypoxicDuration;
00070     }
00071 
00072 protected:
00073 
00078     double mCurrentHypoxicDuration;
00079 
00083     double mCurrentHypoxiaOnsetTime;
00084 
00090     double mHypoxicConcentration;
00091 
00097     double mQuiescentConcentration;
00098 
00103     double mCriticalHypoxicDuration;
00104 
00105 public:
00106 
00110     SimpleOxygenBasedCellCycleModel();
00111 
00115     void UpdateCellCyclePhase();
00116 
00121     void UpdateHypoxicDuration();
00122 
00126     double GetCurrentHypoxicDuration();
00127 
00131     double GetCurrentHypoxiaOnsetTime();
00132 
00139     AbstractCellCycleModel* CreateCellCycleModel();
00140 
00144     double GetHypoxicConcentration();
00145 
00151     void SetHypoxicConcentration(double hypoxicConcentration);
00152 
00156     double GetQuiescentConcentration();
00157 
00163     void SetQuiescentConcentration(double quiescentConcentration);
00164 
00168     double GetCriticalHypoxicDuration();
00169 
00175     void SetCriticalHypoxicDuration(double criticalHypoxicDuration);
00176 
00182     void SetCurrentHypoxiaOnsetTime(double currentHypoxiaOnsetTime);
00183 
00189     virtual void OutputCellCycleModelParameters(out_stream& rParamsFile);
00190 };
00191 
00192 // Declare identifier for the serializer
00193 #include "SerializationExportWrapper.hpp"
00194 CHASTE_CLASS_EXPORT(SimpleOxygenBasedCellCycleModel)
00195 
00196 #endif /*SIMPLEOXYGENBASEDCELLCYCLEMODEL_HPP_*/

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