StochasticDurationCellCycleModel.cpp

00001 /*
00002 
00003 Copyright (c) 2005-2015, University of Oxford.
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00034 */
00035 
00036 #include "StochasticDurationCellCycleModel.hpp"
00037 #include "Exception.hpp"
00038 #include "StemCellProliferativeType.hpp"
00039 #include "TransitCellProliferativeType.hpp"
00040 #include "DifferentiatedCellProliferativeType.hpp"
00041 
00042 StochasticDurationCellCycleModel::StochasticDurationCellCycleModel()
00043     : AbstractSimpleCellCycleModel()
00044 {
00045 }
00046 
00047 AbstractCellCycleModel* StochasticDurationCellCycleModel::CreateCellCycleModel()
00048 {
00049     // Create a new cell-cycle model
00050     StochasticDurationCellCycleModel* p_model = new StochasticDurationCellCycleModel();
00051 
00052     /*
00053      * Set each member variable of the new cell-cycle model that inherits
00054      * its value from the parent.
00055      *
00056      * Note 1: some of the new cell-cycle model's member variables (namely
00057      * mBirthTime, mCurrentCellCyclePhase, mReadyToDivide) will already have been
00058      * correctly initialized in its constructor.
00059      *
00060      * Note 2: one or more of the new cell-cycle model's member variables
00061      * may be set/overwritten as soon as InitialiseDaughterCell() is called on
00062      * the new cell-cycle model.
00063      *
00064      * Note 3: the member variable mDimension remains unset, since this cell-cycle
00065      * model does not need to know the spatial dimension, so if we were to call
00066      * SetDimension() on the new cell-cycle model an exception would be triggered;
00067      * hence we do not set this member variable.
00068      */
00069     p_model->SetBirthTime(mBirthTime);
00070     p_model->SetMinimumGapDuration(mMinimumGapDuration);
00071     p_model->SetStemCellG1Duration(mStemCellG1Duration);
00072     p_model->SetTransitCellG1Duration(mTransitCellG1Duration);
00073     p_model->SetSDuration(mSDuration);
00074     p_model->SetG2Duration(mG2Duration);
00075     p_model->SetMDuration(mMDuration);
00076 
00077     return p_model;
00078 }
00079 
00080 void StochasticDurationCellCycleModel::SetG1Duration()
00081 {
00082     RandomNumberGenerator* p_gen = RandomNumberGenerator::Instance();
00083 
00084     if (mpCell->GetCellProliferativeType()->IsType<StemCellProliferativeType>())
00085     {
00086         mG1Duration = GetStemCellG1Duration() + 2*p_gen->ranf(); // U[0,2]
00087     }
00088     else if (mpCell->GetCellProliferativeType()->IsType<TransitCellProliferativeType>())
00089     {
00090         mG1Duration = GetTransitCellG1Duration() + 2*p_gen->ranf(); // U[0,2]
00091     }
00092     else if (mpCell->GetCellProliferativeType()->IsType<DifferentiatedCellProliferativeType>())
00093     {
00094         mG1Duration = DBL_MAX;
00095     }
00096     else
00097     {
00098         NEVER_REACHED;
00099     }
00100 }
00101 
00102 void StochasticDurationCellCycleModel::OutputCellCycleModelParameters(out_stream& rParamsFile)
00103 {
00104     // No new parameters to output, so just call method on direct parent class
00105     AbstractSimpleCellCycleModel::OutputCellCycleModelParameters(rParamsFile);
00106 }
00107 
00108 // Serialization for Boost >= 1.36
00109 #include "SerializationExportWrapperForCpp.hpp"
00110 CHASTE_CLASS_EXPORT(StochasticDurationCellCycleModel)

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