AbstractCellCycleModel.hpp

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*/
 
#ifndef ABSTRACTCELLCYCLEMODEL_HPP_
#define ABSTRACTCELLCYCLEMODEL_HPP_
 
#include "ChasteSerialization.hpp"
#include "ClassIsAbstract.hpp"
#include "Identifiable.hpp"
 
#include <boost/serialization/base_object.hpp>
 
#include <vector>
 
#include "OutputFileHandler.hpp"
#include "CellCyclePhases.hpp"
#include "SimulationTime.hpp"
#include "Cell.hpp"
 
class Cell; // Circular definition (cells need to know about cycle models and vice-versa)
typedef boost::shared_ptr<Cell> CellPtr;
 
class AbstractCellCycleModel : public Identifiable
{
private:
 
    friend class boost::serialization::access;
    template<class Archive>
    void serialize(Archive & archive, const unsigned int version)
    {
        // Make sure the SimulationTime singleton gets saved too
        SerializableSingleton<SimulationTime>* p_time_wrapper = SimulationTime::Instance()->GetSerializationWrapper();
        archive & p_time_wrapper;
 
        // DO NOT archive & mpCell; -- The CellCycleModel is only ever archived from the Cell
        // which knows this and it is handled in the load_construct of Cell.
        archive & mBirthTime;
        archive & mReadyToDivide;
        archive & mDimension;
    }
 
    AbstractCellCycleModel& operator=(const AbstractCellCycleModel&);
 
protected:
 
    CellPtr mpCell;
 
    double mBirthTime;
 
    bool mReadyToDivide;
 
    unsigned mDimension;
 
    AbstractCellCycleModel(const AbstractCellCycleModel& rModel);
 
public:
 
    AbstractCellCycleModel();
 
    virtual ~AbstractCellCycleModel();
 
    void SetCell(CellPtr pCell);
 
    virtual void Initialise();
 
    virtual void InitialiseDaughterCell();
 
    CellPtr GetCell();
 
    virtual void SetBirthTime(double birthTime);
 
    void SetDimension(unsigned dimension);
 
    unsigned GetDimension() const;
 
    double GetBirthTime() const;
 
    double GetAge();
 
    virtual bool ReadyToDivide()=0;
 
    virtual void ResetForDivision();
 
    virtual AbstractCellCycleModel* CreateCellCycleModel()=0;
 
    virtual bool CanCellTerminallyDifferentiate();
 
    virtual double GetAverageTransitCellCycleTime()=0;
 
    virtual double GetAverageStemCellCycleTime()=0;
 
    void OutputCellCycleModelInfo(out_stream& rParamsFile);
 
    virtual void OutputCellCycleModelParameters(out_stream& rParamsFile)=0;
};
 
CLASS_IS_ABSTRACT(AbstractCellCycleModel)
 
#endif /*ABSTRACTCELLCYCLEMODEL_HPP_*/