00001 /* 00002 00003 Copyright (C) University of Oxford, 2005-2009 00004 00005 University of Oxford means the Chancellor, Masters and Scholars of the 00006 University of Oxford, having an administrative office at Wellington 00007 Square, Oxford OX1 2JD, UK. 00008 00009 This file is part of Chaste. 00010 00011 Chaste is free software: you can redistribute it and/or modify it 00012 under the terms of the GNU Lesser General Public License as published 00013 by the Free Software Foundation, either version 2.1 of the License, or 00014 (at your option) any later version. 00015 00016 Chaste is distributed in the hope that it will be useful, but WITHOUT 00017 ANY WARRANTY; without even the implied warranty of MERCHANTABILITY or 00018 FITNESS FOR A PARTICULAR PURPOSE. See the GNU Lesser General Public 00019 License for more details. The offer of Chaste under the terms of the 00020 License is subject to the License being interpreted in accordance with 00021 English Law and subject to any action against the University of Oxford 00022 being under the jurisdiction of the English Courts. 00023 00024 You should have received a copy of the GNU Lesser General Public License 00025 along with Chaste. If not, see <http://www.gnu.org/licenses/>. 00026 00027 */ 00028 #include "AbstractSimpleGenerationBasedCellCycleModel.hpp" 00029 00030 00031 AbstractSimpleGenerationBasedCellCycleModel::AbstractSimpleGenerationBasedCellCycleModel() 00032 : AbstractSimpleCellCycleModel(), 00033 mGeneration(0) 00034 { 00035 } 00036 00037 void AbstractSimpleGenerationBasedCellCycleModel::ResetForDivision() 00038 { 00039 mGeneration++; 00040 if (mGeneration > TissueConfig::Instance()->GetMaxTransitGenerations()) 00041 { 00042 mpCell->SetCellType(DIFFERENTIATED); 00043 } 00044 if (mpCell->GetCellType() == STEM) 00045 { 00046 mGeneration = 0; 00047 } 00048 AbstractSimpleCellCycleModel::ResetForDivision(); 00049 } 00050 00051 00052 void AbstractSimpleGenerationBasedCellCycleModel::InitialiseDaughterCell() 00053 { 00054 /* 00055 * If the parent cell is a stem cell then its generation was reset 00056 * to zero when ResetForDivision() was called. The daughter cell's 00057 * generation must therefore be incremented here. 00058 */ 00059 if (mGeneration == 0) 00060 { 00061 mGeneration = 1; 00062 } 00063 /* 00064 * In generation-based cell cycle models, the daughter cell 00065 * is always of type transit or differentiated. 00066 */ 00067 mpCell->SetCellType(TRANSIT); 00068 if (mGeneration > TissueConfig::Instance()->GetMaxTransitGenerations()) 00069 { 00070 mpCell->SetCellType(DIFFERENTIATED); 00071 } 00072 AbstractSimpleCellCycleModel::InitialiseDaughterCell(); 00073 } 00074 00075 00076 void AbstractSimpleGenerationBasedCellCycleModel::SetGeneration(unsigned generation) 00077 { 00078 mGeneration = generation; 00079 } 00080 00081 00082 unsigned AbstractSimpleGenerationBasedCellCycleModel::GetGeneration() const 00083 { 00084 return mGeneration; 00085 }