00001 /* 00002 00003 Copyright (C) University of Oxford, 2005-2010 00004 00005 University of Oxford means the Chancellor, Masters and Scholars of the 00006 University of Oxford, having an administrative office at Wellington 00007 Square, Oxford OX1 2JD, UK. 00008 00009 This file is part of Chaste. 00010 00011 Chaste is free software: you can redistribute it and/or modify it 00012 under the terms of the GNU Lesser General Public License as published 00013 by the Free Software Foundation, either version 2.1 of the License, or 00014 (at your option) any later version. 00015 00016 Chaste is distributed in the hope that it will be useful, but WITHOUT 00017 ANY WARRANTY; without even the implied warranty of MERCHANTABILITY or 00018 FITNESS FOR A PARTICULAR PURPOSE. See the GNU Lesser General Public 00019 License for more details. The offer of Chaste under the terms of the 00020 License is subject to the License being interpreted in accordance with 00021 English Law and subject to any action against the University of Oxford 00022 being under the jurisdiction of the English Courts. 00023 00024 You should have received a copy of the GNU Lesser General Public License 00025 along with Chaste. If not, see <http://www.gnu.org/licenses/>. 00026 00027 */ 00028 #ifndef ABSTRACTODEBASEDCELLCYCLEMODEL_HPP_ 00029 #define ABSTRACTODEBASEDCELLCYCLEMODEL_HPP_ 00030 00031 #include "ChasteSerialization.hpp" 00032 #include "ClassIsAbstract.hpp" 00033 #include <boost/serialization/base_object.hpp> 00034 00035 #include "AbstractCellCycleModel.hpp" 00036 #include "AbstractOdeSystem.hpp" 00037 00044 class AbstractOdeBasedCellCycleModel : public AbstractCellCycleModel 00045 { 00046 private: 00047 00049 friend class boost::serialization::access; 00056 template<class Archive> 00057 void serialize(Archive & archive, const unsigned int version) 00058 { 00059 archive & boost::serialization::base_object<AbstractCellCycleModel>(*this); 00060 assert(mpOdeSystem!=NULL); 00061 archive & mpOdeSystem->rGetStateVariables(); 00062 archive & mLastTime; 00063 archive & mDivideTime; 00064 archive & mFinishedRunningOdes; 00065 archive & mG2PhaseStartTime; 00066 } 00067 00068 protected: 00069 00071 AbstractOdeSystem* mpOdeSystem; 00072 00074 double mLastTime; 00075 00077 double mDivideTime; 00078 00080 bool mFinishedRunningOdes; 00081 00083 double mG2PhaseStartTime; 00084 00085 public: 00086 00094 AbstractOdeBasedCellCycleModel(double lastTime = SimulationTime::Instance()->GetTime()); 00095 00106 AbstractOdeBasedCellCycleModel(const AbstractOdeBasedCellCycleModel& rOtherModel); 00107 00111 virtual ~AbstractOdeBasedCellCycleModel(); 00112 00119 virtual void UpdateCellCyclePhase(); 00120 00128 virtual bool SolveOdeToTime(double currentTime)=0; 00129 00138 virtual double GetOdeStopTime()=0; 00139 00146 void SetBirthTime(double birthTime); 00147 00153 std::vector<double> GetProteinConcentrations() const; 00154 00162 void SetProteinConcentrationsForTestsOnly(double lastTime, std::vector<double> proteinConcentrations); 00163 00169 virtual void ResetForDivision(); 00170 }; 00171 00172 CLASS_IS_ABSTRACT(AbstractOdeBasedCellCycleModel) 00173 00174 #endif /*ABSTRACTODEBASEDCELLCYCLEMODEL_HPP_*/