LuoRudyIModel1991OdeSystem.hpp

00001 /*
00002 
00003 Copyright (C) University of Oxford, 2005-2010
00004 
00005 University of Oxford means the Chancellor, Masters and Scholars of the
00006 University of Oxford, having an administrative office at Wellington
00007 Square, Oxford OX1 2JD, UK.
00008 
00009 This file is part of Chaste.
00010 
00011 Chaste is free software: you can redistribute it and/or modify it
00012 under the terms of the GNU Lesser General Public License as published
00013 by the Free Software Foundation, either version 2.1 of the License, or
00014 (at your option) any later version.
00015 
00016 Chaste is distributed in the hope that it will be useful, but WITHOUT
00017 ANY WARRANTY; without even the implied warranty of MERCHANTABILITY or
00018 FITNESS FOR A PARTICULAR PURPOSE.  See the GNU Lesser General Public
00019 License for more details. The offer of Chaste under the terms of the
00020 License is subject to the License being interpreted in accordance with
00021 English Law and subject to any action against the University of Oxford
00022 being under the jurisdiction of the English Courts.
00023 
00024 You should have received a copy of the GNU Lesser General Public License
00025 along with Chaste. If not, see <http://www.gnu.org/licenses/>.
00026 
00027 */
00028 #ifndef _LUORUDYIMODEL1991ODESYSTEM_HPP_
00029 #define _LUORUDYIMODEL1991ODESYSTEM_HPP_
00030 
00031 #include "ChasteSerialization.hpp"
00032 #include <boost/serialization/base_object.hpp>
00033 
00034 #include "AbstractCardiacCell.hpp"
00035 #include "AbstractStimulusFunction.hpp"
00036 #include <vector>
00037 
00041 class LuoRudyIModel1991OdeSystem : public AbstractCardiacCell
00042 {
00043 private:
00045     friend class boost::serialization::access;
00052     template<class Archive>
00053     void serialize(Archive & archive, const unsigned int version)
00054     {
00055         archive & boost::serialization::base_object<AbstractCardiacCell>(*this);
00056     }
00057 
00061     static const double membrane_C;
00063     static const double membrane_F;
00065     static const double membrane_R;
00067     static const double membrane_T;
00069     static const double background_current_E_b;
00071     static const double background_current_g_b;
00073     static const double fast_sodium_current_g_Na;
00075     static const double ionic_concentrations_Ki;
00077     static const double ionic_concentrations_Ko;
00079     static const double ionic_concentrations_Nai;
00081     static const double ionic_concentrations_Nao;
00083     static const double plateau_potassium_current_g_Kp;
00085     static const double time_dependent_potassium_current_PR_NaK;
00086 
00088     double fast_sodium_current_E_Na;
00089 
00095     void VerifyStateVariables();
00096 
00097 public:
00104     LuoRudyIModel1991OdeSystem(boost::shared_ptr<AbstractIvpOdeSolver> pSolver,
00105                                boost::shared_ptr<AbstractStimulusFunction> pIntracellularStimulus);
00106 
00110     ~LuoRudyIModel1991OdeSystem();
00111 
00121     void EvaluateYDerivatives(double time, const std::vector<double> &rY, std::vector<double> &rDY);
00122 
00128     double GetIIonic();
00129 
00135     double GetIntracellularCalciumConcentration();
00136 };
00137 
00138 #include "SerializationExportWrapper.hpp"
00139 CHASTE_CLASS_EXPORT(LuoRudyIModel1991OdeSystem);
00140 
00141 namespace boost
00142 {
00143 namespace serialization
00144 {
00149 template<class Archive>
00150 inline void save_construct_data(
00151     Archive & ar, const LuoRudyIModel1991OdeSystem * t, const unsigned int file_version)
00152 {
00153     const boost::shared_ptr<AbstractIvpOdeSolver> p_solver = t->GetSolver();
00154     const boost::shared_ptr<AbstractStimulusFunction> p_stimulus = t->GetStimulusFunction();
00155     ar << p_solver;
00156     ar << p_stimulus;
00157 }
00158 
00165 template<class Archive>
00166 inline void load_construct_data(
00167     Archive & ar, LuoRudyIModel1991OdeSystem * t, const unsigned int file_version)
00168 {
00169 
00170     boost::shared_ptr<AbstractIvpOdeSolver> p_solver;
00171     boost::shared_ptr<AbstractStimulusFunction> p_stimulus;
00172     ar >> p_solver;
00173     ar >> p_stimulus;
00174     ::new(t)LuoRudyIModel1991OdeSystem(p_solver, p_stimulus);
00175 }
00176 }
00177 } // namespace ...
00178 
00179 #endif // _LUORUDYIMODEL1991ODESYSTEM_HPP_

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