00001 /* 00002 00003 Copyright (C) University of Oxford, 2005-2010 00004 00005 University of Oxford means the Chancellor, Masters and Scholars of the 00006 University of Oxford, having an administrative office at Wellington 00007 Square, Oxford OX1 2JD, UK. 00008 00009 This file is part of Chaste. 00010 00011 Chaste is free software: you can redistribute it and/or modify it 00012 under the terms of the GNU Lesser General Public License as published 00013 by the Free Software Foundation, either version 2.1 of the License, or 00014 (at your option) any later version. 00015 00016 Chaste is distributed in the hope that it will be useful, but WITHOUT 00017 ANY WARRANTY; without even the implied warranty of MERCHANTABILITY or 00018 FITNESS FOR A PARTICULAR PURPOSE. See the GNU Lesser General Public 00019 License for more details. The offer of Chaste under the terms of the 00020 License is subject to the License being interpreted in accordance with 00021 English Law and subject to any action against the University of Oxford 00022 being under the jurisdiction of the English Courts. 00023 00024 You should have received a copy of the GNU Lesser General Public License 00025 along with Chaste. If not, see <http://www.gnu.org/licenses/>. 00026 00027 */ 00028 #ifndef _LUORUDYIMODEL1991ODESYSTEM_HPP_ 00029 #define _LUORUDYIMODEL1991ODESYSTEM_HPP_ 00030 00031 #include "ChasteSerialization.hpp" 00032 #include <boost/serialization/base_object.hpp> 00033 00034 #include "AbstractCardiacCell.hpp" 00035 #include "AbstractStimulusFunction.hpp" 00036 #include <vector> 00037 00041 class LuoRudyIModel1991OdeSystem : public AbstractCardiacCell 00042 { 00043 private: 00045 friend class boost::serialization::access; 00052 template<class Archive> 00053 void serialize(Archive & archive, const unsigned int version) 00054 { 00055 archive & boost::serialization::base_object<AbstractCardiacCell>(*this); 00056 } 00057 00061 static const double membrane_C; 00063 static const double membrane_F; 00065 static const double membrane_R; 00067 static const double membrane_T; 00069 static const double background_current_E_b; 00071 static const double background_current_g_b; 00073 static const double fast_sodium_current_g_Na; 00075 static const double ionic_concentrations_Ki; 00077 static const double ionic_concentrations_Ko; 00079 static const double ionic_concentrations_Nai; 00081 static const double ionic_concentrations_Nao; 00083 static const double plateau_potassium_current_g_Kp; 00085 static const double time_dependent_potassium_current_PR_NaK; 00086 00088 double fast_sodium_current_E_Na; 00089 00095 void VerifyStateVariables(); 00096 00097 public: 00104 LuoRudyIModel1991OdeSystem(boost::shared_ptr<AbstractIvpOdeSolver> pSolver, 00105 boost::shared_ptr<AbstractStimulusFunction> pIntracellularStimulus); 00106 00110 ~LuoRudyIModel1991OdeSystem(); 00111 00121 void EvaluateYDerivatives(double time, const std::vector<double> &rY, std::vector<double> &rDY); 00122 00128 double GetIIonic(); 00129 00135 double GetIntracellularCalciumConcentration(); 00136 }; 00137 00138 #include "SerializationExportWrapper.hpp" 00139 CHASTE_CLASS_EXPORT(LuoRudyIModel1991OdeSystem); 00140 00141 namespace boost 00142 { 00143 namespace serialization 00144 { 00149 template<class Archive> 00150 inline void save_construct_data( 00151 Archive & ar, const LuoRudyIModel1991OdeSystem * t, const unsigned int file_version) 00152 { 00153 const boost::shared_ptr<AbstractIvpOdeSolver> p_solver = t->GetSolver(); 00154 const boost::shared_ptr<AbstractStimulusFunction> p_stimulus = t->GetStimulusFunction(); 00155 ar << p_solver; 00156 ar << p_stimulus; 00157 } 00158 00165 template<class Archive> 00166 inline void load_construct_data( 00167 Archive & ar, LuoRudyIModel1991OdeSystem * t, const unsigned int file_version) 00168 { 00169 00170 boost::shared_ptr<AbstractIvpOdeSolver> p_solver; 00171 boost::shared_ptr<AbstractStimulusFunction> p_stimulus; 00172 ar >> p_solver; 00173 ar >> p_stimulus; 00174 ::new(t)LuoRudyIModel1991OdeSystem(p_solver, p_stimulus); 00175 } 00176 } 00177 } // namespace ... 00178 00179 #endif // _LUORUDYIMODEL1991ODESYSTEM_HPP_