LuoRudyIModel1991OdeSystem Class Reference

#include <LuoRudyIModel1991OdeSystem.hpp>

Collaboration diagram for LuoRudyIModel1991OdeSystem:

Public Member Functions
	LuoRudyIModel1991OdeSystem (boost::shared_ptr< AbstractIvpOdeSolver > pSolver, boost::shared_ptr< AbstractStimulusFunction > pIntracellularStimulus)
	~LuoRudyIModel1991OdeSystem ()
void	EvaluateYDerivatives (double time, const std::vector< double > &rY, std::vector< double > &rDY)
double	GetIIonic ()
double	GetIntracellularCalciumConcentration ()
Private Member Functions
template<class Archive >
void	serialize (Archive &archive, const unsigned int version)
void	VerifyStateVariables ()
Private Attributes
double	fast_sodium_current_E_Na
Static Private Attributes
static const double	membrane_C = 1.0
static const double	membrane_F = 96484.6
static const double	membrane_R = 8314
static const double	membrane_T = 310.0
static const double	background_current_E_b = -59.87
static const double	background_current_g_b = 0.03921
static const double	fast_sodium_current_g_Na = 23.0
static const double	ionic_concentrations_Ki = 145.0
static const double	ionic_concentrations_Ko = 5.4
static const double	ionic_concentrations_Nai = 18.0
static const double	ionic_concentrations_Nao = 140.0
static const double	plateau_potassium_current_g_Kp = 0.0183
static const double	time_dependent_potassium_current_PR_NaK = 0.01833
Friends
class	boost::serialization::access

Detailed Description

This class represents the Luo-Rudy 1991 system of equations.

Definition at line 41 of file LuoRudyIModel1991OdeSystem.hpp.

Constructor & Destructor Documentation

LuoRudyIModel1991OdeSystem::LuoRudyIModel1991OdeSystem	(	boost::shared_ptr< AbstractIvpOdeSolver >	pSolver,
		boost::shared_ptr< AbstractStimulusFunction >	pIntracellularStimulus
	)

Constructor

Parameters:

	pSolver	is a pointer to the ODE solver
	pIntracellularStimulus	is a pointer to the intracellular stimulus

Constructor

Definition at line 57 of file LuoRudyIModel1991OdeSystem.cpp.

References fast_sodium_current_E_Na, AbstractCardiacCell::Init(), ionic_concentrations_Nai, ionic_concentrations_Nao, membrane_F, membrane_R, membrane_T, and AbstractOdeSystem::mpSystemInfo.

LuoRudyIModel1991OdeSystem::~LuoRudyIModel1991OdeSystem ( void )

Destructor

Definition at line 74 of file LuoRudyIModel1991OdeSystem.cpp.

Member Function Documentation

void LuoRudyIModel1991OdeSystem::EvaluateYDerivatives	(	double	time,
		const std::vector< double > &	rY,
		std::vector< double > &	rDY
	)			`[virtual]`

Fill in a vector representing the RHS of the LuoRudy1991 system of Odes at each time step, y' = [y1' ... yn']. Some ODE solver will call this function repeatedly to solve for y = [y1 ... yn].

Parameters:

	time	the current time, in milliseconds
	rY	current values of the state variables
	rDY	to be filled in with derivatives

Fill in a vector representing the RHS of the LuoRudyIModel1991OdeSystem system of Odes at each time step, y' = [y1' ... yn']. Some ODE solver will call this function repeatedly to solve for y = [y1 ... yn].

Parameters:

	time	the current time, in milliseconds
	rY	current values of the state variables
	rDY	to be filled in with derivatives

Implements AbstractOdeSystem.

Definition at line 92 of file LuoRudyIModel1991OdeSystem.cpp.

References background_current_E_b, background_current_g_b, fast_sodium_current_E_Na, fast_sodium_current_g_Na, AbstractCardiacCell::GetStimulus(), ionic_concentrations_Ki, ionic_concentrations_Ko, ionic_concentrations_Nai, ionic_concentrations_Nao, membrane_C, membrane_F, membrane_R, membrane_T, AbstractCardiacCell::mSetVoltageDerivativeToZero, plateau_potassium_current_g_Kp, and time_dependent_potassium_current_PR_NaK.

double LuoRudyIModel1991OdeSystem::GetIIonic ( ) [virtual]

Returns the ionic current

Returns:: the total ionic current

Implements AbstractCardiacCell.

Definition at line 221 of file LuoRudyIModel1991OdeSystem.cpp.

References background_current_E_b, background_current_g_b, fast_sodium_current_E_Na, fast_sodium_current_g_Na, ionic_concentrations_Ki, ionic_concentrations_Ko, ionic_concentrations_Nai, ionic_concentrations_Nao, membrane_F, membrane_R, membrane_T, AbstractOdeSystem::mStateVariables, plateau_potassium_current_g_Kp, and time_dependent_potassium_current_PR_NaK.

double LuoRudyIModel1991OdeSystem::GetIntracellularCalciumConcentration ( ) [virtual]

Get the intracellular calcium concentration

Returns:: the intracellular calcium concentration

Reimplemented from AbstractCardiacCell.

Definition at line 78 of file LuoRudyIModel1991OdeSystem.cpp.

References AbstractOdeSystem::mStateVariables.

template<class Archive >

void LuoRudyIModel1991OdeSystem::serialize	(	Archive &	archive,
		const unsigned int	version
	)			`[inline, private]`

Archive the member variables.

Parameters:

	archive
	version

Reimplemented from AbstractCardiacCell.

Definition at line 53 of file LuoRudyIModel1991OdeSystem.hpp.

void LuoRudyIModel1991OdeSystem::VerifyStateVariables ( ) [private, virtual]

Range-checking on the current values of the state variables. Make sure all gating variables have are within zero and one, and all concentrations are positive

Reimplemented from AbstractCardiacCell.

Definition at line 277 of file LuoRudyIModel1991OdeSystem.cpp.

References AbstractOdeSystem::DumpState(), and AbstractOdeSystem::rGetStateVariables().