00001 /* 00002 00003 Copyright (C) University of Oxford, 2005-2010 00004 00005 University of Oxford means the Chancellor, Masters and Scholars of the 00006 University of Oxford, having an administrative office at Wellington 00007 Square, Oxford OX1 2JD, UK. 00008 00009 This file is part of Chaste. 00010 00011 Chaste is free software: you can redistribute it and/or modify it 00012 under the terms of the GNU Lesser General Public License as published 00013 by the Free Software Foundation, either version 2.1 of the License, or 00014 (at your option) any later version. 00015 00016 Chaste is distributed in the hope that it will be useful, but WITHOUT 00017 ANY WARRANTY; without even the implied warranty of MERCHANTABILITY or 00018 FITNESS FOR A PARTICULAR PURPOSE. See the GNU Lesser General Public 00019 License for more details. The offer of Chaste under the terms of the 00020 License is subject to the License being interpreted in accordance with 00021 English Law and subject to any action against the University of Oxford 00022 being under the jurisdiction of the English Courts. 00023 00024 You should have received a copy of the GNU Lesser General Public License 00025 along with Chaste. If not, see <http://www.gnu.org/licenses/>. 00026 00027 */ 00028 00029 #ifndef ABSTRACTCARDIACCELLINTERFACE_HPP_ 00030 #define ABSTRACTCARDIACCELLINTERFACE_HPP_ 00031 00032 #include <boost/shared_ptr.hpp> 00033 00034 #include "ChasteSerialization.hpp" 00035 #include "ClassIsAbstract.hpp" 00036 00037 #include "AbstractIvpOdeSolver.hpp" 00038 #include "AbstractStimulusFunction.hpp" 00039 #include "OdeSolution.hpp" 00040 00053 class AbstractCardiacCellInterface 00054 { 00055 public: 00068 AbstractCardiacCellInterface(boost::shared_ptr<AbstractIvpOdeSolver> pOdeSolver, 00069 unsigned voltageIndex, 00070 boost::shared_ptr<AbstractStimulusFunction> pIntracellularStimulus); 00071 00073 virtual ~AbstractCardiacCellInterface(); 00074 00078 virtual void ResetToInitialConditions()=0; 00079 00089 virtual OdeSolution Compute(double tStart, double tEnd, double tSamp=0.0)=0; 00090 00099 virtual void ComputeExceptVoltage(double tStart, double tEnd)=0; 00100 00123 virtual double GetIIonic()=0; 00124 00128 virtual void SetVoltage(double voltage)=0; 00129 00134 virtual double GetVoltage()=0; 00135 00137 unsigned GetVoltageIndex(); 00138 00144 void SetStimulusFunction(boost::shared_ptr<AbstractStimulusFunction> pStimulus); 00145 00151 double GetStimulus(double time); 00152 00159 void SetIntracellularStimulusFunction(boost::shared_ptr<AbstractStimulusFunction> pStimulus); 00160 00168 double GetIntracellularStimulus(double time); 00169 00176 double GetIntracellularAreaStimulus(double time); 00177 00186 void SetUsedInTissueSimulation(bool tissue=true); 00187 00194 virtual void UseCellMLDefaultStimulus(); 00195 00199 bool HasCellMLDefaultStimulus(); 00200 00207 virtual void VerifyStateVariables() 00208 { 00209 // See also #794. 00210 } 00211 00215 boost::shared_ptr<AbstractStimulusFunction> GetStimulusFunction(); 00216 00223 const boost::shared_ptr<AbstractStimulusFunction> GetStimulusFunction() const; 00224 00231 const boost::shared_ptr<AbstractIvpOdeSolver> GetSolver() const; 00232 00233 protected: 00235 unsigned mVoltageIndex; 00236 00238 boost::shared_ptr<AbstractIvpOdeSolver> mpOdeSolver; 00239 00241 boost::shared_ptr<AbstractStimulusFunction> mpIntracellularStimulus; 00242 00248 bool mSetVoltageDerivativeToZero; 00249 00251 bool mIsUsedInTissue; 00252 00254 bool mHasDefaultStimulusFromCellML; 00255 00256 private: 00258 friend class boost::serialization::access; 00268 template<class Archive> 00269 void serialize(Archive & archive, const unsigned int version) 00270 { 00271 } 00272 }; 00273 00274 CLASS_IS_ABSTRACT(AbstractCardiacCellInterface) 00275 00276 00277 #endif /*ABSTRACTCARDIACCELLINTERFACE_HPP_*/