Mirams2010WntOdeSystem.hpp

00001 /*
00002 
00003 Copyright (C) University of Oxford, 2005-2010
00004 
00005 University of Oxford means the Chancellor, Masters and Scholars of the
00006 University of Oxford, having an administrative office at Wellington
00007 Square, Oxford OX1 2JD, UK.
00008 
00009 This file is part of Chaste.
00010 
00011 Chaste is free software: you can redistribute it and/or modify it
00012 under the terms of the GNU Lesser General Public License as published
00013 by the Free Software Foundation, either version 2.1 of the License, or
00014 (at your option) any later version.
00015 
00016 Chaste is distributed in the hope that it will be useful, but WITHOUT
00017 ANY WARRANTY; without even the implied warranty of MERCHANTABILITY or
00018 FITNESS FOR A PARTICULAR PURPOSE.  See the GNU Lesser General Public
00019 License for more details. The offer of Chaste under the terms of the
00020 License is subject to the License being interpreted in accordance with
00021 English Law and subject to any action against the University of Oxford
00022 being under the jurisdiction of the English Courts.
00023 
00024 You should have received a copy of the GNU Lesser General Public License
00025 along with Chaste. If not, see <http://www.gnu.org/licenses/>.
00026 
00027 */
00028 #ifndef MIRAMS2010WNTODESYSTEM_HPP_
00029 #define MIRAMS2010WNTODESYSTEM_HPP_
00030 
00031 #include "ChasteSerialization.hpp"
00032 #include <boost/serialization/base_object.hpp>
00033 #include <boost/serialization/shared_ptr.hpp>
00034 
00035 #include <cmath>
00036 #include <iostream>
00037 
00038 #include "AbstractOdeSystem.hpp"
00039 #include "AbstractCellMutationState.hpp"
00040 
00041 // Needed here to avoid serialization errors
00042 #include "ApcOneHitCellMutationState.hpp"
00043 #include "ApcTwoHitCellMutationState.hpp"
00044 #include "BetaCateninOneHitCellMutationState.hpp"
00045 #include "CellLabel.hpp"
00046 #include "WildTypeCellMutationState.hpp"
00047 
00059 class Mirams2010WntOdeSystem : public AbstractOdeSystem
00060 {
00061 private:
00062 
00068     double mA;
00070     double mB;
00072     double mC;
00074     double mD;
00076     double mE;
00078     double mF;
00079 
00081     boost::shared_ptr<AbstractCellMutationState> mpMutationState;
00082 
00084     double mWntLevel;
00085 
00086     friend class boost::serialization::access;
00093     template<class Archive>
00094     void serialize(Archive & archive, const unsigned int version)
00095     {
00096         archive & boost::serialization::base_object<AbstractOdeSystem>(*this);
00097     }
00098 
00099 public:
00100 
00108     Mirams2010WntOdeSystem(double wntLevel=0.0,
00109                            boost::shared_ptr<AbstractCellMutationState> pMutationState=boost::shared_ptr<AbstractCellMutationState>(),
00110                            std::vector<double> stateVariables=std::vector<double>());
00111 
00115     ~Mirams2010WntOdeSystem();
00116 
00120     void Init();
00121 
00130     void SetMutationState(boost::shared_ptr<AbstractCellMutationState> pMutationState);
00131 
00137     const boost::shared_ptr<AbstractCellMutationState> GetMutationState() const;
00138 
00149     void EvaluateYDerivatives(double time, const std::vector<double>& rY, std::vector<double>& rDY);
00150 
00154     double GetWntLevel() const;
00155 };
00156 
00157 // Declare identifier for the serializer
00158 #include "SerializationExportWrapper.hpp"
00159 CHASTE_CLASS_EXPORT(Mirams2010WntOdeSystem)
00160 
00161 namespace boost
00162 {
00163 namespace serialization
00164 {
00168 template<class Archive>
00169 inline void save_construct_data(
00170     Archive & ar, const Mirams2010WntOdeSystem * t, const BOOST_PFTO unsigned int file_version)
00171 {
00172     // Save data required to construct instance
00173     const double wnt_level = t->GetWntLevel();
00174     ar & wnt_level;
00175 
00176     const boost::shared_ptr<AbstractCellMutationState> p_mutation_state = t->GetMutationState();
00177     ar & p_mutation_state;
00178 
00179     const std::vector<double> state_variables = t->rGetConstStateVariables();
00180     ar & state_variables;
00181 }
00182 
00186 template<class Archive>
00187 inline void load_construct_data(
00188     Archive & ar, Mirams2010WntOdeSystem * t, const unsigned int file_version)
00189 {
00190     // Retrieve data from archive required to construct new instance
00191     double wnt_level;
00192     ar & wnt_level;
00193 
00194     boost::shared_ptr<AbstractCellMutationState> p_mutation_state;
00195     ar & p_mutation_state;
00196 
00197     std::vector<double> state_variables;
00198     ar & state_variables;
00199 
00200     // Invoke inplace constructor to initialise instance
00201     ::new(t)Mirams2010WntOdeSystem(wnt_level, p_mutation_state, state_variables);
00202 }
00203 }
00204 } // namespace ...
00205 
00206 #endif /*MIRAMS2010WNTODESYSTEM_HPP_*/

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