00001 /* 00002 00003 Copyright (C) University of Oxford, 2005-2010 00004 00005 University of Oxford means the Chancellor, Masters and Scholars of the 00006 University of Oxford, having an administrative office at Wellington 00007 Square, Oxford OX1 2JD, UK. 00008 00009 This file is part of Chaste. 00010 00011 Chaste is free software: you can redistribute it and/or modify it 00012 under the terms of the GNU Lesser General Public License as published 00013 by the Free Software Foundation, either version 2.1 of the License, or 00014 (at your option) any later version. 00015 00016 Chaste is distributed in the hope that it will be useful, but WITHOUT 00017 ANY WARRANTY; without even the implied warranty of MERCHANTABILITY or 00018 FITNESS FOR A PARTICULAR PURPOSE. See the GNU Lesser General Public 00019 License for more details. The offer of Chaste under the terms of the 00020 License is subject to the License being interpreted in accordance with 00021 English Law and subject to any action against the University of Oxford 00022 being under the jurisdiction of the English Courts. 00023 00024 You should have received a copy of the GNU Lesser General Public License 00025 along with Chaste. If not, see <http://www.gnu.org/licenses/>. 00026 00027 */ 00028 00029 #ifndef SIMPLEOXYGENBASEDCELLCYCLEMODEL_HPP_ 00030 #define SIMPLEOXYGENBASEDCELLCYCLEMODEL_HPP_ 00031 00032 #include "AbstractSimpleCellCycleModel.hpp" 00033 #include "CellwiseData.hpp" 00034 00045 class SimpleOxygenBasedCellCycleModel : public AbstractSimpleCellCycleModel 00046 { 00047 private: 00048 00049 friend class boost::serialization::access; 00050 template<class Archive> 00051 void serialize(Archive & archive, const unsigned int version) 00052 { 00053 archive & boost::serialization::base_object<AbstractSimpleCellCycleModel>(*this); 00054 archive & mTimeSpentInG1Phase; 00055 archive & mCurrentHypoxicDuration; 00056 archive & mCurrentHypoxiaOnsetTime; 00057 archive & mHypoxicConcentration; 00058 archive & mQuiescentConcentration; 00059 archive & mCriticalHypoxicDuration; 00060 } 00061 00062 protected: 00063 00068 double mTimeSpentInG1Phase; 00069 00074 double mCurrentHypoxicDuration; 00075 00079 double mCurrentHypoxiaOnsetTime; 00080 00086 double mHypoxicConcentration; 00087 00093 double mQuiescentConcentration; 00094 00099 double mCriticalHypoxicDuration; 00100 00101 public: 00102 00106 SimpleOxygenBasedCellCycleModel(); 00107 00111 void UpdateCellCyclePhase(); 00112 00117 void UpdateHypoxicDuration(); 00118 00122 double GetCurrentHypoxicDuration(); 00123 00127 double GetCurrentHypoxiaOnsetTime(); 00128 00133 AbstractCellCycleModel* CreateCellCycleModel(); 00134 00138 double GetHypoxicConcentration(); 00139 00145 void SetHypoxicConcentration(double hypoxicConcentration); 00146 00150 double GetQuiescentConcentration(); 00151 00157 void SetQuiescentConcentration(double quiescentConcentration); 00158 00162 double GetCriticalHypoxicDuration(); 00163 00169 void SetCriticalHypoxicDuration(double criticalHypoxicDuration); 00170 00176 void SetCurrentHypoxiaOnsetTime(double currentHypoxiaOnsetTime); 00177 }; 00178 00179 // Declare identifier for the serializer 00180 #include "SerializationExportWrapper.hpp" 00181 CHASTE_CLASS_EXPORT(SimpleOxygenBasedCellCycleModel) 00182 00183 #endif /*SIMPLEOXYGENBASEDCELLCYCLEMODEL_HPP_*/