UniformG1GenerationalCellCycleModel.cpp

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*/

#include "UniformG1GenerationalCellCycleModel.hpp"
#include "StemCellProliferativeType.hpp"
#include "TransitCellProliferativeType.hpp"
#include "DifferentiatedCellProliferativeType.hpp"

UniformG1GenerationalCellCycleModel::UniformG1GenerationalCellCycleModel()
{
}

UniformG1GenerationalCellCycleModel::UniformG1GenerationalCellCycleModel(const UniformG1GenerationalCellCycleModel& rModel)
   : AbstractSimpleGenerationalCellCycleModel(rModel)
{
    /*
     * The member variables mGeneration and mMaxTransitGeneration are
     * initialized in the AbstractSimpleGenerationalCellCycleModel
     * constructor.
     *
     * The member variables mCurrentCellCyclePhase, mG1Duration,
     * mMinimumGapDuration, mStemCellG1Duration, mTransitCellG1Duration,
     * mSDuration, mG2Duration and mMDuration are initialized in the
     * AbstractPhaseBasedCellCycleModel constructor.
     *
     * The member variables mBirthTime, mReadyToDivide and mDimension
     * are initialized in the AbstractCellCycleModel constructor.
     *
     * Note that mG1Duration is (re)set as soon as InitialiseDaughterCell()
     * is called on the new cell-cycle model.
     */
}

AbstractCellCycleModel* UniformG1GenerationalCellCycleModel::CreateCellCycleModel()
{
    return new UniformG1GenerationalCellCycleModel(*this);
}

void UniformG1GenerationalCellCycleModel::SetG1Duration()
{
    RandomNumberGenerator* p_gen = RandomNumberGenerator::Instance();

    assert(mpCell != nullptr);

    if (mpCell->GetCellProliferativeType()->IsType<StemCellProliferativeType>())
    {
        mG1Duration = GetStemCellG1Duration() + 4*p_gen->ranf(); // U[14,18] for default parameters (mStemCellG1Duration) according to Meineke
    }
    else if (mpCell->GetCellProliferativeType()->IsType<TransitCellProliferativeType>())
    {
        mG1Duration = GetTransitCellG1Duration() + 2*p_gen->ranf(); // U[4,6] for default parameters (mTransitG1CellDuration) according to Meineke
    }
    else if (mpCell->GetCellProliferativeType()->IsType<DifferentiatedCellProliferativeType>())
    {
        mG1Duration = DBL_MAX;
    }
    else
    {
        NEVER_REACHED;
    }
}

void UniformG1GenerationalCellCycleModel::OutputCellCycleModelParameters(out_stream& rParamsFile)
{
    // No new parameters to output, so just call method on direct parent class
    AbstractSimpleGenerationalCellCycleModel::OutputCellCycleModelParameters(rParamsFile);
}

// Serialization for Boost >= 1.36
#include "SerializationExportWrapperForCpp.hpp"
CHASTE_CLASS_EXPORT(UniformG1GenerationalCellCycleModel)