#include <CryptShovingCaBasedDivisionRule.hpp>

Inheritance diagram for CryptShovingCaBasedDivisionRule:

Collaboration diagram for CryptShovingCaBasedDivisionRule:

Public Member Functions
	CryptShovingCaBasedDivisionRule ()

virtual	~CryptShovingCaBasedDivisionRule ()

bool	IsNodeOnBase (unsigned NodeIndex, PottsMesh< 2 > *pPottsMesh)

virtual bool	IsRoomToDivide (CellPtr pParentCell, CaBasedCellPopulation< 2 > &rCellPopulation)

virtual unsigned	CalculateDaughterNodeIndex (CellPtr pNewCell, CellPtr pParentCell, CaBasedCellPopulation< 2 > &rCellPopulation)

Public Member Functions inherited from AbstractCaBasedDivisionRule< 2 >
	AbstractCaBasedDivisionRule ()

virtual	~AbstractCaBasedDivisionRule ()

virtual bool	IsRoomToDivide (CellPtr pParentCell, CaBasedCellPopulation< SPACE_DIM > &rCellPopulation)=0

virtual unsigned	CalculateDaughterNodeIndex (CellPtr pNewCell, CellPtr pParentCell, CaBasedCellPopulation< SPACE_DIM > &rCellPopulation)=0

void	OutputCellCaBasedDivisionRuleInfo (out_stream &rParamsFile)

Public Member Functions inherited from Identifiable
virtual	~Identifiable ()

std::string	GetIdentifier () const

Private Member Functions
template<class Archive >
void	serialize (Archive &archive, const unsigned int version)

Friends
class	boost::serialization::access

Additional Inherited Members
Protected Member Functions inherited from AbstractCaBasedDivisionRule< 2 >
virtual void	OutputCellCaBasedDivisionRuleParameters (out_stream &rParamsFile)

Detailed Description

A division rule for CA-based cell populations to say how cells divide. Here they can divide in a 'north-east' or 'west' direction, as in model 3 of the following paper:

Loeffler et al (1986). Intestinal cell proliferation. I. A comprehensive model of steady‐state proliferation in the crypt. Cell Proliferation 19(6):627-645.

Definition at line 57 of file CryptShovingCaBasedDivisionRule.hpp.

Constructor & Destructor Documentation

CryptShovingCaBasedDivisionRule::CryptShovingCaBasedDivisionRule ( )

inline

Default constructor.

Definition at line 79 of file CryptShovingCaBasedDivisionRule.hpp.

virtual CryptShovingCaBasedDivisionRule::~CryptShovingCaBasedDivisionRule ( )

inlinevirtual

Empty destructor.

Definition at line 84 of file CryptShovingCaBasedDivisionRule.hpp.

Member Function Documentation

unsigned CryptShovingCaBasedDivisionRule::CalculateDaughterNodeIndex	(	CellPtr	pNewCell,
		CellPtr	pParentCell,
		CaBasedCellPopulation< 2 > &	rCellPopulation
	)

virtual

Return the index for the Daughter node. This method can be used to move cells out of the way as necessary.

Here cells divide East North or west and move the occupying cells North.

Parameters

pNewCell	The cell to new cell
pParentCell	The parent cell
rCellPopulation	The CA-based cell population

Returns: the node index for the daughter cell.

Definition at line 74 of file CryptShovingCaBasedDivisionRule.cpp.

References AbstractCellPopulation< DIM >::GetCellUsingLocationIndex(), AbstractCellPopulation< DIM >::GetLocationIndexUsingCell(), PottsMesh< DIM >::GetVonNeumannNeighbouringNodeIndices(), RandomNumberGenerator::Instance(), IsNodeOnBase(), CaBasedCellPopulation< DIM >::IsSiteAvailable(), AbstractCellPopulation< DIM >::MoveCellInLocationMap(), RandomNumberGenerator::randMod(), and CaBasedCellPopulation< DIM >::rGetMesh().

bool CryptShovingCaBasedDivisionRule::IsNodeOnBase	(	unsigned	NodeIndex,
		PottsMesh< 2 > *	pPottsMesh
	)

Helper method to see if cells are on the base of the crypt or not Also throws exception if cells reach the top boundary of the crypt.

Parameters

NodeIndex	The node of interest
pPottsMesh	The mesh containing the nodes

Returns: if the site is available.

Definition at line 40 of file CryptShovingCaBasedDivisionRule.cpp.

References EXCEPTION, PottsMesh< DIM >::GetVonNeumannNeighbouringNodeIndices(), and NEVER_REACHED.

Referenced by CalculateDaughterNodeIndex().

bool CryptShovingCaBasedDivisionRule::IsRoomToDivide	(	CellPtr	pParentCell,
		CaBasedCellPopulation< 2 > &	rCellPopulation
	)

virtual

Return whether there is room to divide at all.

Parameters

pParentCell	The cell to divide
rCellPopulation	The CA-based cell population

Returns: if the site is available.

Definition at line 69 of file CryptShovingCaBasedDivisionRule.cpp.

template<class Archive >

void CryptShovingCaBasedDivisionRule::serialize	(	Archive &	archive,
		const unsigned int	version
	)

inlineprivate

Serialize the object and its member variables.

Parameters

archive	the archive
version	the current version of this class

Definition at line 69 of file CryptShovingCaBasedDivisionRule.hpp.

The documentation for this class was generated from the following files:

crypt/src/division_rules/CryptShovingCaBasedDivisionRule.hpp
crypt/src/division_rules/CryptShovingCaBasedDivisionRule.cpp

Public Member Functions

Private Member Functions

Friends

Additional Inherited Members

Detailed Description

Constructor & Destructor Documentation

Member Function Documentation