00001 /* 00002 00003 Copyright (C) University of Oxford, 2005-2011 00004 00005 University of Oxford means the Chancellor, Masters and Scholars of the 00006 University of Oxford, having an administrative office at Wellington 00007 Square, Oxford OX1 2JD, UK. 00008 00009 This file is part of Chaste. 00010 00011 Chaste is free software: you can redistribute it and/or modify it 00012 under the terms of the GNU Lesser General Public License as published 00013 by the Free Software Foundation, either version 2.1 of the License, or 00014 (at your option) any later version. 00015 00016 Chaste is distributed in the hope that it will be useful, but WITHOUT 00017 ANY WARRANTY; without even the implied warranty of MERCHANTABILITY or 00018 FITNESS FOR A PARTICULAR PURPOSE. See the GNU Lesser General Public 00019 License for more details. The offer of Chaste under the terms of the 00020 License is subject to the License being interpreted in accordance with 00021 English Law and subject to any action against the University of Oxford 00022 being under the jurisdiction of the English Courts. 00023 00024 You should have received a copy of the GNU Lesser General Public License 00025 along with Chaste. If not, see <http://www.gnu.org/licenses/>. 00026 00027 */ 00028 00029 #include "HeartConfig.hpp" // First for Boost 1.33/PETSc 2.2 00030 00031 #include "AbstractCardiacCellInterface.hpp" 00032 00033 #include "Exception.hpp" 00034 00035 00036 AbstractCardiacCellInterface::AbstractCardiacCellInterface( 00037 boost::shared_ptr<AbstractIvpOdeSolver> pOdeSolver, 00038 unsigned voltageIndex, 00039 boost::shared_ptr<AbstractStimulusFunction> pIntracellularStimulus) 00040 : mVoltageIndex(voltageIndex), 00041 mpOdeSolver(pOdeSolver), 00042 mpIntracellularStimulus(pIntracellularStimulus), 00043 mSetVoltageDerivativeToZero(false), 00044 mIsUsedInTissue(false), 00045 mHasDefaultStimulusFromCellML(false) 00046 { 00047 } 00048 00049 00050 AbstractCardiacCellInterface::~AbstractCardiacCellInterface() 00051 { 00052 } 00053 00054 00055 unsigned AbstractCardiacCellInterface::GetVoltageIndex() 00056 { 00057 return mVoltageIndex; 00058 } 00059 00060 00061 void AbstractCardiacCellInterface::SetStimulusFunction(boost::shared_ptr<AbstractStimulusFunction> pStimulus) 00062 { 00063 SetIntracellularStimulusFunction(pStimulus); 00064 } 00065 00066 00067 double AbstractCardiacCellInterface::GetStimulus(double time) 00068 { 00069 return GetIntracellularStimulus(time); 00070 } 00071 00072 00073 void AbstractCardiacCellInterface::SetIntracellularStimulusFunction(boost::shared_ptr<AbstractStimulusFunction> pStimulus) 00074 { 00075 mpIntracellularStimulus = pStimulus; 00076 } 00077 00078 00079 double AbstractCardiacCellInterface::GetIntracellularStimulus(double time) 00080 { 00081 return mpIntracellularStimulus->GetStimulus(time); 00082 } 00083 00084 00085 double AbstractCardiacCellInterface::GetIntracellularAreaStimulus(double time) 00086 { 00087 double stim; 00088 if (mIsUsedInTissue) 00089 { 00090 // Convert from uA/cm^3 to uA/cm^2 by dividing by Am 00091 stim = GetIntracellularStimulus(time) / HeartConfig::Instance()->GetSurfaceAreaToVolumeRatio(); 00092 } 00093 else 00094 { 00095 stim = GetIntracellularStimulus(time); 00096 } 00097 return stim; 00098 } 00099 00100 void AbstractCardiacCellInterface::SetUsedInTissueSimulation(bool tissue) 00101 { 00102 mIsUsedInTissue = tissue; 00103 } 00104 00105 void AbstractCardiacCellInterface::UseCellMLDefaultStimulus() 00106 { 00107 assert(!mHasDefaultStimulusFromCellML); 00108 EXCEPTION("This class has no default stimulus from CellML metadata."); 00109 } 00110 00111 bool AbstractCardiacCellInterface::HasCellMLDefaultStimulus() 00112 { 00113 return mHasDefaultStimulusFromCellML; 00114 } 00115 00116 boost::shared_ptr<AbstractStimulusFunction> AbstractCardiacCellInterface::GetStimulusFunction() 00117 { 00118 return mpIntracellularStimulus; 00119 } 00120 00121 // Methods needed by boost serialization. 00122 const boost::shared_ptr<AbstractStimulusFunction> AbstractCardiacCellInterface::GetStimulusFunction() const 00123 { 00124 return mpIntracellularStimulus; 00125 } 00126 00127 const boost::shared_ptr<AbstractIvpOdeSolver> AbstractCardiacCellInterface::GetSolver() const 00128 { 00129 return mpOdeSolver; 00130 } 00131 00132 void AbstractCardiacCellInterface::SetVoltageDerivativeToZero(bool clamp) 00133 { 00134 mSetVoltageDerivativeToZero = clamp; 00135 } 00136 00137