Mirams2010WntOdeSystem.hpp

00001 /*
00002 
00003 Copyright (C) University of Oxford, 2005-2011
00004 
00005 University of Oxford means the Chancellor, Masters and Scholars of the
00006 University of Oxford, having an administrative office at Wellington
00007 Square, Oxford OX1 2JD, UK.
00008 
00009 This file is part of Chaste.
00010 
00011 Chaste is free software: you can redistribute it and/or modify it
00012 under the terms of the GNU Lesser General Public License as published
00013 by the Free Software Foundation, either version 2.1 of the License, or
00014 (at your option) any later version.
00015 
00016 Chaste is distributed in the hope that it will be useful, but WITHOUT
00017 ANY WARRANTY; without even the implied warranty of MERCHANTABILITY or
00018 FITNESS FOR A PARTICULAR PURPOSE.  See the GNU Lesser General Public
00019 License for more details. The offer of Chaste under the terms of the
00020 License is subject to the License being interpreted in accordance with
00021 English Law and subject to any action against the University of Oxford
00022 being under the jurisdiction of the English Courts.
00023 
00024 You should have received a copy of the GNU Lesser General Public License
00025 along with Chaste. If not, see <http://www.gnu.org/licenses/>.
00026 
00027 */
00028 
00029 #ifndef MIRAMS2010WNTODESYSTEM_HPP_
00030 #define MIRAMS2010WNTODESYSTEM_HPP_
00031 
00032 #include "ChasteSerialization.hpp"
00033 #include <boost/serialization/base_object.hpp>
00034 #include <boost/serialization/shared_ptr.hpp>
00035 
00036 #include <cmath>
00037 #include <iostream>
00038 
00039 #include "AbstractOdeSystem.hpp"
00040 #include "AbstractCellMutationState.hpp"
00041 
00042 // Needed here to avoid serialization errors
00043 #include "ApcOneHitCellMutationState.hpp"
00044 #include "ApcTwoHitCellMutationState.hpp"
00045 #include "BetaCateninOneHitCellMutationState.hpp"
00046 #include "CellLabel.hpp"
00047 #include "WildTypeCellMutationState.hpp"
00048 
00060 class Mirams2010WntOdeSystem : public AbstractOdeSystem
00061 {
00062 private:
00063 
00069     double mA;
00071     double mB;
00073     double mC;
00075     double mD;
00077     double mE;
00079     double mF;
00080 
00082     boost::shared_ptr<AbstractCellMutationState> mpMutationState;
00083 
00085     double mWntLevel;
00086 
00087     friend class boost::serialization::access;
00094     template<class Archive>
00095     void serialize(Archive & archive, const unsigned int version)
00096     {
00097         archive & boost::serialization::base_object<AbstractOdeSystem>(*this);
00098     }
00099 
00100 public:
00101 
00109     Mirams2010WntOdeSystem(double wntLevel=0.0,
00110                            boost::shared_ptr<AbstractCellMutationState> pMutationState=boost::shared_ptr<AbstractCellMutationState>(),
00111                            std::vector<double> stateVariables=std::vector<double>());
00112 
00116     ~Mirams2010WntOdeSystem();
00117 
00121     void Init();
00122 
00131     void SetMutationState(boost::shared_ptr<AbstractCellMutationState> pMutationState);
00132 
00138     const boost::shared_ptr<AbstractCellMutationState> GetMutationState() const;
00139 
00150     void EvaluateYDerivatives(double time, const std::vector<double>& rY, std::vector<double>& rDY);
00151 
00155     double GetWntLevel() const;
00156 };
00157 
00158 // Declare identifier for the serializer
00159 #include "SerializationExportWrapper.hpp"
00160 CHASTE_CLASS_EXPORT(Mirams2010WntOdeSystem)
00161 
00162 namespace boost
00163 {
00164 namespace serialization
00165 {
00169 template<class Archive>
00170 inline void save_construct_data(
00171     Archive & ar, const Mirams2010WntOdeSystem * t, const BOOST_PFTO unsigned int file_version)
00172 {
00173     // Save data required to construct instance
00174     const double wnt_level = t->GetWntLevel();
00175     ar & wnt_level;
00176 
00177     const boost::shared_ptr<AbstractCellMutationState> p_mutation_state = t->GetMutationState();
00178     ar & p_mutation_state;
00179 
00180     const std::vector<double> state_variables = t->rGetConstStateVariables();
00181     ar & state_variables;
00182 }
00183 
00187 template<class Archive>
00188 inline void load_construct_data(
00189     Archive & ar, Mirams2010WntOdeSystem * t, const unsigned int file_version)
00190 {
00191     // Retrieve data from archive required to construct new instance
00192     double wnt_level;
00193     ar & wnt_level;
00194 
00195     boost::shared_ptr<AbstractCellMutationState> p_mutation_state;
00196     ar & p_mutation_state;
00197 
00198     std::vector<double> state_variables;
00199     ar & state_variables;
00200 
00201     // Invoke inplace constructor to initialise instance
00202     ::new(t)Mirams2010WntOdeSystem(wnt_level, p_mutation_state, state_variables);
00203 }
00204 }
00205 } // namespace ...
00206 
00207 #endif /*MIRAMS2010WNTODESYSTEM_HPP_*/
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