00001 /* 00002 00003 Copyright (C) University of Oxford, 2005-2011 00004 00005 University of Oxford means the Chancellor, Masters and Scholars of the 00006 University of Oxford, having an administrative office at Wellington 00007 Square, Oxford OX1 2JD, UK. 00008 00009 This file is part of Chaste. 00010 00011 Chaste is free software: you can redistribute it and/or modify it 00012 under the terms of the GNU Lesser General Public License as published 00013 by the Free Software Foundation, either version 2.1 of the License, or 00014 (at your option) any later version. 00015 00016 Chaste is distributed in the hope that it will be useful, but WITHOUT 00017 ANY WARRANTY; without even the implied warranty of MERCHANTABILITY or 00018 FITNESS FOR A PARTICULAR PURPOSE. See the GNU Lesser General Public 00019 License for more details. The offer of Chaste under the terms of the 00020 License is subject to the License being interpreted in accordance with 00021 English Law and subject to any action against the University of Oxford 00022 being under the jurisdiction of the English Courts. 00023 00024 You should have received a copy of the GNU Lesser General Public License 00025 along with Chaste. If not, see <http://www.gnu.org/licenses/>. 00026 00027 */ 00028 00029 #ifndef TYSONNOVAKCELLCYCLEMODEL_HPP_ 00030 #define TYSONNOVAKCELLCYCLEMODEL_HPP_ 00031 00032 #include "ChasteSerialization.hpp" 00033 #include <boost/serialization/base_object.hpp> 00034 00035 #include "AbstractOdeBasedCellCycleModel.hpp" 00036 #include "TysonNovak2001OdeSystem.hpp" 00037 00038 00048 class TysonNovakCellCycleModel : public AbstractOdeBasedCellCycleModel 00049 { 00050 private: 00051 00052 friend class TestOdeBasedCellCycleModels; 00053 00055 friend class boost::serialization::access; 00062 template<class Archive> 00063 void serialize(Archive & archive, const unsigned int version) 00064 { 00065 archive & boost::serialization::base_object<AbstractOdeBasedCellCycleModel>(*this); 00066 } 00067 00068 public: 00069 00075 TysonNovakCellCycleModel(boost::shared_ptr<AbstractCellCycleModelOdeSolver> pOdeSolver = boost::shared_ptr<AbstractCellCycleModelOdeSolver>()); 00076 00088 void Initialise(); 00089 00094 void ResetForDivision(); 00095 00100 AbstractCellCycleModel* CreateCellCycleModel(); 00101 00105 double GetSDuration(); 00106 00110 double GetG2Duration(); 00111 00115 double GetMDuration(); 00116 00120 void InitialiseDaughterCell(); 00121 00125 double GetAverageTransitCellCycleTime(); 00126 00130 double GetAverageStemCellCycleTime(); 00131 00135 bool CanCellTerminallyDifferentiate(); 00136 00142 virtual void OutputCellCycleModelParameters(out_stream& rParamsFile); 00143 }; 00144 00145 // Declare identifier for the serializer 00146 #include "SerializationExportWrapper.hpp" 00147 CHASTE_CLASS_EXPORT(TysonNovakCellCycleModel) 00148 #include "CellCycleModelOdeSolverExportWrapper.hpp" 00149 EXPORT_CELL_CYCLE_MODEL_ODE_SOLVER(TysonNovakCellCycleModel) 00150 00151 #endif /*TYSONNOVAKCELLCYCLEMODEL_HPP_*/