Chaste Release::3.1
AbstractSimpleCellCycleModel.cpp
00001 /*
00002 
00003 Copyright (c) 2005-2012, University of Oxford.
00004 All rights reserved.
00005 
00006 University of Oxford means the Chancellor, Masters and Scholars of the
00007 University of Oxford, having an administrative office at Wellington
00008 Square, Oxford OX1 2JD, UK.
00009 
00010 This file is part of Chaste.
00011 
00012 Redistribution and use in source and binary forms, with or without
00013 modification, are permitted provided that the following conditions are met:
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00015    this list of conditions and the following disclaimer.
00016  * Redistributions in binary form must reproduce the above copyright notice,
00017    this list of conditions and the following disclaimer in the documentation
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00022 
00023 THIS SOFTWARE IS PROVIDED BY THE COPYRIGHT HOLDERS AND CONTRIBUTORS "AS IS"
00024 AND ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE
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00026 ARE DISCLAIMED. IN NO EVENT SHALL THE COPYRIGHT HOLDER OR CONTRIBUTORS BE
00027 LIABLE FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR
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00029 GOODS OR SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS INTERRUPTION)
00030 HOWEVER CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT
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00033 
00034 */
00035 
00036 #include "AbstractSimpleCellCycleModel.hpp"
00037 #include "Exception.hpp"
00038 
00039 AbstractSimpleCellCycleModel::AbstractSimpleCellCycleModel()
00040 {
00041 }
00042 
00043 AbstractSimpleCellCycleModel::~AbstractSimpleCellCycleModel()
00044 {
00045 }
00046 
00047 void AbstractSimpleCellCycleModel::Initialise()
00048 {
00049     SetG1Duration();
00050 }
00051 
00052 void AbstractSimpleCellCycleModel::InitialiseDaughterCell()
00053 {
00054     AbstractCellCycleModel::InitialiseDaughterCell();
00055     SetG1Duration();
00056 }
00057 
00058 void AbstractSimpleCellCycleModel::SetG1Duration()
00059 {
00060     assert(mpCell != NULL);
00061 
00062     switch (mpCell->GetCellProliferativeType())
00063     {
00064         case STEM:
00065             mG1Duration = GetStemCellG1Duration();
00066             break;
00067         case TRANSIT:
00068             mG1Duration = GetTransitCellG1Duration();
00069             break;
00070         case DIFFERENTIATED:
00071             mG1Duration = DBL_MAX;
00072             break;
00073         default:
00074             NEVER_REACHED;
00075     }
00076 }
00077 
00078 void AbstractSimpleCellCycleModel::ResetForDivision()
00079 {
00080     AbstractCellCycleModel::ResetForDivision();
00081     mBirthTime = SimulationTime::Instance()->GetTime();
00082     SetG1Duration();
00083 }
00084 
00085 void AbstractSimpleCellCycleModel::UpdateCellCyclePhase()
00086 {
00087     double time_since_birth = GetAge();
00088     assert(time_since_birth >= 0);
00089 
00090     if (mpCell->GetCellProliferativeType() == DIFFERENTIATED)
00091     {
00092         mCurrentCellCyclePhase = G_ZERO_PHASE;
00093     }
00094     else if (time_since_birth < GetMDuration())
00095     {
00096         mCurrentCellCyclePhase = M_PHASE;
00097     }
00098     else if (time_since_birth < GetMDuration() + mG1Duration)
00099     {
00100         mCurrentCellCyclePhase = G_ONE_PHASE;
00101     }
00102     else if (time_since_birth < GetMDuration() + mG1Duration + GetSDuration())
00103     {
00104         mCurrentCellCyclePhase = S_PHASE;
00105     }
00106     else if (time_since_birth < GetMDuration() + mG1Duration + GetSDuration() + GetG2Duration())
00107     {
00108         mCurrentCellCyclePhase = G_TWO_PHASE;
00109     }
00110 }
00111 
00112 void AbstractSimpleCellCycleModel::OutputCellCycleModelParameters(out_stream& rParamsFile)
00113 {
00114     // No new parameters to output
00115 
00116     // Call method on direct parent class
00117     AbstractCellCycleModel::OutputCellCycleModelParameters(rParamsFile);
00118 }