NhsContractionModel.hpp

/*

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*/
#ifndef NHSCONTRACTIONMODEL_HPP_
#define NHSCONTRACTIONMODEL_HPP_

#include "AbstractOdeBasedContractionModel.hpp"
#include "Exception.hpp"


class NhsContractionModel  : public AbstractOdeBasedContractionModel
{
friend class TestContractionModels;

protected :
    double mLambda;
    double mDLambdaDt;
    double mCalciumI;


    double mCalciumTrop50;

    double mK1;
    double mK2;

    // Parameters

    static const double mKon;

    static const double mKrefoff;

    static const double mGamma;

    static const double mCalciumTroponinMax;

    static const double mAlphaR1;

    static const double mAlphaR2;

    static const double mKZ;

    static const unsigned mNr;

    static const double mBeta1;

    static const double mAlpha0;

    static const unsigned mN;

    static const double mZp;

    static const double mCalcium50ref;

    static const double mTref;

    static const double mBeta0;

    static const double mA;

    static const double mA1;

    static const double mA2;

    static const double mA3;

    static const double mAlpha1;

    static const double mAlpha2;

    static const double mAlpha3;

    void CalculateCalciumTrop50();

    double CalculateT0(double z);

public :
    NhsContractionModel();

    void SetStretchAndStretchRate(double lambda, double dlambdaDt);

    void SetInputParameters(ContractionModelInputParameters& rInputParameters);

    void SetIntracellularCalciumConcentration(double calciumConcentration);

    double GetCalciumTroponinValue();

    void EvaluateYDerivatives(double time, const std::vector<double> &rY, std::vector<double> &rDY);

    double GetActiveTension();

    double GetNextActiveTension()
    {
        EXCEPTION("If using this in an 'explicit manner' call UpdateStateVariables() and then GetActiveTension(), otherwise use NhsModelWithBackwardSolver");
    }

    bool IsStretchDependent()
    {
        return true;
    }

    bool IsStretchRateDependent()
    {
        return true;
    }
};
#endif /*NHSCONTRACTIONMODEL_HPP_*/