Chaste Release::3.1
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00001 /* 00002 00003 Copyright (c) 2005-2012, University of Oxford. 00004 All rights reserved. 00005 00006 University of Oxford means the Chancellor, Masters and Scholars of the 00007 University of Oxford, having an administrative office at Wellington 00008 Square, Oxford OX1 2JD, UK. 00009 00010 This file is part of Chaste. 00011 00012 Redistribution and use in source and binary forms, with or without 00013 modification, are permitted provided that the following conditions are met: 00014 * Redistributions of source code must retain the above copyright notice, 00015 this list of conditions and the following disclaimer. 00016 * Redistributions in binary form must reproduce the above copyright notice, 00017 this list of conditions and the following disclaimer in the documentation 00018 and/or other materials provided with the distribution. 00019 * Neither the name of the University of Oxford nor the names of its 00020 contributors may be used to endorse or promote products derived from this 00021 software without specific prior written permission. 00022 00023 THIS SOFTWARE IS PROVIDED BY THE COPYRIGHT HOLDERS AND CONTRIBUTORS "AS IS" 00024 AND ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE 00025 IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE 00026 ARE DISCLAIMED. IN NO EVENT SHALL THE COPYRIGHT HOLDER OR CONTRIBUTORS BE 00027 LIABLE FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR 00028 CONSEQUENTIAL DAMAGES (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF SUBSTITUTE 00029 GOODS OR SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS INTERRUPTION) 00030 HOWEVER CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT 00031 LIABILITY, OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY OUT 00032 OF THE USE OF THIS SOFTWARE, EVEN IF ADVISED OF THE POSSIBILITY OF SUCH DAMAGE. 00033 00034 */ 00035 #include "SloughingCellKiller.hpp" 00036 #include "AbstractCentreBasedCellPopulation.hpp" 00037 #include "Exception.hpp" 00038 00039 template<unsigned DIM> 00040 SloughingCellKiller<DIM>::SloughingCellKiller(AbstractCellPopulation<DIM>* pCrypt, double sloughHeight, bool sloughSides, double sloughWidth) 00041 : AbstractCellKiller<DIM>(pCrypt), 00042 mSloughSides(sloughSides) 00043 { 00044 assert(sloughHeight > 0.0); 00045 mSloughHeight = sloughHeight; 00046 00047 assert(sloughWidth > 0.0); 00048 mSloughWidth = sloughWidth; 00049 } 00050 00051 template<unsigned DIM> 00052 bool SloughingCellKiller<DIM>::GetSloughSides() const 00053 { 00054 return mSloughSides; 00055 } 00056 00057 template<unsigned DIM> 00058 double SloughingCellKiller<DIM>::GetSloughHeight() const 00059 { 00060 return mSloughHeight; 00061 } 00062 00063 template<unsigned DIM> 00064 double SloughingCellKiller<DIM>::GetSloughWidth() const 00065 { 00066 return mSloughWidth; 00067 } 00068 00069 template<unsigned DIM> 00070 void SloughingCellKiller<DIM>::CheckAndLabelCellsForApoptosisOrDeath() 00071 { 00072 switch (DIM) 00073 { 00074 case 1: 00075 { 00076 for (typename AbstractCellPopulation<DIM>::Iterator cell_iter = this->mpCellPopulation->Begin(); 00077 cell_iter != this->mpCellPopulation->End(); 00078 ++cell_iter) 00079 { 00080 double x = this->mpCellPopulation->GetLocationOfCellCentre(*cell_iter)[0]; 00081 00082 if (x > mSloughHeight) 00083 { 00084 cell_iter->Kill(); 00085 } 00086 } 00087 break; 00088 } 00089 case 2: 00090 { 00091 for (typename AbstractCellPopulation<DIM>::Iterator cell_iter = this->mpCellPopulation->Begin(); 00092 cell_iter != this->mpCellPopulation->End(); 00093 ++cell_iter) 00094 { 00095 c_vector<double, 2> location = this->mpCellPopulation->GetLocationOfCellCentre(*cell_iter); 00096 double x = location[0]; 00097 double y = location[1]; 00098 00099 if ((y>mSloughHeight) || (mSloughSides && ((x<0.0) || (x>mSloughWidth)))) 00100 { 00101 cell_iter->Kill(); 00102 } 00103 } 00104 break; 00105 } 00106 case 3: 00107 { 00108 EXCEPTION("SloughingCellKiller is not yet implemented in 3D"); 00109 break; 00110 } 00111 default: 00112 // This can't happen 00113 NEVER_REACHED; 00114 } 00115 } 00116 00117 template<unsigned DIM> 00118 void SloughingCellKiller<DIM>::OutputCellKillerParameters(out_stream& rParamsFile) 00119 { 00120 *rParamsFile << "\t\t\t<SloughLength>" << mSloughHeight << "</SloughLength>\n"; 00121 *rParamsFile << "\t\t\t<SloughSides>" << mSloughSides << "</SloughSides>\n"; 00122 *rParamsFile << "\t\t\t<SloughWidth>" << mSloughWidth << "</SloughWidth>\n"; 00123 00124 // Call method on direct parent class 00125 AbstractCellKiller<DIM>::OutputCellKillerParameters(rParamsFile); 00126 } 00127 00129 // Explicit instantiation 00131 00132 template class SloughingCellKiller<1>; 00133 template class SloughingCellKiller<2>; 00134 template class SloughingCellKiller<3>; 00135 00136 // Serialization for Boost >= 1.36 00137 #include "SerializationExportWrapperForCpp.hpp" 00138 EXPORT_TEMPLATE_CLASS_SAME_DIMS(SloughingCellKiller)