Chaste Release::3.1
|
00001 /* 00002 00003 Copyright (c) 2005-2012, University of Oxford. 00004 All rights reserved. 00005 00006 University of Oxford means the Chancellor, Masters and Scholars of the 00007 University of Oxford, having an administrative office at Wellington 00008 Square, Oxford OX1 2JD, UK. 00009 00010 This file is part of Chaste. 00011 00012 Redistribution and use in source and binary forms, with or without 00013 modification, are permitted provided that the following conditions are met: 00014 * Redistributions of source code must retain the above copyright notice, 00015 this list of conditions and the following disclaimer. 00016 * Redistributions in binary form must reproduce the above copyright notice, 00017 this list of conditions and the following disclaimer in the documentation 00018 and/or other materials provided with the distribution. 00019 * Neither the name of the University of Oxford nor the names of its 00020 contributors may be used to endorse or promote products derived from this 00021 software without specific prior written permission. 00022 00023 THIS SOFTWARE IS PROVIDED BY THE COPYRIGHT HOLDERS AND CONTRIBUTORS "AS IS" 00024 AND ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE 00025 IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE 00026 ARE DISCLAIMED. IN NO EVENT SHALL THE COPYRIGHT HOLDER OR CONTRIBUTORS BE 00027 LIABLE FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR 00028 CONSEQUENTIAL DAMAGES (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF SUBSTITUTE 00029 GOODS OR SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS INTERRUPTION) 00030 HOWEVER CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT 00031 LIABILITY, OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY OUT 00032 OF THE USE OF THIS SOFTWARE, EVEN IF ADVISED OF THE POSSIBILITY OF SUCH DAMAGE. 00033 00034 */ 00035 00036 #include "SteadyStateRunner.hpp" 00037 00038 #ifdef CHASTE_CVODE 00039 00040 void SteadyStateRunner::RunToSteadyStateImplementation() 00041 { 00042 // Get necessary things from stimulus current 00043 boost::shared_ptr<RegularStimulus> p_reg_stim = 00044 boost::static_pointer_cast<RegularStimulus>(mpModel->GetStimulusFunction()); 00045 const double pacing_cycle_length = p_reg_stim->GetPeriod(); //ms 00046 double maximum_time_step = p_reg_stim->GetDuration(); // ms 00047 00048 // Set up vectors to monitor progress 00049 std::vector<double> old_state_vars; 00050 std::vector<double> new_state_vars; 00051 CopyToStdVector(mpModel->rGetStateVariables(),old_state_vars); 00052 00053 mpModel->SetMaxSteps(1e5); // Per pace. 00054 00055 bool rough_solution = true; 00056 //mpModel->SetTolerances(1e-4,1e-6); 00057 00058 // Use optimisations from #1912 - since we don't interfere with the model between Solve() calls don't reset. 00059 mpModel->SetAutoReset(false); 00060 00061 const unsigned num_paces_to_analyse = (mTwoPaceScan) ? 2u : 1u; 00062 const unsigned max_evaluations = (unsigned)(mMaxNumPaces/num_paces_to_analyse); // Only allow 10000 paces at the moment. 00063 for (unsigned i=0; i<max_evaluations; i++) 00064 { 00065 // Look at two paces in the hope of detecting alternans and still saying we're steady-ish. 00066 mpModel->Solve((pacing_cycle_length)*(double)(i), (pacing_cycle_length)*(double)(i+num_paces_to_analyse), maximum_time_step); 00067 this->mNumEvaluations += num_paces_to_analyse; 00068 CopyToStdVector(mpModel->rGetStateVariables(),new_state_vars); 00069 00070 // Calculate the change in the norm of the state variables 00071 double temp = 0; 00072 for (unsigned i=0; i<old_state_vars.size(); i++) 00073 { 00074 temp += fabs(new_state_vars[i] - old_state_vars[i]); 00075 } 00076 00077 if (rough_solution && temp < 1e-4) 00078 { 00079 mpModel->SetTolerances(1e-6,1e-8); 00080 rough_solution = false; 00081 } 00082 00083 if (temp < 1e-6) 00084 { 00085 break; 00086 } 00087 00088 old_state_vars = new_state_vars; 00089 } 00090 00091 // Since we don't know what we are going to do with it next re-set it on every solve call. 00092 mpModel->SetAutoReset(true); 00093 } 00094 00095 #endif // CHASTE_CVODE 00096