Chaste Release::3.1
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00001 /* 00002 00003 Copyright (c) 2005-2012, University of Oxford. 00004 All rights reserved. 00005 00006 University of Oxford means the Chancellor, Masters and Scholars of the 00007 University of Oxford, having an administrative office at Wellington 00008 Square, Oxford OX1 2JD, UK. 00009 00010 This file is part of Chaste. 00011 00012 Redistribution and use in source and binary forms, with or without 00013 modification, are permitted provided that the following conditions are met: 00014 * Redistributions of source code must retain the above copyright notice, 00015 this list of conditions and the following disclaimer. 00016 * Redistributions in binary form must reproduce the above copyright notice, 00017 this list of conditions and the following disclaimer in the documentation 00018 and/or other materials provided with the distribution. 00019 * Neither the name of the University of Oxford nor the names of its 00020 contributors may be used to endorse or promote products derived from this 00021 software without specific prior written permission. 00022 00023 THIS SOFTWARE IS PROVIDED BY THE COPYRIGHT HOLDERS AND CONTRIBUTORS "AS IS" 00024 AND ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE 00025 IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE 00026 ARE DISCLAIMED. IN NO EVENT SHALL THE COPYRIGHT HOLDER OR CONTRIBUTORS BE 00027 LIABLE FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR 00028 CONSEQUENTIAL DAMAGES (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF SUBSTITUTE 00029 GOODS OR SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS INTERRUPTION) 00030 HOWEVER CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT 00031 LIABILITY, OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY OUT 00032 OF THE USE OF THIS SOFTWARE, EVEN IF ADVISED OF THE POSSIBILITY OF SUCH DAMAGE. 00033 00034 */ 00035 00036 #include "VolumeDependentAveragedSourcePde.hpp" 00037 #include "ApoptoticCellProperty.hpp" 00038 00039 template<unsigned DIM> 00040 VolumeDependentAveragedSourcePde<DIM>::VolumeDependentAveragedSourcePde(AbstractCellPopulation<DIM>& rCellPopulation, double coefficient) 00041 : AveragedSourcePde<DIM>(rCellPopulation, coefficient) 00042 { 00043 assert(dynamic_cast<NodeBasedCellPopulation<DIM>*>(&(this->mrCellPopulation))); 00044 mpStaticCastCellPopulation = static_cast<NodeBasedCellPopulation<DIM>*>(&(this->mrCellPopulation)); 00045 } 00046 00047 template<unsigned DIM> 00048 void VolumeDependentAveragedSourcePde<DIM>::SetupSourceTerms(TetrahedralMesh<DIM,DIM>& rCoarseMesh, std::map< CellPtr, unsigned >* pCellPdeElementMap) // must be called before solve 00049 { 00050 // Allocate memory 00051 this->mCellDensityOnCoarseElements.resize(rCoarseMesh.GetNumElements()); 00052 for (unsigned elem_index=0; elem_index<this->mCellDensityOnCoarseElements.size(); elem_index++) 00053 { 00054 this->mCellDensityOnCoarseElements[elem_index] = 0.0; 00055 } 00056 00057 // Loop over cells, find which coarse element it is in, and add volume to the mSourceTermOnCoarseElements[elem_index]; 00058 for (typename AbstractCellPopulation<DIM>::Iterator cell_iter = this->mrCellPopulation.Begin(); 00059 cell_iter != this->mrCellPopulation.End(); 00060 ++cell_iter) 00061 { 00062 unsigned elem_index = 0; 00063 const ChastePoint<DIM>& r_position_of_cell = this->mrCellPopulation.GetLocationOfCellCentre(*cell_iter); 00064 00065 if (pCellPdeElementMap != NULL) 00066 { 00067 elem_index = (*pCellPdeElementMap)[*cell_iter]; 00068 } 00069 else 00070 { 00071 elem_index = rCoarseMesh.GetContainingElementIndex(r_position_of_cell); 00072 } 00073 00074 unsigned node_index = this->mrCellPopulation.GetLocationIndexUsingCell(*cell_iter); 00075 00076 // Uptake normalised to 1 for unit cell 00077 double radius = mpStaticCastCellPopulation->rGetMesh().GetCellRadius(node_index); 00078 double cell_weight = radius*radius; 00079 00080 bool cell_is_apoptotic = cell_iter->template HasCellProperty<ApoptoticCellProperty>(); 00081 if (!cell_is_apoptotic) 00082 { 00083 this->mCellDensityOnCoarseElements[elem_index] += cell_weight; 00084 } 00085 } 00086 00087 // Then divide each entry of mSourceTermOnCoarseElements by the element's area 00088 c_matrix<double, DIM, DIM> jacobian; 00089 double det; 00090 for (unsigned elem_index=0; elem_index<this->mCellDensityOnCoarseElements.size(); elem_index++) 00091 { 00092 rCoarseMesh.GetElement(elem_index)->CalculateJacobian(jacobian, det); 00093 this->mCellDensityOnCoarseElements[elem_index] /= rCoarseMesh.GetElement(elem_index)->GetVolume(det); 00094 } 00095 } 00096 00098 // Explicit instantiation 00100 00101 template class VolumeDependentAveragedSourcePde<1>; 00102 template class VolumeDependentAveragedSourcePde<2>; 00103 template class VolumeDependentAveragedSourcePde<3>; 00104 00105 // Serialization for Boost >= 1.36 00106 #include "SerializationExportWrapperForCpp.hpp" 00107 EXPORT_TEMPLATE_CLASS_SAME_DIMS(VolumeDependentAveragedSourcePde)