00001 /* 00002 00003 Copyright (c) 2005-2015, University of Oxford. 00004 All rights reserved. 00005 00006 University of Oxford means the Chancellor, Masters and Scholars of the 00007 University of Oxford, having an administrative office at Wellington 00008 Square, Oxford OX1 2JD, UK. 00009 00010 This file is part of Chaste. 00011 00012 Redistribution and use in source and binary forms, with or without 00013 modification, are permitted provided that the following conditions are met: 00014 * Redistributions of source code must retain the above copyright notice, 00015 this list of conditions and the following disclaimer. 00016 * Redistributions in binary form must reproduce the above copyright notice, 00017 this list of conditions and the following disclaimer in the documentation 00018 and/or other materials provided with the distribution. 00019 * Neither the name of the University of Oxford nor the names of its 00020 contributors may be used to endorse or promote products derived from this 00021 software without specific prior written permission. 00022 00023 THIS SOFTWARE IS PROVIDED BY THE COPYRIGHT HOLDERS AND CONTRIBUTORS "AS IS" 00024 AND ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE 00025 IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE 00026 ARE DISCLAIMED. IN NO EVENT SHALL THE COPYRIGHT HOLDER OR CONTRIBUTORS BE 00027 LIABLE FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR 00028 CONSEQUENTIAL DAMAGES (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF SUBSTITUTE 00029 GOODS OR SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS INTERRUPTION) 00030 HOWEVER CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT 00031 LIABILITY, OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY OUT 00032 OF THE USE OF THIS SOFTWARE, EVEN IF ADVISED OF THE POSSIBILITY OF SUCH DAMAGE. 00033 00034 */ 00035 00036 #ifndef ABSTRACTGENERALIZEDRUSHLARSENCARDIACCELL_HPP_ 00037 #define ABSTRACTGENERALIZEDRUSHLARSENCARDIACCELL_HPP_ 00038 00039 #include "ChasteSerialization.hpp" 00040 #include <boost/serialization/base_object.hpp> 00041 #include "ClassIsAbstract.hpp" 00042 #include "AbstractCardiacCell.hpp" 00043 #include "PetscTools.hpp" 00044 00045 /* 00046 Megan E. Marsh, Raymond J. Spiteri 00047 Numerical Simulation Laboratory 00048 University of Saskatchewan 00049 December 2011 00050 Partial support provided by research grants from the National 00051 Science and Engineering Research Council (NSERC) of Canada 00052 and the MITACS/Mprime Canadian Network of Centres of Excellence. 00053 */ 00054 00059 class AbstractGeneralizedRushLarsenCardiacCell : public AbstractCardiacCell 00060 { 00061 private: 00063 friend class boost::serialization::access; 00070 template<class Archive> 00071 void serialize(Archive & archive, const unsigned int version) 00072 { 00073 // This calls serialize on the base class. 00074 archive & boost::serialization::base_object<AbstractCardiacCell>(*this); 00075 } 00076 00077 public: 00091 AbstractGeneralizedRushLarsenCardiacCell( 00092 unsigned numberOfStateVariables, 00093 unsigned voltageIndex, 00094 boost::shared_ptr<AbstractStimulusFunction> pIntracellularStimulus); 00095 00097 virtual ~AbstractGeneralizedRushLarsenCardiacCell(); 00098 00110 OdeSolution Compute(double tStart, double tEnd, double tSamp=0.0); 00111 00122 void ComputeExceptVoltage(double tStart, double tEnd); 00123 00131 void SolveAndUpdateState(double tStart, double tEnd); 00132 00133 00137 bool HasAnalyticJacobian() const; 00138 00145 void ForceUseOfNumericalJacobian(bool useNumericalJacobian = true); 00146 00147 00148 private: 00149 #define COVERAGE_IGNORE 00150 00157 void EvaluateYDerivatives(double time, const std::vector<double>& rY, std::vector<double>& rDY) 00158 { 00159 NEVER_REACHED; 00160 } 00161 #undef COVERAGE_IGNORE 00162 00163 protected: 00169 virtual void ComputeOneStepExceptVoltage(double time)=0; 00170 00176 virtual void UpdateTransmembranePotential(double time)=0; 00177 00179 std::vector<double> mPartialF; 00180 00182 std::vector<double> mEvalF; 00183 00185 std::vector<double> mYInit; 00186 00188 bool mHasAnalyticJacobian; 00189 }; 00190 00191 CLASS_IS_ABSTRACT(AbstractGeneralizedRushLarsenCardiacCell) 00192 00193 #endif // ABSTRACTGENERALIZEDRUSHLARSENCARDIACCELL_HPP_