AbstractGeneralizedRushLarsenCardiacCell.hpp

00001 /*
00002 
00003 Copyright (c) 2005-2015, University of Oxford.
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00008 Square, Oxford OX1 2JD, UK.
00009 
00010 This file is part of Chaste.
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00015    this list of conditions and the following disclaimer.
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00023 THIS SOFTWARE IS PROVIDED BY THE COPYRIGHT HOLDERS AND CONTRIBUTORS "AS IS"
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00034 */
00035 
00036 #ifndef ABSTRACTGENERALIZEDRUSHLARSENCARDIACCELL_HPP_
00037 #define ABSTRACTGENERALIZEDRUSHLARSENCARDIACCELL_HPP_
00038 
00039 #include "ChasteSerialization.hpp"
00040 #include <boost/serialization/base_object.hpp>
00041 #include "ClassIsAbstract.hpp"
00042 #include "AbstractCardiacCell.hpp"
00043 #include "PetscTools.hpp"
00044 
00045 /*
00046 Megan E. Marsh, Raymond J. Spiteri
00047 Numerical Simulation Laboratory
00048 University of Saskatchewan
00049 December 2011
00050 Partial support provided by research grants from the National
00051 Science and Engineering Research Council (NSERC) of Canada
00052 and the MITACS/Mprime Canadian Network of Centres of Excellence.
00053 */
00054 
00059 class AbstractGeneralizedRushLarsenCardiacCell : public AbstractCardiacCell
00060 {
00061 private:
00063     friend class boost::serialization::access;
00070     template<class Archive>
00071     void serialize(Archive & archive, const unsigned int version)
00072     {
00073         // This calls serialize on the base class.
00074         archive & boost::serialization::base_object<AbstractCardiacCell>(*this);
00075     }
00076 
00077 public:
00091     AbstractGeneralizedRushLarsenCardiacCell(
00092             unsigned numberOfStateVariables,
00093             unsigned voltageIndex,
00094             boost::shared_ptr<AbstractStimulusFunction> pIntracellularStimulus);
00095 
00097     virtual ~AbstractGeneralizedRushLarsenCardiacCell();
00098 
00110     OdeSolution Compute(double tStart, double tEnd, double tSamp=0.0);
00111 
00122     void ComputeExceptVoltage(double tStart, double tEnd);
00123 
00131     void SolveAndUpdateState(double tStart, double tEnd);
00132 
00133 
00137     bool HasAnalyticJacobian() const;
00138 
00145     void ForceUseOfNumericalJacobian(bool useNumericalJacobian = true);
00146 
00147 
00148 private:
00149 #define COVERAGE_IGNORE
00150 
00157     void EvaluateYDerivatives(double time, const std::vector<double>& rY, std::vector<double>& rDY)
00158     {
00159         NEVER_REACHED;
00160     }
00161 #undef COVERAGE_IGNORE
00162 
00163 protected:
00169     virtual void ComputeOneStepExceptVoltage(double time)=0;
00170 
00176     virtual void UpdateTransmembranePotential(double time)=0;
00177 
00179     std::vector<double> mPartialF;
00180 
00182     std::vector<double> mEvalF;
00183 
00185     std::vector<double> mYInit;
00186 
00188     bool mHasAnalyticJacobian;
00189 };
00190 
00191 CLASS_IS_ABSTRACT(AbstractGeneralizedRushLarsenCardiacCell)
00192 
00193 #endif // ABSTRACTGENERALIZEDRUSHLARSENCARDIACCELL_HPP_

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