AbstractSimpleCellCycleModel.cpp

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#include "AbstractSimpleCellCycleModel.hpp"
#include "Exception.hpp"
#include "StemCellProliferativeType.hpp"
#include "TransitCellProliferativeType.hpp"
#include "DifferentiatedCellProliferativeType.hpp"

AbstractSimpleCellCycleModel::AbstractSimpleCellCycleModel()
{
}

AbstractSimpleCellCycleModel::~AbstractSimpleCellCycleModel()
{
}

void AbstractSimpleCellCycleModel::Initialise()
{
    SetG1Duration();
}

void AbstractSimpleCellCycleModel::InitialiseDaughterCell()
{
    AbstractCellCycleModel::InitialiseDaughterCell();
    SetG1Duration();
}

void AbstractSimpleCellCycleModel::SetG1Duration()
{
    assert(mpCell != NULL);

    if (mpCell->GetCellProliferativeType()->IsType<StemCellProliferativeType>())
    {
        mG1Duration = GetStemCellG1Duration();
    }
    else if (mpCell->GetCellProliferativeType()->IsType<TransitCellProliferativeType>())
    {
        mG1Duration = GetTransitCellG1Duration();
    }
    else if (mpCell->GetCellProliferativeType()->IsType<DifferentiatedCellProliferativeType>())
    {
        mG1Duration = DBL_MAX;
    }
    else
    {
        NEVER_REACHED;
    }
}

void AbstractSimpleCellCycleModel::ResetForDivision()
{
    AbstractCellCycleModel::ResetForDivision();
    mBirthTime = SimulationTime::Instance()->GetTime();
    SetG1Duration();
}

void AbstractSimpleCellCycleModel::UpdateCellCyclePhase()
{
    double time_since_birth = GetAge();
    assert(time_since_birth >= 0);

    if (mpCell->GetCellProliferativeType()->IsType<DifferentiatedCellProliferativeType>())
    {
        mCurrentCellCyclePhase = G_ZERO_PHASE;
    }
    else if (time_since_birth < GetMDuration())
    {
        mCurrentCellCyclePhase = M_PHASE;
    }
    else if (time_since_birth < GetMDuration() + mG1Duration)
    {
        mCurrentCellCyclePhase = G_ONE_PHASE;
    }
    else if (time_since_birth < GetMDuration() + mG1Duration + GetSDuration())
    {
        mCurrentCellCyclePhase = S_PHASE;
    }
    else if (time_since_birth < GetMDuration() + mG1Duration + GetSDuration() + GetG2Duration())
    {
        mCurrentCellCyclePhase = G_TWO_PHASE;
    }
}

void AbstractSimpleCellCycleModel::OutputCellCycleModelParameters(out_stream& rParamsFile)
{
    // No new parameters to output

    // Call method on direct parent class
    AbstractCellCycleModel::OutputCellCycleModelParameters(rParamsFile);
}