Chaste  Release::3.4
AbstractWntOdeBasedCellCycleModel.cpp
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34 */
35 #include "AbstractWntOdeBasedCellCycleModel.hpp"
36 #include "Exception.hpp"
37 
38 AbstractWntOdeBasedCellCycleModel::AbstractWntOdeBasedCellCycleModel(boost::shared_ptr<AbstractCellCycleModelOdeSolver> pOdeSolver)
39  : AbstractOdeBasedCellCycleModel(SimulationTime::Instance()->GetTime(), pOdeSolver)
40 {
41 }
42 
44 {
45 }
46 
48 {
49  assert(mpCell != NULL);
50  double level = 0;
51 
52  switch (mDimension)
53  {
54  case 1:
55  {
56  const unsigned DIM = 1;
58  break;
59  }
60  case 2:
61  {
62  const unsigned DIM = 2;
64  break;
65  }
66  case 3:
67  {
68  const unsigned DIM = 3;
70  break;
71  }
72  default:
74  }
75 
76  return level;
77 }
78 
80 {
82 
83  assert(mpOdeSystem != NULL);
84 
85  // This model needs the protein concentrations and phase resetting to G0/G1.
86  // Keep the Wnt pathway in the same state but reset the cell cycle part
87  // Cell cycle is proteins 0 to 4 (first 5 ODEs)
88  std::vector<double> init_conds = mpOdeSystem->GetInitialConditions();
89  for (unsigned i=0; i<5; i++)
90  {
91  mpOdeSystem->rGetStateVariables()[i] = init_conds[i];
92  }
93 }
94 
96 {
98  if (SimulationTime::Instance()->GetTime() == mLastTime
99  || GetOdeStopTime() == mLastTime)
100  {
101  // Should only be called if we're still running ODEs
103  }
104 }
105 
107 {
108  assert(mpOdeSystem != NULL);
109  assert(mpCell != NULL);
111 }
112 
114 {
115  return 16.0;
116 }
117 
119 {
120  return 16.0;
121 }
122 
124 {
125  return false;
126 }
127 
129 {
130  // No new parameters to output
131 
132  // Call method on direct parent class
134 }
135 
virtual void ChangeCellProliferativeTypeDueToCurrentBetaCateninLevel()=0
double GetWntLevel(double height)
static SimulationTime * Instance()
virtual void OutputCellCycleModelParameters(out_stream &rParamsFile)
#define NEVER_REACHED
Definition: Exception.hpp:206
AbstractWntOdeBasedCellCycleModel(boost::shared_ptr< AbstractCellCycleModelOdeSolver > pOdeSolver=boost::shared_ptr< AbstractCellCycleModelOdeSolver >())
static WntConcentration * Instance()
virtual void OutputCellCycleModelParameters(out_stream &rParamsFile)