Chaste Commit::ca8ccdedf819b6e02855bc0e8e6f50bdecbc5208
WelikyOsterForce.cpp
1/*
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34*/
35
36#include "WelikyOsterForce.hpp"
37
38template<unsigned DIM>
40 : AbstractForce<DIM>(),
41 mWelikyOsterAreaParameter(1.0),
42 mWelikyOsterPerimeterParameter(1.0)
43{
44}
45
46template<unsigned DIM>
50
51template <unsigned DIM>
53{
54 // This method only works in 2D at present
55 if constexpr (DIM == 2)
56 {
57 // Throw an exception message if not using a VertexBasedCellPopulation
58 if (dynamic_cast<VertexBasedCellPopulation<DIM>*>(&rCellPopulation) == nullptr)
59 {
60 EXCEPTION("WelikyOsterForce is to be used with a VertexBasedCellPopulation only");
61 }
62
63 // Helper variable that is a static cast of the cell population
64 VertexBasedCellPopulation<DIM>* p_cell_population = static_cast<VertexBasedCellPopulation<DIM>*>(&rCellPopulation);
65
66 /*
67 * The force on each node is given by the interaction between the area and
68 * the perimeter of the element containing the node.
69 */
70
71 // Iterate over elements in the cell population
72 for (typename VertexMesh<DIM,DIM>::VertexElementIterator element_iter = p_cell_population->rGetMesh().GetElementIteratorBegin();
73 element_iter != p_cell_population->rGetMesh().GetElementIteratorEnd();
74 ++element_iter)
75 {
76 unsigned element_index = element_iter->GetIndex();
77
78 /******** Start of deformation force calculation ********/
79
80 // Compute the area of this element
81 double element_area = p_cell_population->rGetMesh().GetVolumeOfElement(element_index);
82
83 double deformation_coefficient = GetWelikyOsterAreaParameter()/element_area;
84
85 /******** End of deformation force calculation *************/
86
87 /******** Start of membrane force calculation ***********/
88
89 // Compute the perimeter of the element
90 double element_perimeter = p_cell_population->rGetMesh().GetSurfaceAreaOfElement(element_index);
91
92 double membrane_surface_tension_coefficient = GetWelikyOsterPerimeterParameter()*element_perimeter;
93
94 /******** End of membrane force calculation **********/
95
96 unsigned num_nodes = element_iter->GetNumNodes();
97 for (unsigned node_local_index = 0; node_local_index < num_nodes; node_local_index++)
98 {
99 unsigned node_global_index = element_iter->GetNodeGlobalIndex(node_local_index);
100
101 c_vector<double, DIM> current_node = element_iter->GetNodeLocation(node_local_index);
102 c_vector<double, DIM> next_node = element_iter->GetNodeLocation((node_local_index + 1)%(element_iter->GetNumNodes()));
103 c_vector<double, DIM> previous_node = element_iter->GetNodeLocation((node_local_index + element_iter->GetNumNodes() - 1)%(element_iter->GetNumNodes()));
104
105 c_vector<double, DIM> clockwise_unit_vector = p_cell_population->rGetMesh().GetVectorFromAtoB(current_node, previous_node);
106 clockwise_unit_vector /= norm_2(clockwise_unit_vector);
107
108 c_vector<double, DIM> anti_clockwise_unit_vector = p_cell_population->rGetMesh().GetVectorFromAtoB(current_node, next_node);
109 anti_clockwise_unit_vector /= norm_2(anti_clockwise_unit_vector);
110
111 // Calculate the outward normal at the node
112 c_vector<double, DIM> outward_normal = -0.5*clockwise_unit_vector - 0.5*anti_clockwise_unit_vector;
113 outward_normal /= norm_2(outward_normal);
114
115 c_vector<double, DIM> deformation_contribution = deformation_coefficient * outward_normal;
116
117 c_vector<double, DIM> membrane_surface_tension_contribution = membrane_surface_tension_coefficient * (clockwise_unit_vector + anti_clockwise_unit_vector);
118
119 c_vector<double, DIM> force_on_node = deformation_contribution + membrane_surface_tension_contribution;
120
121 p_cell_population->GetNode(node_global_index)->AddAppliedForceContribution(force_on_node);
122 }
123 }
124 }
125 else
126 {
128 }
129}
130
131template<unsigned DIM>
133{
134 return mWelikyOsterAreaParameter;
135}
136
137template<unsigned DIM>
139{
140 return mWelikyOsterPerimeterParameter;
141}
142
143template<unsigned DIM>
144void WelikyOsterForce<DIM>::SetWelikyOsterAreaParameter(double welikyOsterAreaParameter)
145{
146 mWelikyOsterAreaParameter = welikyOsterAreaParameter;
147}
148
149template<unsigned DIM>
150void WelikyOsterForce<DIM>::SetWelikyOsterPerimeterParameter(double welikyOsterPerimeterParameter)
151{
152 mWelikyOsterPerimeterParameter = welikyOsterPerimeterParameter;
153}
154
155template<unsigned DIM>
157{
158 *rParamsFile << "\t\t\t<WelikyOsterAreaParameter>" << mWelikyOsterAreaParameter << "</WelikyOsterAreaParameter>\n";
159 *rParamsFile << "\t\t\t<WelikyOsterPerimeterParameter>" << mWelikyOsterPerimeterParameter << "</WelikyOsterPerimeterParameter>\n";
160
161 // Call method on direct parent class
163}
164
165// Explicit instantiation
166template class WelikyOsterForce<1>;
167template class WelikyOsterForce<2>;
168template class WelikyOsterForce<3>;
169
170// Serialization for Boost >= 1.36
#define EXCEPTION(message)
#define NEVER_REACHED
#define EXPORT_TEMPLATE_CLASS_SAME_DIMS(CLASS)
virtual void OutputForceParameters(out_stream &rParamsFile)=0
void AddAppliedForceContribution(const c_vector< double, SPACE_DIM > &rForceContribution)
Definition Node.cpp:224
MutableVertexMesh< DIM, DIM > & rGetMesh()
Node< DIM > * GetNode(unsigned index)
virtual c_vector< double, SPACE_DIM > GetVectorFromAtoB(const c_vector< double, SPACE_DIM > &rLocationA, const c_vector< double, SPACE_DIM > &rLocationB)
VertexElementIterator GetElementIteratorEnd()
virtual double GetSurfaceAreaOfElement(unsigned index)
VertexElementIterator GetElementIteratorBegin(bool skipDeletedElements=true)
virtual double GetVolumeOfElement(unsigned index)
void SetWelikyOsterPerimeterParameter(double welikyOsterPerimeterParameter)
void AddForceContribution(AbstractCellPopulation< DIM > &rCellPopulation)
void SetWelikyOsterAreaParameter(double welikyOsterAreaParameter)
void OutputForceParameters(out_stream &rParamsFile)
double GetWelikyOsterAreaParameter()
double GetWelikyOsterPerimeterParameter()