LuoRudyIModel1991OdeSystem Class Reference

#include <LuoRudyIModel1991OdeSystem.hpp>

Inheritance diagram for LuoRudyIModel1991OdeSystem:

Collaboration diagram for LuoRudyIModel1991OdeSystem:

List of all members.

Public Member Functions

LuoRudyIModel1991OdeSystem (boost::shared_ptr< AbstractIvpOdeSolver > pSolver, boost::shared_ptr< AbstractStimulusFunction > pIntracellularStimulus)

~LuoRudyIModel1991OdeSystem ()

void EvaluateYDerivatives (double time, const std::vector< double > &rY, std::vector< double > &rDY)

double GetIIonic ()

double GetIntracellularCalciumConcentration ()

Private Member Functions

template<class Archive>

void serialize (Archive &archive, const unsigned int version)

void VerifyStateVariables ()

Private Attributes

double fast_sodium_current_E_Na

Static Private Attributes

static const double membrane_C = 1.0

static const double membrane_F = 96484.6

static const double membrane_R = 8314

static const double membrane_T = 310.0

static const double background_current_E_b = -59.87

static const double background_current_g_b = 0.03921

static const double fast_sodium_current_g_Na = 23.0

static const double ionic_concentrations_Ki = 145.0

static const double ionic_concentrations_Ko = 5.4

static const double ionic_concentrations_Nai = 18.0

static const double ionic_concentrations_Nao = 140.0

static const double plateau_potassium_current_g_Kp = 0.0183

static const double time_dependent_potassium_current_PR_NaK = 0.01833

Friends

class boost::serialization::access

Detailed Description

This class sets up the LuoRudyIModel1991OdeSystem system of equations.

Definition at line 44 of file LuoRudyIModel1991OdeSystem.hpp.

Constructor & Destructor Documentation

LuoRudyIModel1991OdeSystem::LuoRudyIModel1991OdeSystem	(	boost::shared_ptr< AbstractIvpOdeSolver >	pSolver,
		boost::shared_ptr< AbstractStimulusFunction >	pIntracellularStimulus
	)

Constructor

Parameters:

	pSolver	is a pointer to the ODE solver
	pIntracellularStimulus	is a pointer to the intracellular stimulus

Constructor

Definition at line 57 of file LuoRudyIModel1991OdeSystem.cpp.

References fast_sodium_current_E_Na, AbstractCardiacCell::Init(), OdeSystemInformation< ODE_SYSTEM >::Instance(), ionic_concentrations_Nai, ionic_concentrations_Nao, membrane_F, membrane_R, membrane_T, and AbstractOdeSystem::mpSystemInfo.

LuoRudyIModel1991OdeSystem::~LuoRudyIModel1991OdeSystem ( void )

Destructor

Definition at line 74 of file LuoRudyIModel1991OdeSystem.cpp.

Member Function Documentation

template<class Archive>

void LuoRudyIModel1991OdeSystem::serialize	(	Archive &	archive,
		const unsigned int	version
	)			`[inline, private]`

Archive the member variables.

Parameters:

	archive
	version

Reimplemented from AbstractCardiacCell.

Definition at line 56 of file LuoRudyIModel1991OdeSystem.hpp.

void LuoRudyIModel1991OdeSystem::VerifyStateVariables ( ) [private, virtual]

Range-checking on the current values of the state variables. Make sure all gating variables have are within zero and one, and all concentrations are positive

Reimplemented from AbstractCardiacCell.

Definition at line 277 of file LuoRudyIModel1991OdeSystem.cpp.

References AbstractOdeSystem::DumpState(), and AbstractOdeSystem::rGetStateVariables().

void LuoRudyIModel1991OdeSystem::EvaluateYDerivatives	(	double	time,
		const std::vector< double > &	rY,
		std::vector< double > &	rDY
	)			`[virtual]`

Fill in a vector representing the RHS of the TenTusscher2006 system of Odes at each time step, y' = [y1' ... yn']. Some ODE solver will call this function repeatedly to solve for y = [y1 ... yn].

Parameters:

	time	the current time, in milliseconds
	rY	current values of the state variables
	rDY	to be filled in with derivatives

Fill in a vector representing the RHS of the LuoRudyIModel1991OdeSystem system of Odes at each time step, y' = [y1' ... yn']. Some ODE solver will call this function repeatedly to solve for y = [y1 ... yn].

Parameters:

	time	the current time, in milliseconds
	rY	current values of the state variables
	rDY	to be filled in with derivatives

Implements AbstractOdeSystem.

Definition at line 92 of file LuoRudyIModel1991OdeSystem.cpp.

References background_current_E_b, background_current_g_b, fast_sodium_current_E_Na, fast_sodium_current_g_Na, AbstractCardiacCell::GetStimulus(), ionic_concentrations_Ki, ionic_concentrations_Ko, ionic_concentrations_Nai, ionic_concentrations_Nao, membrane_C, membrane_F, membrane_R, membrane_T, AbstractCardiacCell::mSetVoltageDerivativeToZero, plateau_potassium_current_g_Kp, and time_dependent_potassium_current_PR_NaK.

double LuoRudyIModel1991OdeSystem::GetIIonic ( ) [virtual]

Returns the ionic current

Returns:: the total ionic current

Implements AbstractCardiacCell.

Definition at line 221 of file LuoRudyIModel1991OdeSystem.cpp.

References background_current_E_b, background_current_g_b, fast_sodium_current_E_Na, fast_sodium_current_g_Na, ionic_concentrations_Ki, ionic_concentrations_Ko, ionic_concentrations_Nai, ionic_concentrations_Nao, membrane_F, membrane_R, membrane_T, AbstractOdeSystem::mStateVariables, plateau_potassium_current_g_Kp, and time_dependent_potassium_current_PR_NaK.

double LuoRudyIModel1991OdeSystem::GetIntracellularCalciumConcentration ( ) [virtual]

Get the intracellular calcium concentration

Returns:: the intracellular calcium concentration

Reimplemented from AbstractCardiacCell.

Definition at line 78 of file LuoRudyIModel1991OdeSystem.cpp.

References AbstractOdeSystem::mStateVariables.

Friends And Related Function Documentation

friend class boost::serialization::access [friend]

Needed for serialization.

Reimplemented from AbstractCardiacCell.

Definition at line 48 of file LuoRudyIModel1991OdeSystem.hpp.

Member Data Documentation

const double LuoRudyIModel1991OdeSystem::membrane_C = 1.0 [static, private]

Constants for the LuoRudyIModel1991OdeSystem model membrane capcaitance

Definition at line 64 of file LuoRudyIModel1991OdeSystem.hpp.

Referenced by EvaluateYDerivatives().

const double LuoRudyIModel1991OdeSystem::membrane_F = 96484.6 [static, private]

Faraday constant

Definition at line 66 of file LuoRudyIModel1991OdeSystem.hpp.

Referenced by EvaluateYDerivatives(), GetIIonic(), and LuoRudyIModel1991OdeSystem().

const double LuoRudyIModel1991OdeSystem::membrane_R = 8314 [static, private]

Universal gas constant

Definition at line 68 of file LuoRudyIModel1991OdeSystem.hpp.

Referenced by EvaluateYDerivatives(), GetIIonic(), and LuoRudyIModel1991OdeSystem().

const double LuoRudyIModel1991OdeSystem::membrane_T = 310.0 [static, private]

Temeperature

Definition at line 70 of file LuoRudyIModel1991OdeSystem.hpp.

Referenced by EvaluateYDerivatives(), GetIIonic(), and LuoRudyIModel1991OdeSystem().

const double LuoRudyIModel1991OdeSystem::background_current_E_b = -59.87 [static, private]

Reversal potentila for background current

Definition at line 72 of file LuoRudyIModel1991OdeSystem.hpp.

Referenced by EvaluateYDerivatives(), and GetIIonic().

const double LuoRudyIModel1991OdeSystem::background_current_g_b = 0.03921 [static, private]

Maximal conductance for background current

Definition at line 74 of file LuoRudyIModel1991OdeSystem.hpp.

Referenced by EvaluateYDerivatives(), and GetIIonic().

const double LuoRudyIModel1991OdeSystem::fast_sodium_current_g_Na = 23.0 [static, private]

Maximal conductance for sodium current

Definition at line 76 of file LuoRudyIModel1991OdeSystem.hpp.

Referenced by EvaluateYDerivatives(), and GetIIonic().

const double LuoRudyIModel1991OdeSystem::ionic_concentrations_Ki = 145.0 [static, private]

Intracellular potassium concentration

Definition at line 78 of file LuoRudyIModel1991OdeSystem.hpp.

Referenced by EvaluateYDerivatives(), and GetIIonic().

const double LuoRudyIModel1991OdeSystem::ionic_concentrations_Ko = 5.4 [static, private]

Extracellular potassium concentration

Definition at line 80 of file LuoRudyIModel1991OdeSystem.hpp.

Referenced by EvaluateYDerivatives(), and GetIIonic().

const double LuoRudyIModel1991OdeSystem::ionic_concentrations_Nai = 18.0 [static, private]

Intracellular sodium concentration

Definition at line 82 of file LuoRudyIModel1991OdeSystem.hpp.

Referenced by EvaluateYDerivatives(), GetIIonic(), and LuoRudyIModel1991OdeSystem().

const double LuoRudyIModel1991OdeSystem::ionic_concentrations_Nao = 140.0 [static, private]

Extracellular sodium concentration

Definition at line 84 of file LuoRudyIModel1991OdeSystem.hpp.

Referenced by EvaluateYDerivatives(), GetIIonic(), and LuoRudyIModel1991OdeSystem().

const double LuoRudyIModel1991OdeSystem::plateau_potassium_current_g_Kp = 0.0183 [static, private]

Maximal conductance for plateau current

Definition at line 86 of file LuoRudyIModel1991OdeSystem.hpp.

Referenced by EvaluateYDerivatives(), and GetIIonic().

const double LuoRudyIModel1991OdeSystem::time_dependent_potassium_current_PR_NaK = 0.01833 [static, private]

Permeability ratio Na/K for potassium currents

Definition at line 88 of file LuoRudyIModel1991OdeSystem.hpp.

Referenced by EvaluateYDerivatives(), and GetIIonic().

double LuoRudyIModel1991OdeSystem::fast_sodium_current_E_Na [private]

Another parameter, which is a function of the above

Definition at line 91 of file LuoRudyIModel1991OdeSystem.hpp.

Referenced by EvaluateYDerivatives(), GetIIonic(), and LuoRudyIModel1991OdeSystem().

The documentation for this class was generated from the following files:

/tmp/release_1.1/heart/src/odes/LuoRudyIModel1991OdeSystem.hpp
/tmp/release_1.1/heart/src/odes/LuoRudyIModel1991OdeSystem.cpp


Public Member Functions
	LuoRudyIModel1991OdeSystem (boost::shared_ptr< AbstractIvpOdeSolver > pSolver, boost::shared_ptr< AbstractStimulusFunction > pIntracellularStimulus)
	~LuoRudyIModel1991OdeSystem ()
void	EvaluateYDerivatives (double time, const std::vector< double > &rY, std::vector< double > &rDY)
double	GetIIonic ()
double	GetIntracellularCalciumConcentration ()
Private Member Functions
template<class Archive>
void	serialize (Archive &archive, const unsigned int version)
void	VerifyStateVariables ()
Private Attributes
double	fast_sodium_current_E_Na
Static Private Attributes
static const double	membrane_C = 1.0
static const double	membrane_F = 96484.6
static const double	membrane_R = 8314
static const double	membrane_T = 310.0
static const double	background_current_E_b = -59.87
static const double	background_current_g_b = 0.03921
static const double	fast_sodium_current_g_Na = 23.0
static const double	ionic_concentrations_Ki = 145.0
static const double	ionic_concentrations_Ko = 5.4
static const double	ionic_concentrations_Nai = 18.0
static const double	ionic_concentrations_Nao = 140.0
static const double	plateau_potassium_current_g_Kp = 0.0183
static const double	time_dependent_potassium_current_PR_NaK = 0.01833
Friends
class	boost::serialization::access