CellCycleTimesGenerator.cpp

/*

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*/

#include "Exception.hpp"
#include "CellCycleTimesGenerator.hpp"

CellCycleTimesGenerator* CellCycleTimesGenerator::mpInstance = NULL;

CellCycleTimesGenerator::CellCycleTimesGenerator()
    : mRandomSeed(0u),
      mCurrentIndex(0u),
      mRate(1.0/2.0),
      mVectorCreated(false)
{
    assert(mpInstance == NULL); // Ensure correct serialization
}

CellCycleTimesGenerator* CellCycleTimesGenerator::Instance()
{
    if (mpInstance == NULL)
    {
        mpInstance = new CellCycleTimesGenerator();
    }
    return mpInstance;
}

void CellCycleTimesGenerator::Destroy()
{
    if (mpInstance)
    {
        delete mpInstance;
        mpInstance = NULL;
    }
}

void CellCycleTimesGenerator::SetRandomSeed(unsigned randomSeed)
{
    mRandomSeed = randomSeed;
}

unsigned CellCycleTimesGenerator::GetRandomSeed()
{
    return mRandomSeed;
}

void CellCycleTimesGenerator::GenerateCellCycleTimeSequence()
{
    if (mVectorCreated)
    {
        EXCEPTION("Trying to generate the cell cycle times twice. Need to call CellCycleTimesGenerator::Destroy() first.");
    }
    else
    {
        unsigned number_stored_times = 15000u;
        mCellCycleTimes.reserve(number_stored_times);

        RandomNumberGenerator* p_random_number_generator = RandomNumberGenerator::Instance();
        p_random_number_generator->Reseed(mRandomSeed);

        for (unsigned index = 0; index < 15000u; index++)
        {
            mCellCycleTimes.push_back( p_random_number_generator->ExponentialRandomDeviate(mRate) );
        }

        mCurrentIndex = 0;
        mVectorCreated = true;
    }
}

void CellCycleTimesGenerator::SetRate(double rate)
{
    if( mVectorCreated)
    {
        EXCEPTION("You cannot reset the rate after cell cycle times are created.");
    }
    else
    {
        mRate = rate;
    }
}

double CellCycleTimesGenerator::GetRate()
{
    return mRate;
}

double CellCycleTimesGenerator::GetNextCellCycleTime()
{
    if(!mVectorCreated)
    {
        EXCEPTION("When using FixedSequenceCellCycleModel one must call CellCycleTimesGenerator::Instance()->GenerateCellCycleTimeSequence()"
                " before the start of the simulation.");
    }
    else
    {
        double new_cell_cycle_time = mCellCycleTimes[mCurrentIndex];
        mCurrentIndex += 1u;
        return new_cell_cycle_time;
    }
}