00001 /* 00002 00003 Copyright (C) University of Oxford, 2005-2011 00004 00005 University of Oxford means the Chancellor, Masters and Scholars of the 00006 University of Oxford, having an administrative office at Wellington 00007 Square, Oxford OX1 2JD, UK. 00008 00009 This file is part of Chaste. 00010 00011 Chaste is free software: you can redistribute it and/or modify it 00012 under the terms of the GNU Lesser General Public License as published 00013 by the Free Software Foundation, either version 2.1 of the License, or 00014 (at your option) any later version. 00015 00016 Chaste is distributed in the hope that it will be useful, but WITHOUT 00017 ANY WARRANTY; without even the implied warranty of MERCHANTABILITY or 00018 FITNESS FOR A PARTICULAR PURPOSE. See the GNU Lesser General Public 00019 License for more details. The offer of Chaste under the terms of the 00020 License is subject to the License being interpreted in accordance with 00021 English Law and subject to any action against the University of Oxford 00022 being under the jurisdiction of the English Courts. 00023 00024 You should have received a copy of the GNU Lesser General Public License 00025 along with Chaste. If not, see <http://www.gnu.org/licenses/>. 00026 00027 */ 00028 00029 #include "VolumeDependentAveragedSourcePde.hpp" 00030 #include "ApoptoticCellProperty.hpp" 00031 00032 template<unsigned DIM> 00033 VolumeDependentAveragedSourcePde<DIM>::VolumeDependentAveragedSourcePde(AbstractCellPopulation<DIM>& rCellPopulation, double coefficient) 00034 : AveragedSourcePde<DIM>(rCellPopulation, coefficient) 00035 { 00036 assert(dynamic_cast<NodeBasedCellPopulation<DIM>*>(&(this->mrCellPopulation))); 00037 mpStaticCastCellPopulation = static_cast<NodeBasedCellPopulation<DIM>*>(&(this->mrCellPopulation)); 00038 } 00039 00040 template<unsigned DIM> 00041 void VolumeDependentAveragedSourcePde<DIM>::SetupSourceTerms(TetrahedralMesh<DIM,DIM>& rCoarseMesh, std::map< CellPtr, unsigned >* pCellPdeElementMap) // must be called before solve 00042 { 00043 // Allocate memory 00044 this->mCellDensityOnCoarseElements.resize(rCoarseMesh.GetNumElements()); 00045 for (unsigned elem_index=0; elem_index<this->mCellDensityOnCoarseElements.size(); elem_index++) 00046 { 00047 this->mCellDensityOnCoarseElements[elem_index] = 0.0; 00048 } 00049 00050 // Loop over cells, find which coarse element it is in, and add volume to the mSourceTermOnCoarseElements[elem_index]; 00051 for (typename AbstractCellPopulation<DIM>::Iterator cell_iter = this->mrCellPopulation.Begin(); 00052 cell_iter != this->mrCellPopulation.End(); 00053 ++cell_iter) 00054 { 00055 unsigned elem_index = 0; 00056 const ChastePoint<DIM>& r_position_of_cell = this->mrCellPopulation.GetLocationOfCellCentre(*cell_iter); 00057 00058 if (pCellPdeElementMap != NULL) 00059 { 00060 elem_index = (*pCellPdeElementMap)[*cell_iter]; 00061 } 00062 else 00063 { 00064 elem_index = rCoarseMesh.GetContainingElementIndex(r_position_of_cell); 00065 } 00066 00067 unsigned node_index = this->mrCellPopulation.GetLocationIndexUsingCell(*cell_iter); 00068 00069 // Uptake normalised to 1 for unit cell 00070 double radius = mpStaticCastCellPopulation->rGetMesh().GetCellRadius(node_index); 00071 double cell_weight = radius*radius; 00072 00073 bool cell_is_apoptotic = cell_iter->template HasCellProperty<ApoptoticCellProperty>(); 00074 if (!cell_is_apoptotic) 00075 { 00076 this->mCellDensityOnCoarseElements[elem_index] += cell_weight; 00077 } 00078 } 00079 00080 // Then divide each entry of mSourceTermOnCoarseElements by the element's area 00081 c_matrix<double, DIM, DIM> jacobian; 00082 double det; 00083 for (unsigned elem_index=0; elem_index<this->mCellDensityOnCoarseElements.size(); elem_index++) 00084 { 00085 rCoarseMesh.GetElement(elem_index)->CalculateJacobian(jacobian, det); 00086 this->mCellDensityOnCoarseElements[elem_index] /= rCoarseMesh.GetElement(elem_index)->GetVolume(det); 00087 } 00088 } 00089 00091 // Explicit instantiation 00093 00094 template class VolumeDependentAveragedSourcePde<1>; 00095 template class VolumeDependentAveragedSourcePde<2>; 00096 template class VolumeDependentAveragedSourcePde<3>; 00097 00098 // Serialization for Boost >= 1.36 00099 #include "SerializationExportWrapperForCpp.hpp" 00100 EXPORT_TEMPLATE_CLASS_SAME_DIMS(VolumeDependentAveragedSourcePde)