StochasticOxygenBasedCellCycleModel Class Reference

#include <StochasticOxygenBasedCellCycleModel.hpp>

Inherits SimpleOxygenBasedCellCycleModel.

Collaboration diagram for StochasticOxygenBasedCellCycleModel:

[legend]

List of all members.

Public Member Functions
	StochasticOxygenBasedCellCycleModel ()
void	InitialiseDaughterCell ()
void	Initialise ()
void	ResetForDivision ()
double	GetG2Duration ()
AbstractCellCycleModel *	CreateCellCycleModel ()
virtual void	OutputCellCycleModelParameters (out_stream &rParamsFile)
Private Member Functions
template<class Archive >
void	serialize (Archive &archive, const unsigned int version)
void	GenerateStochasticG2Duration ()
Private Attributes
double	mStochasticG2Duration
Friends
class	TestSimpleCellCycleModels
class	boost::serialization::access

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Detailed Description

Stochastic oxygen-based cell-cycle model.

A simple oxygen-dependent cell-cycle model that inherits from SimpleOxygenBasedCellCycleModel and in addition spends a random duration in G2 phase.

Definition at line 42 of file StochasticOxygenBasedCellCycleModel.hpp.

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Constructor & Destructor Documentation

StochasticOxygenBasedCellCycleModel::StochasticOxygenBasedCellCycleModel

(

)

Constructor.

Definition at line 33 of file StochasticOxygenBasedCellCycleModel.cpp.

Referenced by CreateCellCycleModel().

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Member Function Documentation

AbstractCellCycleModel * StochasticOxygenBasedCellCycleModel::CreateCellCycleModel

(

)

[virtual]

Overridden builder method to create new copies of this cell-cycle model.

Reimplemented from SimpleOxygenBasedCellCycleModel.

Definition at line 77 of file StochasticOxygenBasedCellCycleModel.cpp.

References AbstractCellCycleModel::mBirthTime, AbstractCellCycleModel::mCellProliferativeType, SimpleOxygenBasedCellCycleModel::mCriticalHypoxicDuration, SimpleOxygenBasedCellCycleModel::mCurrentHypoxiaOnsetTime, AbstractCellCycleModel::mDimension, AbstractCellCycleModel::mG2Duration, SimpleOxygenBasedCellCycleModel::mHypoxicConcentration, AbstractCellCycleModel::mMDuration, AbstractCellCycleModel::mMinimumGapDuration, SimpleOxygenBasedCellCycleModel::mQuiescentConcentration, AbstractCellCycleModel::mSDuration, AbstractCellCycleModel::mStemCellG1Duration, AbstractCellCycleModel::mTransitCellG1Duration, AbstractCellCycleModel::SetBirthTime(), AbstractCellCycleModel::SetCellProliferativeType(), SimpleOxygenBasedCellCycleModel::SetCriticalHypoxicDuration(), SimpleOxygenBasedCellCycleModel::SetCurrentHypoxiaOnsetTime(), AbstractCellCycleModel::SetDimension(), AbstractCellCycleModel::SetG2Duration(), SimpleOxygenBasedCellCycleModel::SetHypoxicConcentration(), AbstractCellCycleModel::SetMDuration(), AbstractCellCycleModel::SetMinimumGapDuration(), SimpleOxygenBasedCellCycleModel::SetQuiescentConcentration(), AbstractCellCycleModel::SetSDuration(), AbstractCellCycleModel::SetStemCellG1Duration(), AbstractCellCycleModel::SetTransitCellG1Duration(), and StochasticOxygenBasedCellCycleModel().

void StochasticOxygenBasedCellCycleModel::GenerateStochasticG2Duration

(

)

[private]

Stochastically set the G2 duration. Called on cell creation at the start of a simulation, and for both parent and daughter cells at cell division.

Definition at line 38 of file StochasticOxygenBasedCellCycleModel.cpp.

References GetG2Duration(), RandomNumberGenerator::Instance(), AbstractCellCycleModel::mMinimumGapDuration, mStochasticG2Duration, and RandomNumberGenerator::NormalRandomDeviate().

Referenced by Initialise(), InitialiseDaughterCell(), and ResetForDivision().

double StochasticOxygenBasedCellCycleModel::GetG2Duration

(

)

[virtual]

Returns:

mStochasticG2Duration.

Reimplemented from AbstractCellCycleModel.

Definition at line 72 of file StochasticOxygenBasedCellCycleModel.cpp.

References mStochasticG2Duration.

Referenced by GenerateStochasticG2Duration().

void StochasticOxygenBasedCellCycleModel::Initialise

(

void

)

[virtual]

Initialise the cell-cycle model at the start of a simulation.

Reimplemented from AbstractSimpleCellCycleModel.

Definition at line 60 of file StochasticOxygenBasedCellCycleModel.cpp.

References GenerateStochasticG2Duration().

void StochasticOxygenBasedCellCycleModel::InitialiseDaughterCell

(

)

[virtual]

Overridden InitialiseDaughterCell() method.

Reimplemented from AbstractSimpleCellCycleModel.

Definition at line 54 of file StochasticOxygenBasedCellCycleModel.cpp.

References GenerateStochasticG2Duration().

void StochasticOxygenBasedCellCycleModel::OutputCellCycleModelParameters

(

out_stream &

rParamsFile

)

[virtual]

Outputs cell cycle model parameters to file.

Parameters:

rParamsFile

the file stream to which the parameters are output

Reimplemented from SimpleOxygenBasedCellCycleModel.

Definition at line 112 of file StochasticOxygenBasedCellCycleModel.cpp.

void StochasticOxygenBasedCellCycleModel::ResetForDivision

(

)

[virtual]

Overridden ResetForDivision() method.

Reimplemented from AbstractSimpleCellCycleModel.

Definition at line 66 of file StochasticOxygenBasedCellCycleModel.cpp.

References GenerateStochasticG2Duration().

template<class Archive >

void StochasticOxygenBasedCellCycleModel::serialize	(	Archive &	archive,
		const unsigned int	version
	)			[inline, private]

Archive the cell-cycle model.

Parameters:

	archive	the archive
	version	the current version of this class

Reimplemented from SimpleOxygenBasedCellCycleModel.

Definition at line 50 of file StochasticOxygenBasedCellCycleModel.hpp.

References SerializableSingleton< SINGLETON_CLASS >::GetSerializationWrapper(), RandomNumberGenerator::Instance(), and mStochasticG2Duration.

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Friends And Related Function Documentation

friend class boost::serialization::access [friend]

Needed for serialization.

Reimplemented from SimpleOxygenBasedCellCycleModel.

Definition at line 48 of file StochasticOxygenBasedCellCycleModel.hpp.

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Member Data Documentation

double StochasticOxygenBasedCellCycleModel::mStochasticG2Duration [private]

The duration of the G2 phase, set stochastically.

Definition at line 64 of file StochasticOxygenBasedCellCycleModel.hpp.

Referenced by GenerateStochasticG2Duration(), GetG2Duration(), and serialize().

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The documentation for this class was generated from the following files:

• cell_based/src/population/cell/cycle/StochasticOxygenBasedCellCycleModel.hpp
• cell_based/src/population/cell/cycle/StochasticOxygenBasedCellCycleModel.cpp