2023 Oxford Workshop

A workshop on cell-based Chaste: an introduction to basic functionality, and a showcase of the latest additions to the codebase.

Event details

Resources

Links to slides and practical materials are available at https://github.com/Chaste/chaste-workshop-materials-2023

Where

Doctoral Training Centre 1-4 Keble Road Oxford OX1 3NP UK

Map

When

Monday 11 September to Thursday 14 September 2023

Details

We are pleased to announce a workshop on cell-based modelling within Chaste (Cancer, Heart and Soft-Tissue Environment), an open-source multi-scale framework for the computational modelling of biological systems. This software library consists of object-oriented C++ code, developed using an agile approach. All software is tested, robust, reliable and extensible. The library enables general simulations to be undertaken and includes tools to visualise, analyse and automatically curate and store simulation results, thus expediting model development.

The workshop will introduce Chaste’s basic functionality, and showcase the latest additions to the codebase, including more varied cell-based modelling approaches and a Python interface. Through a combination of lectures, case studies, and hands-on practicals, participants will learn how to implement and run simulations of several model biological systems. Time is also reserved for participants to receive help and tuition in how to apply Chaste to novel biological problems, including their own research.

This workshop is aimed at anyone with an interest in developing, or learning more about multi-scale computational cell based models. In order to get the most out of the workshop participants should have a working knowledge of C++ and some experience of mathematical modelling in the life sciences. On completion of the workshop, participants will be able to use Chaste to develop a basic simulation of a biological problem related to their research.

For additional information, please contact Fergus Cooper .

We have funding to cover accommodation and travel within the UK for PhD students and early career researchers attending this workshop.

We look forward to your participation!

Timetable

Monday 11 September (materials)

TimeDescription
10:00-11:00Arrivals
11:00-11:15Introduction and welcome
11:15-12:30Lightning introductions from attendees
12:00-12:45Introduction to vertex models, and other cell-based paradigms
12:30-13:30 13:00-14:00Lunch
14:00-14:30Accommodation check in (for those staying at Wycliffe Hall, OX2 6PW)
14:30-17:00Practical session, using the PyChaste python frontend for Chaste
17:00-17:30Getting familiar with Chaste terminology and code structure

Tuesday 12 September (materials)

TimeDescription
09:30-10:00Scientific case study #1: Adrianna Zanca
10:00-11:00Get up and running with Chaste in VS Code using Docker and C++
11:00-12:30Practical session, on how to use the C++ interface to make more substantial changes to models
12:30-13:30Lunch
13:30-14:00Scientific case study #2: Josh Bull
14:00-16:30New functionality for implementing more detailed cell shape representations
16:30-17:00Overview of the new Chaste infrastructure, and how to access help and support
17:00-17:30Aside: an introduction to Research Software Engineering
18:30-20:30Dinner at Brasserie Blanc

Wednesday 13 September (materials)

TimeDescription
09:30-10:00Scientific case study #3: Gary Mirams
10:00-12:30Coupling cells/tissues to the microenvironment
12:30-13:30Lunch
13:30-14:00Scientific case study #4: Josh Moore
14:00-16:00Modeling cell-environment feedback
16:00-17:00Lightning wrapups

Thursday 14 September (optional hackathon)

  • Bring your own project, or
  • Get help from the Chaste development team to get started with a model

Registration

We have funding to cover accommodation and travel within the UK for students and early career researchers attending this workshop.