SingleOdeWntCellCycleModel.hpp

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*/
 
#ifndef SINGLEODEWNTCELLCYCLEMODEL_HPP_
#define SINGLEODEWNTCELLCYCLEMODEL_HPP_
 
#include "ChasteSerialization.hpp"
#include <boost/serialization/base_object.hpp>
 
#include <cfloat>
 
#include "SimpleWntCellCycleModel.hpp"
#include "Mirams2010WntOdeSystem.hpp"
#include "AbstractCellCycleModelOdeSolver.hpp"
#include "CellCycleModelOdeHandler.hpp"
 
class SingleOdeWntCellCycleModel : public SimpleWntCellCycleModel, public CellCycleModelOdeHandler
{
private:
 
    friend class boost::serialization::access;
    template<class Archive>
    void serialize(Archive & archive, const unsigned int version)
    {
        archive & boost::serialization::base_object<SimpleWntCellCycleModel>(*this);
        archive & boost::serialization::base_object<CellCycleModelOdeHandler>(*this);
        archive & mBetaCateninDivisionThreshold;
    }
 
    double mBetaCateninDivisionThreshold;
 
    void ChangeCellProliferativeTypeDueToCurrentBetaCateninLevel();
 
    virtual void AdjustOdeParameters(double currentTime);
 
protected:
 
    SingleOdeWntCellCycleModel(const SingleOdeWntCellCycleModel& rModel);
 
public:
 
    SingleOdeWntCellCycleModel(boost::shared_ptr<AbstractCellCycleModelOdeSolver> pOdeSolver = boost::shared_ptr<AbstractCellCycleModelOdeSolver>());
 
    void Initialise();
 
    void UpdateCellCyclePhase();
 
    AbstractCellCycleModel* CreateCellCycleModel();
 
    double GetBetaCateninConcentration();
 
    void SetBetaCateninDivisionThreshold(double betaCateninDivisionThreshold);
 
    double GetBetaCateninDivisionThreshold();
 
    virtual void OutputCellCycleModelParameters(out_stream& rParamsFile);
};
 
// Declare identifier for the serializer
#include "SerializationExportWrapper.hpp"
CHASTE_CLASS_EXPORT(SingleOdeWntCellCycleModel)
#include "CellCycleModelOdeSolverExportWrapper.hpp"
EXPORT_CELL_CYCLE_MODEL_ODE_SOLVER(SingleOdeWntCellCycleModel)
 
#endif /*SINGLEODEWNTCELLCYCLEMODEL_HPP_*/